First codon and amino acid at position 1.3 depends on the last nucleotide of the TRA J-REGION
(Alignment of alleles: Mouse (Mus musculus) TRAJ).
This amino acid may be an N (aac), H (cac), D (gac) or Y (tac).
When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated
in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest
sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt).
Exon names are shown between parentheses on the first line.
The Cysteines involved in the TR EX1 intrachain disulfide bridge are shown with a larger letter C in purple.
Other Cysteines (including those involved in the interchain disulfide bridge) are shown with a larger letter C in black.
STOP-CODON is indicated by an asterisk.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CH-S and in pages edited before 14/10/2009).
First codon and amino acid at position 1.3 depends on the last nucleotide of the TRA J-REGION
(Alignment of alleles: Mouse (Mus musculus) TRAJ).
This amino acid may be an N (aac), H (cac), D (gac) or Y (tac).
1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
D I Q N P E P A V Y Q L K D
M64239 ,TRAC*01 (EX1) (G)AC ATC CAG AAC CCA GAA CCT GCT GTG TAC CAG TTA AAA GAT
M14506 ,TRAC*01 (cDNA) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67127 ,TRAC*02 (cDNA) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- ---
X01134 ,TRAC*02 (cDNA) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- ---
M16118 ,TRAC*02 (cDNA) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- ---
M16119 ,TRAC*02 (cDNA) (-)-- --- --- --- --- --- --- --- --- --- --- --- --- ---
___AB_______ _______
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
P R S Q D S T L C L F T D F
M64239 ,TRAC*01 (EX1) CCT CGG ... ... ... ... ... ... TCT CAG GAC AGC ACC CTC TGC CTG TTC ACC GAC TTT
M14506 ,TRAC*01 (cDNA) --- --- ... ... ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- ---
X67127 ,TRAC*02 (cDNA) --- --- ... ... ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- ---
X01134 ,TRAC*02 (cDNA) --- --- ... ... ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- ---
M16118 ,TRAC*02 (cDNA) --- --- ... ... ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- ---
M16119 ,TRAC*02 (cDNA) --- --- ... ... ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- ---
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
D S Q I N V P K T M E S
M64239 ,TRAC*01 (EX1) GAC TCC ... ... ... CAA ATC AAT GTG CCG AAA ACC ATG GAA TCT ... ... ... ... ...
M14506 ,TRAC*01 (cDNA) --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...
X67127 ,TRAC*02 (cDNA) --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...
X01134 ,TRAC*02 (cDNA) --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...
M16118 ,TRAC*02 (cDNA) --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...
M16119 ,TRAC*02 (cDNA) --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G T F I T D K T V L D M K A M D
M64239 ,TRAC*01 (EX1) ... ... GGA ACG TTC ATC ACT GAC AAA ACT GTG CTG GAC ATG AAA GCT ... ... ATG GAT
M14506 ,TRAC*01 (cDNA) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- ---
X67127 ,TRAC*02 (cDNA) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- ---
X01134 ,TRAC*02 (cDNA) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- ---
M16118 ,TRAC*02 (cDNA) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- ---
M16119 ,TRAC*02 (cDNA) ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- ---
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
S K S N G A I A W S N Q T
M64239 ,TRAC*01 (EX1) TCC AAG AGC AAT GGG GCC ATT GCC TGG AGC AAC CAG ACA ... ... ... ... ... ... ...
M14506 ,TRAC*01 (cDNA) --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ...
X67127 ,TRAC*02 (cDNA) --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ...
X01134 ,TRAC*02 (cDNA) --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ...
M16118 ,TRAC*02 (cDNA) --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ...
M16119 ,TRAC*02 (cDNA) --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ...
_______________________FG___________________________
99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
S F T C Q D I F K E T N A T Y P S
M64239 ,TRAC*01 (EX1) ... ... AGC TTC ACC TGC CAA GAT ATC TTC AAA GAG ... ACC AAC GCC ACC TAC CCC AGT
M14506 ,TRAC*01 (cDNA) ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
X67127 ,TRAC*02 (cDNA) ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
X01134 ,TRAC*02 (cDNA) ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
M16118 ,TRAC*02 (cDNA) ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
M16119 ,TRAC*02 (cDNA) ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
119
S
M64239 ,TRAC*01 (EX1) TCA G
M14506 ,TRAC*01 (cDNA) --- -
X67127 ,TRAC*02 (cDNA) --- -
X01134 ,TRAC*02 (cDNA) --- -
M16118 ,TRAC*02 (cDNA) --- -
M16119 ,TRAC*02 (cDNA) --- -
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
D V P C D A T L T E K S F E T
M64239 ,TRAC*01 (EX2) AC GTT CCC TGT GAT GCC ACG TTG ACT GAG AAA AGC TTT GAA ACA G
M14506 ,TRAC*01 (cDNA) -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -
X67127 ,TRAC*02 (cDNA) -- --- --- --- --- --- --- --- --C --- --- --- --- --- --- -
X01134 ,TRAC*02 (cDNA) -- --- --- --- --- --- --- --- --C --- --- --- --- --- --- -
M16118 ,TRAC*02 (cDNA) -- --- --- --- --- --- --- --- --C --- --- --- --- --- --- -
M16119 ,TRAC*02 (cDNA) -- --- --- --- --- --- --- --- --C --- --- --- --- --- --- -
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
D M N L N F Q N L S V M G L R I L L L K
M64239 ,TRAC*01 (EX3) AT ATG AAC CTA AAC TTT CAA AAC CTG TCA GTT ATG GGA CTC CGA ATC CTC CTG CTG AAA
M14506 ,TRAC*01 (cDNA) -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X67127 ,TRAC*02 (cDNA) -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X01134 ,TRAC*02 (cDNA) -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
M16118 ,TRAC*02 (cDNA) -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
M16119 ,TRAC*02 (cDNA) -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
V A G F N L L M T L R L W S S *
M64239 ,TRAC*01 (EX3) GTA GCC GGA TTT AAC CTG CTC ATG ACG CTG AGG CTG TGG TCC AGT TGA G
M14506 ,TRAC*01 (cDNA) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -
X67127 ,TRAC*02 (cDNA) --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- -
X01134 ,TRAC*02 (cDNA) --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- -
M16118 ,TRAC*02 (cDNA) --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- -
M16119 ,TRAC*02 (cDNA) --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- -
M64239 ,TRAC*01 (Untranslated EX4 GTCTGCAAGACTGACAGAGCCTGACTCCCAAGCTCCATCCTCCTCACCCCTCCGCTCCTTCTTCAAGCCAAAAGGAGCCC
and 3'UTR)
M14506 ,TRAC*01 (cDNA) --------------------------------------------------------------------------------
#
X67127 ,TRAC*02 (cDNA) --------------------------------T---G---------------------C-------------------..
