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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                       
                                       
                                       1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                        A   P   K   T   A   P   S   V   Y   P   L   A   P   C   S   R 
  AB699686 IGHG5-2*01   F   CH1 gDNA                   gcc ccc aag acg gcc cca tcg gtc tac cct ctg gcc ccc tgc agc agg
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH1 gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                      
  EU372657 IGHG5-2*02   F   CH1 gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                   _____AB_____                                            ____________
                                                   15.1    15.3                                                        
                                        13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                        D   T   S               G   P   N   V   A   L   G   C   L   V   S   S   Y   F 
  AB699686 IGHG5-2*01   F   CH1 gDNA   gac acg tct ... ... ... ggc cct aac gtg gcc ttg ggc tgc ctg gtc tca agc tac ttc
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH1 gDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                      
  EU372657 IGHG5-2*02   F   CH1 gDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                       _______BC___________________                            _____________CD_________
                                                                                               45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                        P           E   L   V   T   V   T   W   N   S   G   A   L   T   S             
  AB699686 IGHG5-2*01   F   CH1 gDNA   ccc ... ... gag cta gtg acc gtg acc tgg aac tcg ggc gcc ctg acc agt ... ... ...
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH1 gDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                                                        P                                                             
  EU372657 IGHG5-2*02   F   CH1 gDNA   --- ... ... --- -c- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                       ____                                ___________________________DE_______________
                                       45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                            77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                            G   V   H   T   F   P   S   V   L   Q   P   S                           G 
  AB699686 IGHG5-2*01   F   CH1 gDNA   ... ggc gtg cac acc ttc cca tcc gtc ctg cag ccg tca ... ... ... ... ... ... ggg
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH1 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                                                                                      
  EU372657 IGHG5-2*02   F   CH1 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                       ____________                                                ___EF___            
                                           85.2                                                    96.1                
                                       85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                        L   Y   S   L   S   S   M   V   T   V   P   A   H   S   L               S   S 
  AB699686 IGHG5-2*01   F   CH1 gDNA   ctc tac tcc ctc agc agc atg gtg acc gtg ccg gcc cac agc ttg ... ... ... tcc agc
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---
                                                                                                                      
  EU372657 IGHG5-2*02   F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---


                                                           _________________________FG_________________________        
                                       
                                       100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                        K   R   Y   T   C   N   V   N   H   P   A           T   K   T   K   V   D   L 
  AB699686 IGHG5-2*01   F   CH1 gDNA   aag cgc tat acg tgc aat gtc aac cac cca gcc ... ... acc aaa acc aag gtg gac ctg
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                                                                                                      
  EU372657 IGHG5-2*02   F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                               
                                       
                                       120 121 
                                        C   V  
  AB699686 IGHG5-2*01   F   CH1 gDNA   tgt gtt 
                                               
  AB699687 IGHG5-2*01   F   CH1 gDNA   --- ---  
                                               
  EU372657 IGHG5-2*02   F   CH1 gDNA   --- --- 




                                    
                                      1   2   3   4   5   6   7   8  
                                      G   R   P   C   P   I   C   P  
  AB699686 IGHG5-2*01   F   H gDNA   gga cga cca tgt ccc ata tgc cca 
                                                                     
  AB699687 IGHG5-2*01   F   H gDNA   --- --- --- --- --- --- --- --- 
                                                                     
  EU372657 IGHG5-2*02   F   H gDNA   --- --- --- --- --- --- --- --- 





                                                                                                                       
                                       
                                       1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                    G   C   E   V   A   G   P   S   V   F   I   F   P   P   K   P   K 
  AB699686 IGHG5-2*01   F   CH2 gDNA               ggc tgt gaa gtg gcc ggg ccc tcg gtc ttc atc ttc cct cca aaa ccc aag
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH2 gDNA               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                      
  EU372657 IGHG5-2*02   F   CH2 gDNA               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                   _____AB_____                                            ____________
                                                   15.1    15.3                                                        
                                        13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                        D   I   L   M   I       S   R   T   P   E   V   T   C   V   V   V   D   V   S 
  AB699686 IGHG5-2*01   F   CH2 gDNA   gac atc ctc atg atc ... tcc cgg acc ccc gag gtc acg tgc gtg gtg gtg gac gtc agc
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH2 gDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                      
  EU372657 IGHG5-2*02   F   CH2 gDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                       _______BC___________________                            _____________CD_________
                                                                                               45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                        K   E   H   A   E   V   Q   F   S   W   Y   V   D   G   V   E   V   H         
  AB699686 IGHG5-2*01   F   CH2 gDNA   aag gag cac gcc gag gtc cag ttc tcc tgg tac gtg gac ggc gta gag gtg cac ... ...
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...
                                                                                                E                     
  EU372657 IGHG5-2*02   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- -a- --- --- --- ... ...


