Here you are: IMGT Web resources > IMGT Repertoire > Proteins and alleles

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                    
                                    
                                    1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                     A   S   I   Q   G   P   L   V   Y   P   L   T   S   C   C   K 
  AB699687 IGHE*01   F   CH1 gDNA                   gcc tcc atc cag ggc cca ctg gtc tac ccc ttg act tct tgt tgc aaa
                                                                                                                   
  U96100   IGHE*01   F   CH1 cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH1 gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                _____AB_____                                            ____________
                                                15.1    15.3                                                        
                                     13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                     T   G                   A   T   S   K   T   L   G   C   L   V   R   G   Y   F 
  AB699687 IGHE*01   F   CH1 gDNA   acc ggc ... ... ... ... gcc acc tcc aag acg ctg ggc tgc ctg gtc agg ggc tac ttc
                                                                                                                   
  U96100   IGHE*01   F   CH1 cDNA   --- --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH1 gDNA   --- --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                    _______BC___________________                            _____________CD_________
                                                                                            45.1    45.3    45.5    
                                     30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                     P           E   P   V   T   V   T   W   D   T   G   S   L   N   S             
  AB699687 IGHE*01   F   CH1 gDNA   cca ... ... gag cca gtg acc gtg acc tgg gac aca gga tcc ctg aat agt ... ... ...
                                                                                                                   
  U96100   IGHE*01   F   CH1 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                                                                                                                   
  AB699688 IGHE*01   F   CH1 gDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                    ____                                ___________________________DE_______________
                                    45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                         77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         S   T   L   T   F   P   A   V   Q   D   S   S   S                       S 
  AB699687 IGHE*01   F   CH1 gDNA   ... agc acc ctg acc ttc cct gct gtc caa gac tcg agc tcc ... ... ... ... ... agc
                                                                                                                   
  U96100   IGHE*01   F   CH1 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---
                                                                                                                   
  AB699688 IGHE*01   F   CH1 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---


                                    ____________                                                ___EF___            
                                        85.2                                                    96.1                
                                    85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                     L   Y   T   V   T   S   Q   V   T   I   L   G   E   W                   T   N 
  AB699687 IGHE*01   F   CH1 gDNA   ctc tac acg gtc acc agc cag gtg acc atc ttg ggc gag tgg ... ... ... ... acc aac
                                                                                                                   
  U96100   IGHE*01   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---


                                                        _________________________FG_________________________        
                                    
                                    100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                     Q   K   L   T   C   S   V   A   H   A                   A   N   T   T   I   R 
  AB699687 IGHE*01   F   CH1 gDNA   cag aag ctc acc tgc agt gtg gct cac gct ... ... ... ... gca aac acc acc atc cgg
                                                                                                                   
  U96100   IGHE*01   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---


                                                
                                    
                                    120 121 122 
                                     T   I   T  
  AB699687 IGHE*01   F   CH1 gDNA   acc atc aca 
                                                    
  U96100   IGHE*01   F   CH1 cDNA   --- --- ---     
                                                
  AB699688 IGHE*01   F   CH1 gDNA   --- --- ---  




                                                                                                                    
                                    
                                    1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                         G   C   T   K   N   F   T   D   P   S   L   R   F   F   Y   S   S   C   D 
  AB699687 IGHE*01   F   CH2 gDNA       ggg tgc acc aag aat ttc acc gac ccc tcc ttg agg ttc ttc tac tcc tcc tgc gac
                                                                                                                   
  U96100   IGHE*01   F   CH2 cDNA       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH2 gDNA       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                _____AB_____                                            ____________
                                                15.1    15.3                                                        
                                     13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                     P   H   G   D   A       Q   A   T   I   H   L   R   C   Y   I   S   G   Y   T 
  AB699687 IGHE*01   F   CH2 gDNA   ccc cac ggt gac gcc ... caa gcc acc atc cat ctc cga tgc tat atc tcc ggc tac acc
                                                                                                                   
  U96100   IGHE*01   F   CH2 cDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH2 gDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                    _______BC___________________                            _____________CD_________
                                                                                            45.1    45.3    45.5    
                                     30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                     P           G   K   M   K   V   T   W   L   V   D   G   Q   E   D   R   N     
  AB699687 IGHE*01   F   CH2 gDNA   ccc ... ... ggc aaa atg aag gtc acc tgg ctg gtg gac ggg cag gag gat aga aac ...
                                                                                                                   
  U96100   IGHE*01   F   CH2 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                   
  AB699688 IGHE*01   F   CH2 gDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...


