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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                               
                                                1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                                G   V   K   L   V   E   T   G   G       G   L   V   *   S   G   K   S   L   R 
  RatNor_2_chr6 IGHV4-4*01 P V-REGION gDNA     ggg gtg aag ctt gtt gag act gga ggt ... ggc ctg gta tag tct gga aaa tcc ttg agg
                                                                                                                              
  AABR03050276  IGHV4-4*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---


                                                                       _____________________CDR1-IMGT______________________    
                                               
                                                21  22  23  24  25  26  27  28  29  30  31  32 32.1 33  34  35  36  37  38  39 
                                                L   S   C   A   T   S   I   F   S   F                       N   S   *   W   M 
  RatNor_2_chr6 IGHV4-4*01 P V-REGION gDNA     ctc tcc tgt gca acc tcc ata ttc agt ttt ... ... ... ... ... aat agc taa tgg atg
                                                                                                                              
  AABR03050276  IGHV4-4*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- ---


                                                                                                               _______________C
                                               
                                                40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                S   W   N   R   E   T   P   G   K   G   P   E   *   I   G   E   I   N   P   A 
  RatNor_2_chr6 IGHV4-4*01 P V-REGION gDNA     agc tgg aac cgg gag act cca ggg aag ggg cca gaa tga att gga gaa att aat cca gct
                                                                                                                              
  AABR03050276  IGHV4-4*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                               DR2-IMGT________________                                                        
                                               
                                                60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                        D   S   T   V   N   Y   T   P   S   L   G       D   K   F   T   I   S 
  RatNor_2_chr6 IGHV4-4*01 P V-REGION gDNA     ... ... gac agt aca gta aac tac aca cca tct tta ggg ... gat aaa ttc acc ata tcc
                                                                                                                              
  AABR03050276  IGHV4-4*01 P V-REGION gDNA     ... ... --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- ---


                                                                                                                               
                                               
                                                80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                                R   D   N   T   Q   N   T   L   Y   L   Q   M   N   K   M   *   S   E   D   T 
  RatNor_2_chr6 IGHV4-4*01 P V-REGION gDNA     aga gac aat acc caa aac act ctc tac ctg caa atg aat aaa atg tga tct gag gac aca
                                                                                                                              
  AABR03050276  IGHV4-4*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                       _CDR3-IMGT__
                                               
                                               100 101 102 102A103 104 105 106 
                                                A   S   N       Y   C   T   M  
  RatNor_2_chr6 IGHV4-4*01 P V-REGION gDNA     gcc agt aat ... tac tgc aca atg ga
                                                                               
  AABR03050276  IGHV4-4*01 P V-REGION gDNA     --- --- --- ... --- --- --- --- --

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
09/02/2016
Last updated:
02/08/2016
Authors:
Mélanie Arrivet