                                       ____                                ___________________________DE_______________
                                       45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                            77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                            T   A   E   T   R   P   K   E   E   Q   F   N                           S 
  AB699686 IGHG5-2*01   F   CH2 gDNA   ... acg gcc gag acg aga cca aag gag gag cag ttc aac ... ... ... ... ... ... agc
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH2 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                                                                                      
  EU372657 IGHG5-2*02   F   CH2 gDNA   ... --- --- --- --- --g --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                       ____________                                                ___EF___            
                                           85.2                                                    96.1                
                                       85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                        T   Y   R   V   V   S   V   L   P   I   Q   H   E   D   W           L   K   G 
  AB699686 IGHG5-2*01   F   CH2 gDNA   acc tac cgt gtg gtc agc gtc ctg ccc atc cag cac gag gac tgg ... ... ctg aag ggg
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                                      
  EU372657 IGHG5-2*02   F   CH2 gDNA   --- --- --c --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                           _________________________FG_________________________        
                                       
                                       100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                        K   E   F   E   C   K   V   N   N   E   D           L   P   G   P   I   T   R 
  AB699686 IGHG5-2*01   F   CH2 gDNA   aag gag ttc gag tgc aag gtc aac aac gaa gac ... ... ctc cca ggc ccc atc acg agg
                                                                                                                      
  AB699687 IGHG5-2*01   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                                                                                                      
  EU372657 IGHG5-2*02   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                                               
                                       
                                       120 121 122 123 124 125 
                                        T   I   S   K   A   K  
  AB699686 IGHG5-2*01   F   CH2 gDNA   acc atc tcc aag gcc aaa 
                                                               
  AB699687 IGHG5-2*01   F   CH2 gDNA   --- --- --- --- --- --- 
                                                               
  EU372657 IGHG5-2*02   F   CH2 gDNA   --- --- --- --- --- --- 





                                                                                                                           
                                           
                                           1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                            G   V   V   R   S   P   E   V   Y   T   L   P   P   P   A   E 
  AB699686 IGHG5-2*01   F   CH3-CHS gDNA                   ggg gtg gta cgg agc ccg gag gtg tac acc ctg ccc cca ccc gcc gag
                                                                                                                          
  AB699687 IGHG5-2*01   F   CH3-CHS gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                          
  EU372657 IGHG5-2*02   F   CH3-CHS gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                       _____AB_____                                            ____________
                                                       15.1    15.3                                                        
                                            13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                            E   L   S               K   S   K   V   T   L   T   C   L   V   K   S   F   F 
  AB699686 IGHG5-2*01   F   CH3-CHS gDNA   gag ctg tcc ... ... ... aag agc aaa gtc acg cta acc tgc ctg gtc aaa agc ttc ttc
                                                                                                                          
  AB699687 IGHG5-2*01   F   CH3-CHS gDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                            I                                       I     
  EU372657 IGHG5-2*02   F   CH3-CHS gDNA   --- --- --- ... ... ... --- --- -t- --- --- --- --- --- --- --- --- --- a-- ---


                                           _______BC___________________                            _____________CD_________
                                                                                                   45.1    45.3    45.5    
                                            30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                            P           P   F   I   H   V   G   W   K   I   N   G   Q   L   E   P   E   G 
  AB699686 IGHG5-2*01   F   CH3-CHS gDNA   ccg ... ... cct ttc atc cat gtt ggg tgg aaa atc aac gga cag ctg gag cca gag ggc
                                                                                                                          
  AB699687 IGHG5-2*01   F   CH3-CHS gDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                        X                   E                       K   P               N 
  EU372657 IGHG5-2*02   F   CH3-CHS gDNA   --- ... ... n-- --- --- --- --- -a- --- --- --- --- --- a-a -ca --- --- --- aa-


                                           ____                                ___________________________DE_______________
                                           45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                                77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                N   Y   H   T   T   P   P   Q   E   D   E   D                           G 
  AB699686 IGHG5-2*01   F   CH3-CHS gDNA   ... aat tac cac acc acc ccg ccc cag gag gac gag gac ... ... ... ... ... ... ggg
                                                                                                                          
