Alleles are described at the species level.When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated
in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest
sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
Cysteine involved in the disulfide bridge are shown in purple.
STOP-CODON is indicated by an asterisk.
Alleles are described at the species level.
1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
(R) A D A A P T V S I F P P S S
V00807 ,IGKC*01 (C)GG GCT GAT GCT GCA CCA ACT GTA TCC ATC TTC CCA CCA TCC AGT
V00777 ,IGKC*01 (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
V01569 ,IGKC*01 (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67003 ,IGKC*01 (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67004 ,IGKC*01(2) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67005 ,IGKC*01(2) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67006 ,IGKC*01(3) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67007 ,IGKC*01(4) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67010 ,IGKC*01(7) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67012 ,IGKC*01(2) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
V00806 ,IGKC*01 (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67002 ,IGKC*02(1) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67008 ,IGKC*02(5) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67009 ,IGKC*02(6) (-)-- --- --- X-- --- --- --- --- --- --- --- --- --- --- ---
X67011 ,IGKC*03(8) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
E Q L T S G G A S V V C F L N N F
V00807 ,IGKC*01 GAG CAG TTA ACA ... ... ... TCT GGA GGT GCC TCA GTC GTG TGC TTC TTG AAC AAC TTC
V00777 ,IGKC*01 --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
V01569 ,IGKC*01 --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X67003 ,IGKC*01 --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X67004 ,IGKC*01(2) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X67005 ,IGKC*01(2) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X67006 ,IGKC*01(3) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X67007 ,IGKC*01(4) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X67010 ,IGKC*01(7) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X67012 ,IGKC*01(2) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X67002 ,IGKC*02(1) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X67008 ,IGKC*02(5) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X67009 ,IGKC*02(6) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X67011 ,IGKC*03(8) --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
Y P K D I N V K W K I D G S E R Q N
V00807 ,IGKC*01 TAC CCC ... ... AAA GAC ATC AAT GTC AAG TGG AAG ATT GAT GGC AGT GAA CGA CAA AAT
V00777 ,IGKC*01 --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
V01569 ,IGKC*01 --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67003 ,IGKC*01 --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67004 ,IGKC*01(2) --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67005 ,IGKC*01(2) --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67006 ,IGKC*01(3) --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67007 ,IGKC*01(4) --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67010 ,IGKC*01(7) --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67012 ,IGKC*01(2) --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67002 ,IGKC*02(1) --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67008 ,IGKC*02(5) --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67009 ,IGKC*02(6) --- --- ... ... --- -X- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
R
X67011 ,IGKC*03(8) --- --- ... ... -G- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G V L N S W T D Q D S K D
V00807 ,IGKC*01 ... ... GGC GTC CTG AAC AGT TGG ACT GAT CAG GAC AGC AAA GAC ... ... ... ... ...
V00777 ,IGKC*01 ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
V01569 ,IGKC*01 ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67003 ,IGKC*01 ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67004 ,IGKC*01(2) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67005 ,IGKC*01(2) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67006 ,IGKC*01(3) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67007 ,IGKC*01(4) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67010 ,IGKC*01(7) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67012 ,IGKC*01(2) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67002 ,IGKC*02(1) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67008 ,IGKC*02(5) ... ... --- --- --- XXX --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67009 ,IGKC*02(6) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67011 ,IGKC*03(8) ... ... --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
S T Y S M S S T L T L T K D E Y E R
V00807 ,IGKC*01 AGC ACC TAC AGC ATG AGC AGC ACC CTC ACG TTG ACC AAG GAC GAG TAT ... ... GAA CGA
V00777 ,IGKC*01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
V01569 ,IGKC*01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67003 ,IGKC*01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67004 ,IGKC*01(2) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67005 ,IGKC*01(2) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67006 ,IGKC*01(3) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67007 ,IGKC*01(4) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67010 ,IGKC*01(7) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67012 ,IGKC*01(2) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67002 ,IGKC*02(1) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67008 ,IGKC*02(5) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67009 ,IGKC*02(6) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67011 ,IGKC*03(8) --- --- --- --- --- --- --- --- --- --A --- --- --- --- --- --- --- --- --- ---
_______________________FG___________________________
99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
H N S Y T C E A T H K T S T S P I V
V00807 ,IGKC*01 CAT AAC AGC TAT ACC TGT GAG GCC ACT CAC AAG ACA ... ... TCA ACT TCA CCC ATT GTC
V00777 ,IGKC*01 --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- ---
V01569 ,IGKC*01 --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- ---
X67003 ,IGKC*01 --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- ---
X67004 ,IGKC*01(2) --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- ---
X67005 ,IGKC*01(2) --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- ---
X67006 ,IGKC*01(3) --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- ---
X67007 ,IGKC*01(4) --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- ---
X67010 ,IGKC*01(7) --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- ---
X67012 ,IGKC*01(2) --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- ---
X67002 ,IGKC*02(1) --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --C ---
X67008 ,IGKC*02(5) --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --C ---
X67009 ,IGKC*02(6) --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --C ---
X67011 ,IGKC*03(8) --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --C ---
119 120 121 122 123 124 125 126
K S F N R N E C *
V00807 ,IGKC*01 AAG AGC TTC AAC AGG AAT GAG TGT
V00777 ,IGKC*01 --- --- --- --- --- --- --- ---
V01569 ,IGKC*01 --- --- --- --- --- --- --- ---
X67003 ,IGKC*01 --- --- --- --- --- --- --- ---
X67004 ,IGKC*01(2) --- --- --- --- --- --- --- ---
X67005 ,IGKC*01(2) --- --- --- --- --- --- --- ---
X67006 ,IGKC*01(3) --- --- --- --- --- --- --- ---
X67007 ,IGKC*01(4) --- --- --- --- --- --- --- ---
X67010 ,IGKC*01(7) --- --- --- --- --- --- --- ---
X67012 ,IGKC*01(2) --- --- --- --- --- --- --- ---
X67002 ,IGKC*02(1) --- --- --- --- --- --- --- ---
X67008 ,IGKC*02(5) --- --- --- --- --- --- --- -X-
X67009 ,IGKC*02(6) --- --- --- --- --- --- --- ---
X67011 ,IGKC*03(8) --- --- --- --- --- --- --- ---
Mouse (Mus saxicola) IGKC
Mouse (Mus pahari) IGKC
Mouse (Mus minutoides) IGKC
1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
G A D V A P T A S I F P P S S
M21792 ,IGKC*01 (G)GG GCT GAT GTT GCA CCA ACT GCA TCC ATC TTC CCA CCA TCC AGT
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
E Q L A S G G A S V V C F M N N F
M21792 ,IGKC*01 GAG CAG TTA GCA ... ... ... TCT GGA GGT GCC TCA GTC GTG TGC TTC ATG AAC AAC TTC
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
Y P K D I S V K W K V D G S E R Q D
M21792 ,IGKC*01 TAC CCC ... ... AAA GAC ATC AGT GTC AAG TGG AAG GTT GAT GGC AGT GAA CGA CAA GAT
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G F L N S W T E Q D S K D
M21792 ,IGKC*01 ... ... GGC TTC CTG AAC AGT TGG ACT GAA CAG GAC AGC AAA GAC ... ... ... ... ...
