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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                    
                                     
                                     1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                      A   P   K   T   A   P   S   V   Y   P   L   A   P   C   G   R 
  AB699686 IGHG1*01   F   CH1 gDNA                   gcc ccc aag acg gcc cca tcg gtc tac cct ctg gcc ccc tgc ggc agg
                                                      T                                                             
  M81770   IGHG1*02   F   CH1 cDNA                   a-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  U03778   IGHG1*03   F   CH1 cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
 

                                                 _____AB_____                                            ____________
                                                 15.1    15.3                                                        
                                      13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                      D   T   S               G   P   N   V   A   L   G   C   L   A   S   S   Y   F 
  AB699686 IGHG1*01   F   CH1 gDNA   gac acg tct ... ... ... ggc cct aac gtg gcc ttg ggc tgc ctg gcc tca agc tac ttc
                                                                                                                    
  M81770   IGHG1*02   F   CH1 cDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                          V                                                                         
  U03778   IGHG1*03   F   CH1 cDNA   --- gt- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  EU263977 IGHG1*04   P   CH1 gDNA                                    -- --- --- --- --- --- --- --- --- --- --- ---


                                     _______BC___________________                            _____________CD_________
                                                                                             45.1    45.3    45.5    
                                      30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                      P           E   P   V   T   M   T   W   N   S   G   A   L   T   S             
  AB699686 IGHG1*01   F   CH1 gDNA   ccc ... ... gag cca gtg acc atg acc tgg aac tcg ggc gcc ctg acc agt ... ... ...
                                                                                                                    
  M81770   IGHG1*02   F   CH1 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                                                                  V                                                 
  U03778   IGHG1*03   F   CH1 cDNA   --- ... ... --- --- --- --- g-- --- --- --- --- --- --- --- --- --- ... ... ...
                                                                  V                                                 
  EU263977 IGHG1*04   P   CH1 gDNA   --- ... ... --- --- --- --- g-- --- --- --- --- --- --- --- --- --- ... ... ...


                                     ____                                ___________________________DE_______________
                                     45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                          77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          G   V   H   T   F   P   S   V   L   Q   P   S                           G 
  AB699686 IGHG1*01   F   CH1 gDNA   ... ggc gtg cat acc ttc cca tcc gtc ctg cag ccg tca ... ... ... ... ... ... ggg
                                                                                                                    
  M81770   IGHG1*02   F   CH1 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                                                                                    
  U03778   IGHG1*03   F   CH1 cDNA   ... --- --- --c --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                                                                                    
  EU263977 IGHG1*04   P   CH1 gDNA   ... --- --- --c --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                     ____________                                                ___EF___            
                                         85.2                                                    96.1                
                                     85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                      L   Y   S   L   S   S   M   V   T   V   P   A   S   S   L               S   S 
  AB699686 IGHG1*01   F   CH1 gDNA   ctc tac tcc ctc agc agc atg gtg acc gtg ccg gcc agc agc ctg ... ... ... tcc agc
                                                                                                                    
  M81770   IGHG1*02   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---
                                                                                                                    
  U03778   IGHG1*03   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---
                                                                                                                    
  EU263977 IGHG1*04   P   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---


                                                         _________________________FG_________________________        
                                     
                                     100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                      K   S   Y   T   C   N   V   N   H   P   A           T   T   T   K   V   D   K 
  AB699686 IGHG1*01   F   CH1 gDNA   aag agc tac acc tgc aat gtc aac cac ccg gcc ... ... acc acc acc aag gtg gac aag
                                                                                                  P                 
  M81770   IGHG1*02   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --a c-- --- --- --- ---
                                                                                                                    
  U03778   IGHG1*03   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                                                                                                    
  EU263977 IGHG1*04   P   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                             
                                     
                                     120 121 
                                      R   V  
  AB699686 IGHG1*01   F   CH1 gDNA   cgt gtt 
                                             
  M81770   IGHG1*02   F   CH1 cDNA   --- --- 
                                             
  U03778   IGHG1*03   F   CH1 cDNA   --- --- 
                                             
  EU263977 IGHG1*04   P   CH1 gDNA   --- --- 



                                
                                    1   2   3   4   5   6   7   8   9   10  11  12 
                                    G   T   K   T   K   P   P   C   P   I   C   P  
  AB699686 IGHG1*01   F   H gDNA   gga aca aag acc aaa cca cca tgt ccc ata tgc cca 
                                                                                   
  M81770   IGHG1*02   F   H cDNA   --- --- --- --- --- --- --- --- --- --- --- --- 
                                        I   H   Q   P   Q   T                      
  U03778   IGHG1*03   F   H cDNA   --- -t- c-c cag ccg -a- a-- --- --- --- --- --- 




                                                                                                                    
                                     