                                    ____                                ___________________________DE_______________
                                    45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                         77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         L   F   S   Y   T   A   P   D   Q   L   E   G                           K 
  AB699687 IGHE*01   F   CH2 gDNA   ... ctg ttc tcg tac acc gcc ccc gac cag ctg gag ggc ... ... ... ... ... ... aag
                                                                                                                   
  U96100   IGHE*01   F   CH2 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                                                                                   
  AB699688 IGHE*01   F   CH2 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                    ____________                                                ___EF___            
                                        85.2                                                    96.1                
                                    85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                     L   A   S   T   Y   S   E   V   N   I   T   Q   G   Q   W           A   S   Q 
  AB699687 IGHE*01   F   CH2 gDNA   ctg gcc tcc acc tac agc gag gtc aac atc acg cag ggc cag tgg ... ... gcg tct cag
                                                                                                                   
  U96100   IGHE*01   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                        _________________________FG_________________________        
                                    
                                    100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                     I   T   Y   T   C   Q   V   S   Y   Y                   G   F   I   Y   E   K 
  AB699687 IGHE*01   F   CH2 gDNA   atc acg tac acc tgc cag gtc tcc tat tac ... ... ... ... ggc ttc atc tat gaa aaa
                                                                                                                   
  U96100   IGHE*01   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---


                                                            
                                    
                                    120 121 122 123 124 125 
                                     H   A   L   R   C   T  
  AB699687 IGHE*01   F   CH2 gDNA   cac gcc ctc agg tgc aca 
                                                            
  U96100   IGHE*01   F   CH2 cDNA   --- --- --- --- --- --- 
                                                            
  AB699688 IGHE*01   F   CH2 gDNA   --- --- --- --- --- ---  




                                                                                                                    
                                    
                                    1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                             A   E   S   E   P   R   G   V   S   A   Y   L   S   P   P   T   P   L 
  AB699687 IGHE*01   F   CH3 gDNA           gcg gag tcc gag ccc cgt ggg gtg agc gct tac ctg agt ccg ccc acg ccc ctc
                                                                                                                   
  U96100   IGHE*01   F   CH3 cDNA           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH3 gDNA           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                _____AB_____                                            ____________
                                                15.1    15.3                                                        
                                     13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                     D   L   Y   V           H   K   S   P   K   L   T   C   L   V   V   D   L   A 
  AB699687 IGHE*01   F   CH3 gDNA   gac ctg tac gtc ... ... cac aag tcg ccc aag ctc acc tgc ctg gtg gtg gac ctg gcc
                                                                                                                   
  U96100   IGHE*01   F   CH3 cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH3 gDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                    _______BC___________________                            _____________CD_________
                                                                                            45.1    45.3    45.5    
                                     30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                     S   S       E   N   V   N   L   L   W   S   R   E   N   K   G   G   V   I   L 
  AB699687 IGHE*01   F   CH3 gDNA   agc tcg ... gag aac gtg aac ctg ttg tgg tcc agg gag aac aag ggg ggc gtg att ctc
                                                                                                                   
  U96100   IGHE*01   F   CH3 cDNA   --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH3 gDNA   --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                    ____                                ___________________________DE_______________
                                    45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                         77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                     P   P   P   G   P   P   V   I   K   P   Q   F   N                           G 
  AB699687 IGHE*01   F   CH3 gDNA   ccg cct ccg ggc ccg ccc gtc atc aag ccc cag ttc aac ... ... ... ... ... ... ggc
                                                                                                                   
  U96100   IGHE*01   F   CH3 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                                                                                   
  AB699688 IGHE*01   F   CH3 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                    ____________                                                ___EF___            
                                        85.2                                                    96.1                
                                    85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                     T   F   S   A   T   S   T   L   P   V   N   V   S   D   W           I   E   G 
  AB699687 IGHE*01   F   CH3 gDNA   acg ttc agc gcc acg tcc aca ctg ccg gtg aat gtc agc gac tgg ... ... att gag ggc
                                                                                                                   
  U96100   IGHE*01   F   CH3 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH3 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                        _________________________FG_________________________        
                                    
                                    100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                     E   T   Y   Y   C   N   V   T   H   P   D           L   P   K   P   I   L   R 
  AB699687 IGHE*01   F   CH3 gDNA   gag acc tac tat tgc aac gtg acc cac ccg gac ... ... ttg ccc aag ccc atc ctg cgc
                                                                                                                   
  U96100   IGHE*01   F   CH3 cDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                                                                                                   
  AB699688 IGHE*01   F   CH3 gDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                                            
                                    
                                    120 121 122 123 124 125 
                                     S   I   S   K   G   P  
  AB699687 IGHE*01   F   CH3 gDNA   tcc atc tcc aag ggc cct 
                                                            
  U96100   IGHE*01   F   CH3 cDNA   --- --- --- --- --- --- 
                                                            
  AB699688 IGHE*01   F   CH3 gDNA   --- --- --- --- --- ---  




                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                         G   K   R   V   T   P   E   V   Y   V   L   W   S   P   D   E 
  AB699687 IGHE*01   F   CH4-CHS gDNA                   ggc aag cgc gtg acc ccc gag gtc tat gtg ctc tgg agc cct gac gag
                                                                                                                       
