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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                     
                                     
                                     1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                      A   Y   N   T   A   P   S   V   Y   P   L   A   P   C   G   R 
  AB699686 IGHG3*01   F   CH1 gDNA                   gcc tac aac aca gct cca tcg gtc tac cct ctg gcc ccc tgt ggc agg
                                                                                                                    
  AB513625 IGHG3*02   F   CH1 gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  EU372658 IGHG3*03   F   CH1 gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                 _____AB_____                                            ____________
                                                 15.1    15.3                                                        
                                      13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                      D   V   S               D   H   N   V   A   L   G   C   L   V   S   S   Y   F 
  AB699686 IGHG3*01   F   CH1 gDNA   gac gtg tct ... ... ... gat cat aac gtg gcc ttg ggc tgc ctg gtc tca agc tac ttc
                                                                                                                    
  AB513625 IGHG3*02   F   CH1 gDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  EU372658 IGHG3*03   F   CH1 gDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --t --- --- --- --- ---


                                     _______BC___________________                            _____________CD_________
                                                                                             45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                      P           E   P   V   T   V   T   W   N   S   G   A   L   S   R             
  AB699686 IGHG3*01   F   CH1 gDNA   ccc ... ... gag cca gtg acc gtg acc tgg aac tcg ggt gcc ctg tcc aga ... ... ...
                                                                                                                    
  AB513625 IGHG3*02   F   CH1 gDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                                                                                                                    
  EU372658 IGHG3*03   F   CH1 gDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                     ____                                ___________________________DE_______________
                                     45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                          77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          V   V   H   T   F   P   S   V   L   Q   P   S                           G 
  AB699686 IGHG3*01   F   CH1 gDNA   ... gtc gtg cat acc ttc cca tct gtc ctg cag ccg tca ... ... ... ... ... ... ggg
                                                                                                                    
  AB513625 IGHG3*02   F   CH1 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                                                                                    
  EU372658 IGHG3*03   F   CH1 gDNA   ... --- --- --- --- --- --- --c --- --- --- --- --- ... ... ... ... ... ... ---


                                     ____________                                                ___EF___            
                                         85.2                                                    96.1                
                                     85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                      L   Y   S   L   S   S   M   V   I   V   A   A   S   S   L               S   T 
  AB699686 IGHG3*01   F   CH1 gDNA   ctc tac tcc ctc agc agc atg gtg atc gtg gcg gcc agc agc ctg ... ... ... tcc acc
                                                                                                                    
  AB513625 IGHG3*02   F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---
                                                                                                                    
  EU372658 IGHG3*03   F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---


                                                         _________________________FG_________________________        
                                     
                                     100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                      L   S   Y   T   C   N   V   Y   H   P   A           T   N   T   K   V   D   K 
  AB699686 IGHG3*01   F   CH1 gDNA   ctg agc tac acg tgc aac gtc tac cac ccg gcc ... ... acc aac acc aag gtg gac aag
                                                                                                                    
  AB513625 IGHG3*02   F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                                                                                                    
  EU372658 IGHG3*03   F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                             
                                     
                                     120 121 
                                      R   V  
  AB699686 IGHG3*01   F   CH1 gDNA   cgt gtt 
                                             
  AB513625 IGHG3*02   F   CH1 gDNA   --- --- 
                                             
  EU372658 IGHG3*03   F   CH1 gDNA   --- --- 



                                   
                                   
                                    1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16 
                                    D   I   E   P   P   T   P   I   C   P   E   I   C   S   C   P  
  AB699686 IGHG3*01   F   H gDNA   gac atc gaa ccc ccc aca ccc atc tgt ccc gaa att tgc tca tgc cca 
                                                                                                   
  AB513625 IGHG3*02   F   H gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 
                                                                                                   
  EU372658 IGHG3*03   F   H gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 




                                                                                                                     
                                     
                                     1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                              A   A   E   V   L   G   A   P   S   V   F   L   F   P   P   K   P   K 
  AB699686 IGHG3*01   F   CH2 gDNA           gct gca gag gtc ctg gga gca ccg tcg gtc ttc ctc ttc cct cca aaa ccc aag
                                                                                                                    