#
X01134 ,TRAC*02 (cDNA) --------------------------------T---G---------------------C-------------------..
#
M16118 ,TRAC*02 (cDNA) --------------------------------T---G---------------------C-------------------..
#
M16119 ,TRAC*02 (cDNA) --------------------------------T---G---------------------C-------------------..
M64239 ,TRAC*01 TCCCACCTCGTCAAGACGGCTGTCTGGGGTCTGGTTGGCCCTGATTCACAATCCCACCTGGATCTCCCAGATTTGTGAGG 160
M14506 ,TRAC*01 (cDNA) --------------------------------------------------------------------------------
#
X67127 ,TRAC*02 (cDNA) ................----------------------------------------------------------------
#
X01134 ,TRAC*02 (cDNA) ................----------------------------------------------------------------
# #
M16118 ,TRAC*02 (cDNA) ................------------------------.---------------------------------------
#
M16119 ,TRAC*02 (cDNA) ................----------------------------------------------------------------
M64239 ,TRAC*01 AAGGTTGCTGGAGAGCTAAGCACTGCTGCCGCACCCACTCAGCTCCCTCACTGCTGCTGACCATTCACAAAAAA------
M14506 ,TRAC*01 (cDNA) ----------
# #
X67127 ,TRAC*02 (cDNA) ---------A-----------G----------------------------------------------------AAAAAA
# #
X01134 ,TRAC*02 (cDNA) ---------A-----------G----------------------------------------------------AAAAA-
# #
M16118 ,TRAC*02 (cDNA) ---------A-----------G----------------------------------------------------AAAAA-
# #
M16119 ,TRAC*02 (cDNA) ---------A-----------G----------------------------------------------------AAAAA-
M64239 ,TRAC*01 CGGCAGGGGCGGGGCTTCTCCTGGATCTGAAGACCCCTCCCCCATGGCAGACTCCCCTGTAAAATCTCTTGGAGAATGTT 320
X67127 ,TRAC*02 (cDNA) ----------------------------------------------------------A---------------------
X01134 ,TRAC*02 (cDNA) ----------------------------------------------------------A---------------------
M16118 ,TRAC*02 (cDNA) ----------------------------------------------------------A---------------------
M16119 ,TRAC*02 (cDNA) ----------------------------------------------------------A---------------------
M64239 ,TRAC*01 GTAAAAAAAATATCGGTTGTTTTTTGTTTTTTTTTTTTTTGCGGGTTTATTTTTTTAAGCATCCATGAAGAAATGCATAT
# # #
X67127 ,TRAC*02 (cDNA) -------..----G----...........----------G---------C----------------A-------------
# # #
X01134 ,TRAC*02 (cDNA) -------..----G----...........----------G---------C----------------A-------------
# # #
M16118 ,TRAC*02 (cDNA) -------..----G----...........----------G---------C----------------A-------------
# # #
M16119 ,TRAC*02 (cDNA) -------..----G----...........----------G---------C----------------A-------------
M64239 ,TRAC*01 TACTCTTTCATCAAGGTGTAGAAATTATCTCATTGTCTAGACCCTCCTGCTACTGTGTGTATTGAGCCACATTGTATATT 480
X67127 ,TRAC*02 (cDNA) --------------------------------------------------------------------------------
X01134 ,TRAC*02 (cDNA) --------------------------------------------------------------------------------
M16118 ,TRAC*02 (cDNA) --------------------------------------------------------------------------------
#
M16119 ,TRAC*02 (cDNA) --------------------------.-----------------------------------------------------
M64239 ,TRAC*01 ATTCTGCTGTCCATGACATCATTAAAGGTGATTCAGAAA
X67127 ,TRAC*02 (cDNA) ---------C-----------------------------
X01134 ,TRAC*02 (cDNA) ---------C-----------------------------
M16118 ,TRAC*02 (cDNA) ---------C-----------------------------
M16119 ,TRAC*02 (cDNA) ---------C-----------------------------
#: Nucleotide deletion or insertion
A DONOR-SPLICE, located just after the termination codon, uses a dowstream ACCEPTOR-SPLICE, placing part
of the 3' non-coding sequence on a separate untranslated exon, designated as EX4.
Since EX4 is untranslated, nucleotide differences observed in EX4 are not taken into account for the description of alleles,
according to IMGT allele nomenclature and sequence polymorphisms.
Created: 09/05/2001
Last updated: Wednesday, 29-Jun-2011 17:06:02 CEST
Author: Nathalie Bosc
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
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