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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                      
                                       
                                       1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                        X   P   K   T   A   P   S   V   Y   P   L   A   P   C   G   R 
  AB699687 IGHG6-1*01   F   CH1 gDNA                   ncc ccc aag acg gcc cca tcg gtc tac cct ctg gcc ccc tgc ggc agg
                                                        A                                                             
  M81771   IGHG6-1*02   F   CH1 cDNA                   g-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                   _____AB_____                                            ____________
                                                   15.1    15.3                                                        
                                        13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                        D   T   S               G   P   N   V   A   L   G   C   L   A   S   S   Y   F 
  AB699687 IGHG6-1*01   F   CH1 gDNA   gac acg tct ... ... ... ggc cct aac gtg gcc ttg ggc tgc ctg gcc tca agc tac ttc
                                                                                                                      
  M81771   IGHG6-1*02   F   CH1 cDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                       _______BC___________________                            _____________CD_________
                                                                                               45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                        P           E   P   V   T   V   T   W   N   S   G   A   L   T   S             
  AB699687 IGHG6-1*01   F   CH1 gDNA   ccc ... ... gag cca gtg acc gtg acc tgg aac tcg ggc gcc ctg acc agt ... ... ...
                                                                                                                      
  M81771   IGHG6-1*02   F   CH1 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                       ____                                ___________________________DE_______________
                                       45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                            77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                            G   V   H   T   F   P   S   V   L   Q   P   S                           G 
  AB699687 IGHG6-1*01   F   CH1 gDNA   ... ggc gtg cac acc ttc cca tcc gtc ctg cag ccg tca ... ... ... ... ... ... ggg
                                                                                        A                             
  M81771   IGHG6-1*02   F   CH1 cDNA   ... --- --- --- --- --- --- --- --- --- --- --t g-- ... ... ... ... ... ... ---


                                       ____________                                                ___EF___            
                                           85.2                                                    96.1                
                                       85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                        L   Y   S   L   S   S   M   V   T   V   P   A   S   S   L               S   S 
  AB699687 IGHG6-1*01   F   CH1 gDNA   ctc tac tcc ctc agc agc atg gtg acc gtg ccg gcc agc agc ctg ... ... ... tcc agc
                                                                                                                      
  M81771   IGHG6-1*02   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---


                                                           _________________________FG_________________________        
                                       
                                       100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                        K   S   Y   T   C   N   V   N   H   P   A           T   T   T   K   V   D   K 
  AB699687 IGHG6-1*01   F   CH1 gDNA   aag agc tac acc tgc aat gtc aac cac ccg gcc ... ... acc acc acc aag gtg gac aag
                                                                                                                      
  M81771   IGHG6-1*02   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                               
                                       
                                       120 121 
                                        R   V  
  AB699687 IGHG6-1*01   F   CH1 gDNA   cgt gtt 
                                               
  M81771   IGHG6-1*02   F   CH1 cDNA   --- --- 
                                     
                                     
                                      1   2   3   4   5   6   7   8  
                                      G   R   P   C   P   I   C   P  
  AB699687 IGHG6-1*01   F   H gDNA   gga cga cca tgt ccc ata tgc cca 
                                                                     
  M81771   IGHG6-1*02   F   H cDNA   --- --- --- --- --- --- --- --- 
                                                                                                                       
                                       
                                       1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                    A   C   E   G   P   G   P   S   A   F   I   F   P   P   K   P   K 
  AB699687 IGHG6-1*01   F   CH2 gDNA               gcc tgt gaa ggg ccc ggg ccc tcg gcc ttc atc ttc cct cca aaa ccc aag
                                                                                                                      
  M81771   IGHG6-1*02   F   CH2 cDNA               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                   _____AB_____                                            ____________
                                                   15.1    15.3                                                        
                                        13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                        D   T   L   M   I       S   R   T   P   K   V   T   C   V   V   V   D   V   S 
  AB699687 IGHG6-1*01   F   CH2 gDNA   gac acc ctc atg atc ... tcc cgg acc ccc aag gtc acg tgc gtg gtg gtt gat gtg agc
                                                F                                                                     
  M81771   IGHG6-1*02   F   CH2 cDNA   --- --- t-- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                       _______BC___________________                            _____________CD_________
                                                                                               45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                        Q   E   N   P   E   V   Q   F   S   W   Y   V   D   G   V   E   V   H         
  AB699687 IGHG6-1*01   F   CH2 gDNA   cag gag aac ccg gag gtc cag ttc tcc tgg tac gtg gac ggc gta gag gtg cac ... ...
                                                                                                                      
  M81771   IGHG6-1*02   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...


                                       ____                                ___________________________DE_______________
                                       45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                            77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                            T   A   Q   T   R   P   K   E   E   Q   F   N                           S 
  AB699687 IGHG6-1*01   F   CH2 gDNA   ... acg gcc cag acg agg cca aag gag gag cag ttc aac ... ... ... ... ... ... agc
                                                                                                                      
  M81771   IGHG6-1*02   F   CH2 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                       ____________                                                ___EF___            
                                           85.2                                                    96.1                
                                       85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                        T   Y   R   V   V   S   V   L   P   I   Q   H   Q   D   W           L   N   G 
  AB699687 IGHG6-1*01   F   CH2 gDNA   acc tac cgt gtg gtc agc gtc cta cca atc cag cac cag gac tgg ... ... ctg aac ggg
                                                                                                                      
  M81771   IGHG6-1*02   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                           _________________________FG_________________________        
                                       