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
S T Y S M S S T L T L T K D E Y E R
M21792 ,IGKC*01 AGC ACC TAC AGC ATG AGC AGC ACC CTC ACA TTG ACC AAG GAT GAG TAT ... ... GAA CGA
_______________________FG___________________________
99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
H N S Y T C E A T H K T S S S P I V
M21792 ,IGKC*01 CAT AAC AGC TAT ACC TGT GAG GCC ACT CAT AAG ACG ... ... TCA TCT TCA CCC ATC GTC
119 120 121 122 123 124 125 126
K S F N R N E C *
M21792 ,IGKC*01 AAG AGC TTC AAC AGG AAT GAG TGT
1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
G A D V A P T A S I F P P S N
M21793 ,IGKC*01 (G)GG GCT GAT GTT GCA CCA ACT GCA TCC ATC TTC CCA CCA TCC AAT
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
E Q L A S G G A S I V C F L N N F
M21793 ,IGKC*01 GAG CAG TTA GCA ... ... ... TCT GGA GGT GCC TCA ATC GTG TGT TTC CTG AAC AAC TTC
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
Y P R D I N V K W K V D G S E K Q D
M21793 ,IGKC*01 TAC CCC ... ... AGA GAC ATC AAT GTC AAG TGG AAG GTT GAT GGC AGT GAA AAA CAA GAT
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G V L N S W T E Q D S K D
M21793 ,IGKC*01 ... ... GGC GTC CTG AAC AGT TGG ACT GAA CAG GAC AGC AAG GAC ... ... ... ... ...
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
S T Y S M S S T L T L T K A E Y E Q
M21793 ,IGKC*01 AGC ACC TAC AGC ATG AGC AGC ACC CTC ACA TTG ACC AAG GCA GAG TAT ... ... GAA CAA
_______________________FG___________________________
99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
H N S Y T C E A V H K T S S S P I V
M21793 ,IGKC*01 CAT AAC AGC TAT ACC TGT GAG GCC GTT CAT AAA ACA ... ... TCA AGT TCA CCC ATC GTC
119 120 121 122 123 124 125 126
K S F N R N E C *
M21793 ,IGKC*01 AAG AGC TTC AAC AGG AAT GAG TGT
1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
G S D V A P T A S I F P P S S
M21794 ,IGKC*01 (G)GG TCT GAT GTT GCA CCA ACT GCA TCC ATC TTC CCG CCA TCC AGT
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
E Q L A S G G A S V V C F M N N F
M21794 ,IGKC*01 GAG CAG TTA GCA ... ... ... TCT GGA GGT GCC TCA GTC GTG TGC TTC ATG AAC AAC TTC
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
Y P R D I N V K W K I D G N E R R D
M21794 ,IGKC*01 TAC CCC ... ... AGA GAC ATC AAT GTC AAG TGG AAG ATT GAT GGC AAT GAA CGT CGA GAT
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G I L T S Y T D Q D S K D
M21794 ,IGKC*01 ... ... GGC ATC CTG ACC AGT TAT ACT GAT CAG GAC AGC AAA GAC ... ... ... ... ...
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
S T Y S L S S T L T L T K D E Y E R
M21794 ,IGKC*01 AGC ACC TAC AGC TTG AGC AGC ACC CTC ACA TTG ACC AAG GAC GAG TAT ... ... GAA CGA
_______________________FG___________________________
99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
H N S Y T C E A T H K T S T S P I V
M21794 ,IGKC*01 CAT AAC AGC TAT ACC TGT GAG GCC ACT CAC AAG ACG ... ... TCA ACT TCG CCC ATC GTC
119 120 121 122 123 124 125 126
K S F N R N E C *
M21794 ,IGKC*01 AAG AGC TTC AAC AGG AAT GAG TGT
This alignment has been generated with the IMGT/AlleleAlign tool developed by Mehdi Yousfi (31/07/2001).
Created: Monday, 11-Jul-2011 12:56:58 CEST
Author: Delphine Guiraudou
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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Marie-Paule.Lefranc@igh.cnrs.fr
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