                                     1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                  G   C   E   V   A   G   P   S   V   F   I   F   P   P   K   P   K 
  AB699686 IGHG1*01   F   CH2 gDNA               ggc tgt gaa gtg gcc ggg ccc tcg gtc ttc atc ttc cct cca aaa ccc aag
                                                                                                                    
  M81770   IGHG1*02   F   CH2 cDNA               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  U03778   IGHG1*03   F   CH2 cDNA               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                  A               P                                                 
  EU263977 IGHG1*04   P   CH2 gDNA               -c- --- --- --- c-- --- --- --- --- --- --- --- --- --- --- --- ---


                                                 _____AB_____                                            ____________
                                                 15.1    15.3                                                        
                                      13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                      D   T   L   M   I       S   Q   T   P   E   V   T   C   V   V   V   D   V   S 
  AB699686 IGHG1*01   F   CH2 gDNA   gac acc ctc atg atc ... tcc cag acc ccc gag gtc acg tgc gtg gtg gtg gac gtc agc
                                                                                                                    
  M81770   IGHG1*02   F   CH2 cDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  U03778   IGHG1*03   F   CH2 cDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                  R           Q                                     
  EU263977 IGHG1*04   P   CH2 gDNA   --- --- --- --- --- ... --- -g- --- --- c-- --- --- --- --- --- --- --t --- ---


                                     _______BC___________________                            _____________CD_________
                                                                                             45.1    45.3    45.5    
                                      30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                      K   E   H   A   E   V   Q   F   S   W   Y   V   D   G   V   E   V   H         
  AB699686 IGHG1*01   F   CH2 gDNA   aag gag cac gcc gag gtc cag ttc tcc tgg tac gtg gac ggc gta gag gtg cac ... ...
                                                                                                                    
  M81770   IGHG1*02   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...
                                                                                                                    
  U03778   IGHG1*03   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...
                                      Q           P                                                                 
  EU263977 IGHG1*04   P   CH2 gDNA   c-- --- --- c-g --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...


                                     ____                                ___________________________DE_______________
                                     45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                          77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          T   A   E   T   R   P   K   E   E   Q   F   N                           S 
  AB699686 IGHG1*01   F   CH2 gDNA   ... acg gcc gag acg aga cca aag gag gag cag ttc aac ... ... ... ... ... ... agc
                                                                                                                    
  M81770   IGHG1*02   F   CH2 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                                                                                    
  U03778   IGHG1*03   F   CH2 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                  Q                                                                 
  EU263977 IGHG1*04   P   CH2 gDNA   ... --- --- c-- --- --g --- --- --- --- --- -.- --- ... ... ... ... ... ... ---


                                     ____________                                                ___EF___            
                                         85.2                                                    96.1                
                                     85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                      T   Y   R   V   V   S   V   L   P   I   Q   H   Q   D   W           L   K   G 
  AB699686 IGHG1*01   F   CH2 gDNA   acc tac cgt gtg gtc agc gtc ctg ccc atc cag cac cag gac tgg ... ... ctg aag ggg
                                                                                                                    
  M81770   IGHG1*02   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                                    
  U03778   IGHG1*03   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                         
  EU263977 IGHG1*04   P   CH2 gDNA   --- -


                                                         _________________________FG_________________________        
                                     
                                     100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                      K   E   F   K   C   K   V   N   N   V   D           L   P   A   P   I   T   R 
  AB699686 IGHG1*01   F   CH2 gDNA   aag gag ttc aag tgc aag gtc aac aac gta gac ... ... ctc cca gcc ccc atc acg agg
                                                                                                                    
  M81770   IGHG1*02   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                                                                                                    
  U03778   IGHG1*03   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                                             
                                     
                                     120 121 122 123 124 125 
                                      T   I   S   K   A   I  
  AB699686 IGHG1*01   F   CH2 gDNA   acc atc tcc aag gct ata 
                                                             
  M81770   IGHG1*02   F   CH2 cDNA   --- --- --- --- --- --- 
                                                             
  U03778   IGHG1*03   F   CH2 cDNA   --- --- --- --- --- --- 






                                                                                                                         
                                         
                                         1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                          G   Q   S   R   E   P   Q   V   Y   T   L   P   P   P   A   E 
  AB699686 IGHG1*01   F   CH3-CHS gDNA                   ggg cag agc cgg gag ccg cag gtg tac acc ctg ccc cca ccc gcc gag
                                                                                                                        
  M81770   IGHG1*02   F   CH3-CHS cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                        
  U03778   IGHG1*03   F   CH3-CHS cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                     _____AB_____                                            ____________
                                                     15.1    15.3                                                        
                                          13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                          E   L   S               R   S   K   V   T   V   T   C   L   V   I   G   F   Y 
  AB699686 IGHG1*01   F   CH3-CHS gDNA   gag ctg tcc ... ... ... agg agc aaa gtc acc gta acc tgc ctg gtc att ggc ttc tac
                                                                                                                        