                                       100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                        K   E   F   K   C   K   V   N   N   K   D           L   P   A   P   I   T   R 
  AB699687 IGHG6-1*01   F   CH2 gDNA   aag gag ttc aag tgc aag gtc aac aac aaa gac ... ... ctc cca gcc ccc atc aca agg
                                                                                                                      
  M81771   IGHG6-1*02   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                                               
                                       
                                       120 121 122 123 124 125 
                                        I   I   S   K   A   K  
  AB699687 IGHG6-1*01   F   CH2 gDNA   atc atc tcc aag gcc aaa 
                                                               
  M81771   IGHG6-1*02   F   CH2 cDNA   --- --- --- --- --- --- 


                                                                                                                          
                                           
                                           1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                            G   Q   T   R   E   P   Q   V   Y   T   L   P   P   P   T   E 
  AB699687 IGHG6-1*01   F   CH3-CHS gDNA                   ggg cag acc cgg gag ccg cag gtg tac acc ctg ccc cca ccc acc gag
                                                                                                                          
  M81771   IGHG6-1*02   F   CH3-CHS cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                       _____AB_____                                            ____________
                                                       15.1    15.3                                                        
                                            13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                            E   L   S               R   S   K   L   S   V   T   C   L   I   T   G   F   Y 
  AB699687 IGHG6-1*01   F   CH3-CHS gDNA   gag ctg tcc ... ... ... agg agc aaa ctc agt gta acc tgc ctg atc act ggc ttc tac
                                                                                                                          
  M81771   IGHG6-1*02   F   CH3-CHS cDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                           _______BC___________________                            _____________CD_________
                                                                                                   45.1    45.3    45.5    
                                            30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                            P           P   D   I   D   V   E   W   Q   R   N   G   Q   P   E   P   E   G 
  AB699687 IGHG6-1*01   F   CH3-CHS gDNA   cca ... ... cct gac atc gat gtc gag tgg caa aga aac gga cag ccg gag cca gag ggc
                                                                                                                          
  M81771   IGHG6-1*02   F   CH3-CHS cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                           ____                                ___________________________DE_______________
                                           45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                                77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                N   Y   R   T   T   P   P   Q   Q   D   V   D                           G 
  AB699687 IGHG6-1*01   F   CH3-CHS gDNA   ... aat tac cgc acc acc ccg ccc cag cag gac gtg gac ... ... ... ... ... ... ggg
                                                                                                                          
  M81771   IGHG6-1*02   F   CH3-CHS cDNA   ... --- --- --- --- --- --- --- --- --- --t --- --- ... ... ... ... ... ... ---


                                           ____________                                                ___EF___            
                                               85.2                                                    96.1                
                                           85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                            T   Y   F   L   Y   S   K   L   A   V   D   K   A   S   W           Q   R   G 
  AB699687 IGHG6-1*01   F   CH3-CHS gDNA   acc tac ttc ctg tac agc aag ctc gcg gtg gac aag gcc agc tgg ... ... cag cgt gga
                                                                                                                          
  M81771   IGHG6-1*02   F   CH3-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                               _________________________FG_________________________        
                                           
                                           100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                            D   P   F   Q   C   A   V   M   H   E   A       L   H   N   H   Y   T   Q   K 
  AB699687 IGHG6-1*01   F   CH3-CHS gDNA   gac cca ttc cag tgt gcg gtg atg cac gag gct ... ctg cac aac cac tac acc cag aag
                                                                                                                          
  M81771   IGHG6-1*02   F   CH3-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- ---


                                                                               __CHS___
                                           
                                           120 121 122 123 124 125 126 127 128 129 130 
                                            S   I   F   K   T   P               G   N  
  AB699687 IGHG6-1*01   F   CH3-CHS gDNA   tcc atc ttc aag act ccg ... ... ... ggt aat 
                                                                                       
  M81771   IGHG6-1*02   F   CH3-CHS cDNA   --- --- --- --- --- --- ... ... ... --- --- 


                                     
                                      
                                       1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                       E   L   L   L   E   E   S   C   A   D   A   Q   D   G   E   L   D   G   L   W 
  AB699687 IGHG6-1*01   F   M1 gDNA   gaa ctg ctc ctg gag gag agc tgt gcc gac gcc cag gac ggg gag ctg gac ggg ctc tgg


                                      
                                      
                                       21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                       T   T   I   S   I   F   I   T   L   F   L   L   S   V   C   Y   S   A   T   V 
  AB699687 IGHG6-1*01   F   M1 gDNA   acc acc atc tcc atc ttc atc acg ctc ttc ctg ctc agc gtg tgc tac agc gcc acc gtg


                                      
                                      
                                       41  42  43  44 
                                       T   L   F   K  
  AB699687 IGHG6-1*01   F   M1 gDNA   acg ctc ttc aag 


                                     
                                      
                                       1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                       V   K   W   I   F   S   S   V   V   E   L   K   R   T   I   V   P   D   Y   R 
  AB699687 IGHG6-1*01   F   M2 gDNA   gtg aag tgg atc ttc tcg tcg gtg gtg gag ctg aag cgg acc att gtc ccc gac tac aga


                                      
                                      
                                       21  22  23  24  25  26  27 
                                       N   M   I   G   Q   G   A  
  AB699687 IGHG6-1*01   F   M2 gDNA   aac atg atc ggg cag ggg gcc 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
17/09/2014
Last updated:
27/05/2016
Authors:
Saida Saljoqi