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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                 
                                            
                                             1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                             E   E   K   L   V   E   S   G   G       G   L   V   Q   P   G   G   S   L   R 
  AB513624 IGHV1-6*01   F   V-REGION gDNA   gag gag aag ctg gtg gag tct gga gga ... ggc ctg gtg cag cct ggg ggg tct ctg aga
                                                                                                                           
  AF064687 IGHV1-6*02   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---


                                                                    ___________________CDR1-IMGT____________________        
                                            
                                             21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                             L   S   C   V   G   S   G   F   D   F                   S   D   N   A   F   S 
  AB513624 IGHV1-6*01   F   V-REGION gDNA   ctc tcc tgt gtc ggc tct gga ttc gac ttc ... ... ... ... agt gac aac gct ttc agc
                                                                                                                           
  AF064687 IGHV1-6*02   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---


                                                                                                        _______________CDR2-
                                            
                                             41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                             W   V   R   Q   A   P   G   K   G   L   E   W   V   A   A   I   A   S   S   D 
  AB513624 IGHV1-6*01   F   V-REGION gDNA   tgg gtc cgc cag gct cca ggg aag ggg ctg gag tgg gtc gca gcc att gct agt agt gac
                                                                                                                           
  AF064687 IGHV1-6*02   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                            IMGT________________                                                            
                                            
                                             61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80 
                                             Y   D   G   S   T   Y   Y   A   D   S   V   K       G   R   F   T   I   S   S 
  AB513624 IGHV1-6*01   F   V-REGION gDNA   tat gac ggt agc acc tac tac gca gac tct gtg aag ... ggc cga ttc acc atc tcc agc
                                                                                                                         R 
  AF064687 IGHV1-6*02   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --a


                                                                                                                            
                                            
                                             81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100 
                                             D   N   S   Q   N   T   V   Y   L   Q   M   N   S   L   R   T   E   D   T   A 
  AB513624 IGHV1-6*01   F   V-REGION gDNA   gac aac tcc cag aac acg gtg tat ctg caa atg aac agc ctc aga acc gaa gac acg gcc
                                                                                                                           
  AF064687 IGHV1-6*02   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                            _CDR3-IMGT__
                                            
                                            101 102 103 104 105 106 
                                             R   Y   Y   C   A   I  
  AB513624 IGHV1-6*01   F   V-REGION gDNA   cgg tat tac tgt gcg ata gg
                                                                    
  AF064687 IGHV1-6*02   F   V-REGION gDNA   --- --- --- --- --- --- --

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
17/11/2014
Last updated:
27/05/2016
Authors:
Joumana jabado-Michaloud