  AB699687 IGHG5-2*01   F   CH3-CHS gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                                A       R                                                               R 
  EU372657 IGHG5-2*02   F   CH3-CHS gDNA   ... gca --t -g- --- --- --- --t --- --- --- --- --- ... ... ... ... ... ... a--


                                           ____________                                                ___EF___            
                                               85.2                                                    96.1                
                                           85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                            T   Y   F   L   Y   S   K   L   A   V   D   K   A   R   L               Q   S 
  AB699686 IGHG5-2*01   F   CH3-CHS gDNA   acc tac ttc ctg tac agc aaa ctc gcg gtg gac aag gcg agg ttg ... ... ... cag agt
                                                                                                                          
  AB699687 IGHG5-2*01   F   CH3-CHS gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---
                                                                                                    W           D   H   G 
  EU372657 IGHG5-2*02   F   CH3-CHS gDNA   --- --- --- --- --- --- --g --- --- --- --- --- --a --a -g- ... ... gac --t g-a


                                                               _________________________FG_________________________        
                                           
                                           100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                            G   G   I   H   C   A   V   M   H   E   A       L   H   N   H   Y   T   E   K 
  AB699686 IGHG5-2*01   F   CH3-CHS gDNA   gga ggc atc cac tgt gcg gtg atg cac gag gct ... ctg cac aac cac tac acc gag aag
                                                                                                                          
  AB699687 IGHG5-2*01   F   CH3-CHS gDNA   --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- ---
                                            E   T   F   E                                                           Q     
  EU372657 IGHG5-2*02   F   CH3-CHS gDNA   -a- aca t-t g-g --- --- --- --- --- --- --- ... --- --- --- --- --- --- c-- ---


                                                                               __CHS___
                                           
                                           120 121 122 123 124 125 126 127 128 129 130 
                                            S   V   S   L   T   P               G   K  
  AB699686 IGHG5-2*01   F   CH3-CHS gDNA   tcc gtc tcc ctg act ccg ... ... ... ggt aaa 
                                                                                       
  AB699687 IGHG5-2*01   F   CH3-CHS gDNA   --- --- --- --- --- --- ... ... ... --- --- 
                                                I       K       Q                      
  EU372657 IGHG5-2*02   F   CH3-CHS gDNA   --- a-- --- aa- --- -a- ... ... ... --- --- 




                                      
                                      
                                       1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                       E   L   L   L   E   E   S   C   A   D   A   Q   D   G   E   L   D   G   L   W 
  AB699686 IGHG5-2*01   F   M1 gDNA   gaa ctg ctc ctg gag gag agc tgt gcc gac gcc cag gac ggg gag ctg gac ggg ctc tgg
                                                                                                                     
  AB699687 IGHG5-2*01   F   M1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                      
                                      
                                       21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                       T   T   I   S   I   F   I   T   L   F   L   L   S   V   C   Y   S   A   T   V 
  AB699686 IGHG5-2*01   F   M1 gDNA   acc acc atc tcc atc ttc atc acg ctc ttc ctg ctc agc gtg tgc tac agc gcc acc gtg
                                                                                                                     
  AB699687 IGHG5-2*01   F   M1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                      
                                      
                                       41  42  43  44 
                                       T   L   F   K  
  AB699686 IGHG5-2*01   F   M1 gDNA   acg ctc ttc aag 
                                                      
  AB699687 IGHG5-2*01   F   M1 gDNA   --- --- --- --- 
                                      
                                      
                                       1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                       V   K   W   I   F   S   S   V   V   E   L   K   R   T   I   V   P   D   Y   R 
  AB699686 IGHG5-2*01   F   M2 gDNA   gtg aag tgg atc ttc tcg tcg gtg gtg gag ctg aag cgg acc att gtc ccc gac tac aga
                                                                                                                     
  AB699687 IGHG5-2*01   F   M2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                      
                                      
                                       21  22  23  24  25  26  27 
                                       N   M   I   G   Q   E   A  
  AB699686 IGHG5-2*01   F   M2 gDNA   aac atg atc gga cag gag gcc 
                                                                  
  AB699687 IGHG5-2*01   F   M2 gDNA   --- --- --- --- --- --- --- 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
17/09/2014
Last updated:
27/05/2016
Authors:
Saida Saljoqi