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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                                 
                                                  1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                                  E   V   K   L   V   E   S   G   G       G   L   V   Q   P   G   R   S   L   R 
  RatNor_1_chr6 IGHV4-1*01 ORF V-REGION gDNA     gag gtg aag ctt gtc gag tct gga ggt ... ggc ttg gtg cag cct gga aga tcc ttg aga
                                                                                                                                
  AABR03049003  IGHV4-1*01 ORF V-REGION gDNA     --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---


                                                                         _____________________CDR1-IMGT______________________    
                                                 
                                                  21  22  23  24  25  26  27  28  29  30  31  32 32.1 33  34  35  36  37  38  39 
                                                  L   S   C   A   T   S   G   F   S   F                       S   S   Y   W   M 
  RatNor_1_chr6 IGHV4-1*01 ORF V-REGION gDNA     ctc tct tgt gca acc tct gga ttc agt ttt ... ... ... ... ... agt agc tac tgg atg
                                                                                                                                
  AABR03049003  IGHV4-1*01 ORF V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- ---


                                                                                                                 _______________C
                                                 
                                                  40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                  S   W   F   R   Q   A   P   E   K   R   L   E   W   I   G   E   I   S   H   T 
  RatNor_1_chr6 IGHV4-1*01 ORF V-REGION gDNA     agc tgg ttc cgg cag gct cca gag aag agg cta gaa tgg atc gga gaa att agt cat acc
                                                                                                                                
  AABR03049003  IGHV4-1*01 ORF V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                 DR2-IMGT________________                                                        
                                                 
                                                  60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                          S   N   T   I   N   Y   T   P   S   L   K       D   K   F   T   I   S 
  RatNor_1_chr6 IGHV4-1*01 ORF V-REGION gDNA     ... ... agc aat aca ata aac tac aca cca tct ttg aag ... gat aaa ttc acc atc tcc
                                                                                                                                
  AABR03049003  IGHV4-1*01 ORF V-REGION gDNA     ... ... --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- ---


                                                                                                                                 
                                                 
                                                  80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                                  R   D   N   P   Q   N   T   L   Y   L   Q   M   S   N   L   R   P   E   D   T 
  RatNor_1_chr6 IGHV4-1*01 ORF V-REGION gDNA     aga gac aat ccc caa aac act ctg tat ctg caa atg agc aac ctg aga cct gag gac aca
                                                                                                                                
  AABR03049003  IGHV4-1*01 ORF V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                         _CDR3-IMGT__
                                                 
                                                 100 101 102 102A103 104 105 106 
                                                  A   I   Y       S   C   T   R  
  RatNor_1_chr6 IGHV4-1*01 ORF V-REGION gDNA     gcc att tat ... tcc tgt aca aga ga
                                                                                 
  AABR03049003  IGHV4-1*01 ORF V-REGION gDNA     --- --- --- ... --- --- --- --- --

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
09/02/2016
Last updated:
02/08/2016
Authors:
Mélanie Arrivet