  M81770   IGHG1*02   F   CH3-CHS cDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                      L                                 
  U03778   IGHG1*03   F   CH3-CHS cDNA   --- --- --- ... ... ... --- --- --- --- --g c-- --- --- --- --- --- --- --- ---


                                         _______BC___________________                            _____________CD_________
                                                                                                 45.1    45.3    45.5    
                                          30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                          P           P   D   I   H   V   E   W   K   S   N   G   Q   P   E   P   E   G 
  AB699686 IGHG1*01   F   CH3-CHS gDNA   cca ... ... cct gac atc cat gtt gag tgg aag agc aac gga cag ccg gag cca gag ggc
                                                                                                                        
  M81770   IGHG1*02   F   CH3-CHS cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                      N 
  U03778   IGHG1*03   F   CH3-CHS cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- aa-


                                         ____                                ___________________________DE_______________
                                         45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                              77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                              N   Y   R   T   T   P   P   Q   Q   D   V   D                           G 
  AB699686 IGHG1*01   F   CH3-CHS gDNA   ... aat tac cgc acc acc ccg ccc cag cag gac gtg gac ... ... ... ... ... ... ggg
                                                                                                                        
  M81770   IGHG1*02   F   CH3-CHS cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                              T                                                                         
  U03778   IGHG1*03   F   CH3-CHS cDNA   ... -ca --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                         ____________                                                ___EF___            
                                             85.2                                                    96.1                
                                         85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                          T   F   F   L   Y   S   K   L   A   V   D   K   A   R   W           D   H   G 
  AB699686 IGHG1*01   F   CH3-CHS gDNA   acc ttc ttc ctg tac agc aag ctc gcg gtg gac aag gca aga tgg ... ... gac cat gga
                                                                                                                        
  M81770   IGHG1*02   F   CH3-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                                        
  U03778   IGHG1*03   F   CH3-CHS cDNA   --- --- --- --- --- --- --a --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                             _________________________FG_________________________        
                                         
                                         100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                          E   T   F   E   C   A   V   M   H   E   A       L   H   N   H   Y   T   Q   K 
  AB699686 IGHG1*01   F   CH3-CHS gDNA   gaa aca ttt gag tgt gcg gtg atg cac gag gct ... ctg cac aac cac tac acc cag aag
                                                                                                          D             
  M81770   IGHG1*02   F   CH3-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- g-- --- --- ---
                                          D   K                                                                         
  U03778   IGHG1*03   F   CH3-CHS cDNA   --c -a- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- ---


                                                                             __CHS___
                                         
                                         120 121 122 123 124 125 126 127 128 129 130 
                                          S   I   S   K   T   Q               G   K  
  AB699686 IGHG1*01   F   CH3-CHS gDNA   tcc atc tcc aag act cag ... ... ... ggt aaa 
                                                                                     
  M81770   IGHG1*02   F   CH3-CHS cDNA   --- --- --- --- --- --- ... ... ... --- --- 
                                                                                     
  U03778   IGHG1*03   F   CH3-CHS cDNA   --- --- --- --- --- --- ... ... ... --- --- 



                                    
                                    
                                     1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                     E   L   L   L   E   E   S   C   A   D   A   Q   D   G   E   L   D   G   L   W 
  AB699686 IGHG1*01   F   M1 gDNA   gaa ctg ctc ctg gag gag agc tgt gcc gac gcc cag gac ggg gag ctg gac ggg ctc tgg


                                    
                                    
                                     21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                     T   T   I   S   I   F   I   T   L   F   L   L   S   V   C   Y   S   A   T   V 
  AB699686 IGHG1*01   F   M1 gDNA   acc acc atc tcc atc ttc atc acg ctc ttc ctg ctc agc gtg tgc tac agc gcc acc gtg


                                    
                                    
                                     41  42  43  44 
                                     T   L   F   K  
  AB699686 IGHG1*01   F   M1 gDNA   acg ctc ttc aag 





                                   
                                    
                                     1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                     V   K   W   I   F   S   S   V   V   E   L   K   R   T   I   V   P   D   Y   R 
  AB699686 IGHG1*01   F   M2 gDNA   gtg aag tgg atc ttc tcg tcg gtg gtg gag ctg aag cgg acc att gtc ccc gac tac aga


                                    
                                    
                                     21  22  23  24  25  26  27 
                                     N   M   I   G   Q   G   A  
  AB699686 IGHG1*01   F   M2 gDNA   aac atg atc ggg cag ggg gcc 



This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
17/09/2014
Last updated:
27/05/2016
Authors:
Saida Saljoqi