  AB513625 IGHG3*02   F   CH2 gDNA           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  EU372658 IGHG3*03   F   CH2 gDNA           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                 _____AB_____                                            ____________
                                                 15.1    15.3                                                        
                                      13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                      D   I   L   M   I       S   R   T   P   K   V   T   C   V   V   V   D   V   S 
  AB699686 IGHG3*01   F   CH2 gDNA   gac atc ctc atg atc ... tcc cgg aca ccc aag gtc acg tgc gtg gtg gtg gac gtg agc
                                                                                                                    
  AB513625 IGHG3*02   F   CH2 gDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  EU372658 IGHG3*03   F   CH2 gDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                     _______BC___________________                            _____________CD_________
                                                                                             45.1    45.3    45.5    
                                      30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                      Q   E   E   A   E   V   Q   F   S   W   Y   V   D   G   V   Q   L   Y         
  AB699686 IGHG3*01   F   CH2 gDNA   cag gag gag gct gaa gtc cag ttc tcc tgg tac gtg gac ggc gta cag ttg tac ... ...
                                                                                                                    
  AB513625 IGHG3*02   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...
                                                                                                                    
  EU372658 IGHG3*03   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...


                                     ____                                ___________________________DE_______________
                                     45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                          77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          T   A   Q   T   R   P   M   E   E   Q   F   N                           S 
  AB699686 IGHG3*01   F   CH2 gDNA   ... acg gcc cag acg agg cca atg gag gag cag ttc aac ... ... ... ... ... ... agc
                                                                                                                    
  AB513625 IGHG3*02   F   CH2 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                                                                                    
  EU372658 IGHG3*03   F   CH2 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                     ____________                                                ___EF___            
                                         85.2                                                    96.1                
                                     85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                      T   Y   R   V   V   S   V   L   P   I   Q   H   Q   D   W           L   K   G 
  AB699686 IGHG3*01   F   CH2 gDNA   acc tac cgc gtg gtc agc gtc ctg ccc atc cag cac cag gac tgg ... ... ctg aag ggg
                                                                                                                    
  AB513625 IGHG3*02   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                                    
  EU372658 IGHG3*03   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                         _________________________FG_________________________        
                                     
                                     100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                      K   E   F   K   C   K   V   N   N   K   D           L   L   S   P   I   T   R 
  AB699686 IGHG3*01   F   CH2 gDNA   aag gag ttc aag tgc aag gtc aac aac aaa gac ... ... ctc ctt tcc ccc atc acg agg
                                                                                                                    
  AB513625 IGHG3*02   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                                                                                                    
  EU372658 IGHG3*03   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                                             
                                     
                                     120 121 122 123 124 125 
                                      T   I   S   K   A   T  
  AB699686 IGHG3*01   F   CH2 gDNA   acc atc tcc aag gct aca 
                                                             
  AB513625 IGHG3*02   F   CH2 gDNA   --- --- --- --- --- --- 
                                                             
  EU372658 IGHG3*03   F   CH2 gDNA   --- --- --- --- --- --- 




                                                                                                                        
                                         
                                         1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                          G   P   S   R   V   P   Q   V   Y   T   L   P   P   A   W   E 
  AB699686 IGHG3*01   F   CH3-CHS gDNA                   ggg ccg agc cgg gtg ccg cag gtg tac acc ctg ccc cca gcc tgg gaa
                                                                                                                        
  AB513625 IGHG3*02   F   CH3-CHS gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                        
  EU372658 IGHG3*03   F   CH3-CHS gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                     _____AB_____                                            ____________
                                                     15.1    15.3                                                        
                                          13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                          E   L   S               K   S   K   V   S   I   T   C   L   V   T   G   F   Y 
  AB699686 IGHG3*01   F   CH3-CHS gDNA   gag ctg tcc ... ... ... aag agc aaa gtc agc ata acc tgc ctg gtc act ggc ttc tac
                                                                                                                        
  AB513625 IGHG3*02   F   CH3-CHS gDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                        
  EU372658 IGHG3*03   F   CH3-CHS gDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                         _______BC___________________                            _____________CD_________
                                                                                                 45.1    45.3    45.5    
                                          30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                          P           P   D   I   D   V   E   W   Q   S   N   G   Q   Q   E   P   E   G 
  AB699686 IGHG3*01   F   CH3-CHS gDNA   cca ... ... cct gac atc gat gtc gag tgg cag agc aac gga caa caa gag cca gag ggc
                                                                                                                        