  U96100   IGHE*01   F   CH4-CHS cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                       
  AB699688 IGHE*01   F   CH4-CHS gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         L   K                   K   G   R   L   T   L   T   C   L   I   Q   N   F   F 
  AB699687 IGHE*01   F   CH4-CHS gDNA   ctc aag ... ... ... ... aag ggc agg ctc acc ctc acc tgc ctg atc cag aac ttc ttt
                                                                                                                       
  U96100   IGHE*01   F   CH4-CHS cDNA   --- --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                       
  AB699688 IGHE*01   F   CH4-CHS gDNA   --- --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P           A   D   I   S   V   L   W   L   R   N   D   A   P   V   Q   A   D 
  AB699687 IGHE*01   F   CH4-CHS gDNA   ccc ... ... gcg gac atc tct gtg ctg tgg ctg cgg aac gac gcc ccg gtg cag gca gac
                                                                                                                       
  U96100   IGHE*01   F   CH4-CHS cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                       
  AB699688 IGHE*01   F   CH4-CHS gDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                             R   H   S   T   T   R   P   H   K   A   S   D   S                   L   P 
  AB699687 IGHE*01   F   CH4-CHS gDNA   ... cgg cac tcc acc acc agg ccc cac aag gcc agc gac tcc ... ... ... ... ctc ccc
                                                                                                                       
  U96100   IGHE*01   F   CH4-CHS cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
                                                                                                                       
  AB699688 IGHE*01   F   CH4-CHS gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                         S   F   F   V   Y   S   R   L   V   V   S   Q   S   D   W               E   Q 
  AB699687 IGHE*01   F   CH4-CHS gDNA   tcc ttc ttc gtc tac agc cgc ctg gtg gtc agc cag tcc gac tgg ... ... ... gag cag
                                                                                                                       
  U96100   IGHE*01   F   CH4-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---
                                                                                                                       
  AB699688 IGHE*01   F   CH4-CHS gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         N   K   F   A   C   E   V   I   H   E   A   L   P   G   S   R   T   L   Q   K 
  AB699687 IGHE*01   F   CH4-CHS gDNA   aac aaa ttt gcc tgc gag gtg atc cac gag gca ctg ccc ggc tct agg acc ctc cag aaa
                                                                                                                       
  U96100   IGHE*01   F   CH4-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                       
  AB699688 IGHE*01   F   CH4-CHS gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                            __CHS___
                                        
                                        120 121 122 123 124 125 126 127 128 129 130 
                                         E   V   S   K   N   P               G   K  
  AB699687 IGHE*01   F   CH4-CHS gDNA   gag gtg tcc aaa aac ccc ... ... ... ggt aaa 
                                                                                    
  U96100   IGHE*01   F   CH4-CHS cDNA   --- --- --- --- --- --- ... ... ... --- --- 
                                                                                    
  AB699688 IGHE*01   F   CH4-CHS gDNA   --- --- --- --- --- --- ... ... ... --- --- 




                                   
                                   
                                    1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                    E   L   A   L   E   D   L   C   A   E   E   A   E   S   Q   E   L   E   A   M 
  AB699687 IGHE*01   F   M1 gDNA   gag ctg gcc ctg gag gac ctg tgt gcg gag gag gcc gag agc cag gag ctg gag gcc atg
                                                                                                                  
  AB699688 IGHE*01   F   M1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                   
                                   
                                    21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                    W   T   G   L   L   V   F   T   T   L   F   L   L   S   V   S   Y   G   A   A 
  AB699687 IGHE*01   F   M1 gDNA   tgg acg ggc ctc ctc gtc ttc acc acg ctc ttc ctg ctc agc gtg agc tac ggt gct gcc
                                                                                                                  
  AB699688 IGHE*01   F   M1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                   
                                   
                                    41  42  43  44  45 
                                    I   T   L   C   K  
  AB699687 IGHE*01   F   M1 gDNA   atc acc ctc tgc aag 
                                                       
  AB699688 IGHE*01   F   M1 gDNA   --- --- --- --- --- 




                                   
                                   
                                    1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                    V   K   W   V   L   A   A   I   L   Q   E   Q   P   P   A   S   H   D   Y   T 
  AB699687 IGHE*01   F   M2 gDNA   gtg aaa tgg gtc ctg gcc gcc atc ctg cag gag cag ccc cca gcc tcc cat gac tac acc
                                                                                                                  
  AB699688 IGHE*01   F   M2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                   
                                   
                                    21  22  23  24  25  26  27 
                                    N   V   Q   E   P   A   A  
  AB699687 IGHE*01   F   M2 gDNA   aac gtc cag gag ccg gct gcc 
                                                               
  AB699688 IGHE*01   F   M2 gDNA   --- --- --- --- --- --- --- 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
17/09/2014
Last updated:
27/05/2016
Authors:
Saida Saljoqi