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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                               
                                                1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                                E   V   K   L   V   E   S   G   G       G   L   V   Q   P   G   R   S   L   K 
  RatNor_2_chr6 IGHV4-2*01 F V-REGION gDNA     gag gtg aaa ctt gtc gag tct gga ggt ... ggc ctg gtg caa cct gga aga tcc ttg aaa
                                                                                                                              
  AABR03048851  IGHV4-2*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---


                                                                       _____________________CDR1-IMGT______________________    
                                               
                                                21  22  23  24  25  26  27  28  29  30  31  32 32.1 33  34  35  36  37  38  39 
                                                L   S   C   A   A   S   G   F   N   F                       N   D   Y   W   M 
  RatNor_2_chr6 IGHV4-2*01 F V-REGION gDNA     ctc tcc tgt gca gcc tct gga ttc aat ttt ... ... ... ... ... aat gat tac tgg atg
                                                                                                                              
  AABR03048851  IGHV4-2*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- ---


                                                                                                               _______________C
                                               
                                                40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                G   W   V   R   Q   A   P   G   K   G   L   E   W   I   G   E   I   N   K   D 
  RatNor_2_chr6 IGHV4-2*01 F V-REGION gDNA     ggc tgg gtc cgg cag gct cca ggg aag ggg cta gaa tgg att gga gaa att aat aag gat
                                                                                                                              
  AABR03048851  IGHV4-2*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                               DR2-IMGT________________                                                        
                                               
                                                60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                        S   S   T   I   N   Y   T   P   S   L   K       D   K   F   T   I   S 
  RatNor_2_chr6 IGHV4-2*01 F V-REGION gDNA     ... ... agc agt aca ata aac tat act cca tcc ttg aag ... gat aaa ttc acc atc tcc
                                                                                                                              
  AABR03048851  IGHV4-2*01 F V-REGION gDNA     ... ... --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- ---


                                                                                                                               
                                               
                                                80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                                R   D   N   A   Q   N   T   L   Y   L   Q   M   S   K   L   G   S   E   D   T 
  RatNor_2_chr6 IGHV4-2*01 F V-REGION gDNA     aga gac aat gcc caa aac act ctg tac ctg caa atg agc aaa ctg gga tct gag gac aca
                                                                                                                              
  AABR03048851  IGHV4-2*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                       _CDR3-IMGT__
                                               
                                               100 101 102 102A103 104 105 106 
                                                A   I   Y       Y   C   A   R  
  RatNor_2_chr6 IGHV4-2*01 F V-REGION gDNA     gcc att tat ... tac tgt gca aga gc
                                                                               
  AABR03048851  IGHV4-2*01 F V-REGION gDNA     --- --- --- ... --- --- --- --- --

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
09/02/2016
Last updated:
02/08/2016
Authors:
Mélanie Arrivet