  AB513625 IGHG3*02   F   CH3-CHS gDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                        
  EU372658 IGHG3*03   F   CH3-CHS gDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                         ____                                ___________________________DE_______________
                                         45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                              77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                              N   Y   R   T   T   P   P   Q   Q   D   V   D                           G 
  AB699686 IGHG3*01   F   CH3-CHS gDNA   ... aat tac cgc acc acc ccg ccc cag cag gac gtg gat ... ... ... ... ... ... ggg
                                                                                                                        
  AB513625 IGHG3*02   F   CH3-CHS gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                                                                                        
  EU372658 IGHG3*03   F   CH3-CHS gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                         ____________                                                ___EF___            
                                             85.2                                                    96.1                
                                         85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                          T   Y   F   L   Y   S   K   L   A   V   D   K   V   R   W           Q   R   G 
  AB699686 IGHG3*01   F   CH3-CHS gDNA   acc tac ttc ctg tac agc aag ctc gcg gtg gac aag gtc agg tgg ... ... cag cgt gga
                                                                                                                        
  AB513625 IGHG3*02   F   CH3-CHS gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                                        
  EU372658 IGHG3*03   F   CH3-CHS gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                             _________________________FG_________________________        
                                         
                                         100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                          D   L   F   Q   C   A   V   M   H   E   A       L   H   N   H   Y   T   Q   K 
  AB699686 IGHG3*01   F   CH3-CHS gDNA   gac cta ttc cag tgt gcg gtg atg cac gag gct ... ctg cac aac cac tac acc cag aag
                                                                                                                        
  AB513625 IGHG3*02   F   CH3-CHS gDNA   --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- ---
                                                                                                                        
  EU372658 IGHG3*03   F   CH3-CHS gDNA   --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- ---


                                                                             __CHS___
                                         
                                         120 121 122 123 124 125 126 127 128 129 130 
                                          S   V   S   Q   T   P               G   K  
  AB699686 IGHG3*01   F   CH3-CHS gDNA   tcc gtc tcc cag act ccg ... ... ... ggt aaa 
                                                                                     
  AB513625 IGHG3*02   F   CH3-CHS gDNA   --- --- --- --- --- --- ... ... ... --- --- 
                                              I       K       Q                      
  EU372658 IGHG3*03   F   CH3-CHS gDNA   --- a-- --- a-- --- -a- ... ... ... --- --- 



                                    
                                    
                                     1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                     E   L   L   L   E   E   S   C   A   D   A   Q   D   G   E   L   D   G   L   W 
  AB699686 IGHG3*01   F   M1 gDNA   gaa ctg ctc ctg gag gag agc tgt gcc gac gcc cag gac ggg gag ctg gac ggg ctc tgg
                                                                                                                   
  AB513625 IGHG3*02   F   M1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                    
                                    
                                     21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                     T   T   I   S   I   F   I   T   L   F   L   L   S   V   C   Y   S   A   T   V 
  AB699686 IGHG3*01   F   M1 gDNA   acc acc atc tcc atc ttc atc acg ctc ttc ctg ctc agc gtg tgc tac agc gcc acc gtg
                                                                                                                   
  AB513625 IGHG3*02   F   M1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                    
                                    
                                     41  42  43  44 
                                     T   L   F   K  
  AB699686 IGHG3*01   F   M1 gDNA   acg ctc ttc aag 
                                                    
  AB513625 IGHG3*02   F   M1 gDNA   --- --- --- --- 



                                   
                                    
                                     1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                     V   K   W   I   F   S   P   V   V   E   L   K   R   T   I   V   P   D   Y   R 
  AB699686 IGHG3*01   F   M2 gDNA   gtg aag tgg atc ttc tcg ccg gtg gtg gag ctg aag cgg acc att gtc ccc gac tac aga
                                                             S                                                     
  AB513625 IGHG3*02   F   M2 gDNA   --- --- --- --- --- --- t-- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                    
                                    
                                     21  22  23  24  25  26  27 
                                     N   M   I   G   Q   G   A  
  AB699686 IGHG3*01   F   M2 gDNA   aac atg atc ggg cag ggg gcc 
                                                                
  AB513625 IGHG3*02   F   M2 gDNA   --- --- --- --- --- --- --- 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
17/09/2014
Last updated:
27/05/2016
Authors:
Saida Saljoqi