When several alleles are shown, the nucleotide mutations and amino acid
changes for a given codon are indicated in red letters. These polymorphic mutations are reported in
Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the
IMGT unique numbering.
Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 E V Q L V E S G G G L V Q P G R S L K RatNor_1_chr6 IGHV5-23*01 P V-REGION gDNA gag gtg cag ctg gtg gag tct ggg gga ... ggc tta gtg cag cct gga agg tcc ctg aaa AABR03048499 IGHV5-23*01 P V-REGION gDNA --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- _____________________CDR1-IMGT______________________ 21 22 23 24 25 26 27 28 29 30 31 32 32.1 33 34 35 36 37 38 39 L S C A A S G F T F S N Y Y M RatNor_1_chr6 IGHV5-23*01 P V-REGION gDNA ctc tcc tgt gca gcc tca gga ttc act ttc ... ... ... ... ... agt aac tat tac atg AABR03048499 IGHV5-23*01 P V-REGION gDNA --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- _______________C 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 A W V C Q A P K K G L E W V A T I S P S RatNor_1_chr6 IGHV5-23*01 P V-REGION gDNA gcc tgg gtc tgc cag gct cca aag aag ggt ctg gag tgg gtc gca aca att agt cct agt AABR03048499 IGHV5-23*01 P V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DR2-IMGT________________ 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 G G S N Y Y R D S M K G R F T I S RatNor_1_chr6 IGHV5-23*01 P V-REGION gDNA ... ... ggt ggt agc aat tac tat cga gac tcc atg aag ... ggc cga ttc act atc tcc AABR03048499 IGHV5-23*01 P V-REGION gDNA ... ... --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 K D N A K S T L Y L Q M D T W R S E D T RatNor_1_chr6 IGHV5-23*01 P V-REGION gDNA aaa gat aat gca aaa agc acc cta tac ctg caa atg gac act tgg agg tct gag gac acg AABR03048499 IGHV5-23*01 P V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- _CDR3-IMGT__ 100 101 102 102A103 104 105 106 A T Y Y C T T RatNor_1_chr6 IGHV5-23*01 P V-REGION gDNA gcc act tat ... tac tgt aca aca ga AABR03048499 IGHV5-23*01 P V-REGION gDNA --- --- --- ... --- --- --- --- --
This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).
Software material and data coming from IMGT server may be used for academic research only,
provided that it is referred to IMGT®, and cited as
"IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org
(founder and director: Marie-Paule Lefranc, Montpellier, France)."
References to cite:
Lefranc, M.-P. et al.,
Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209
Full text
Cover;
Ruiz, M. et al.,
Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219
Full text;
Lefranc, M.-P.,
Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207
Full text;
Lefranc, M.-P.,
Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085
Full text;
Lefranc, M.-P. et al.,
In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005);
Lefranc, M.-P. et al.,
Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056
Full text.
For any other use please contact Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr.
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