When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated
in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest
sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt).
Exon names are shown between parentheses on the first line.
The Cysteines involved in the TR EX1 intrachain disulfide bridge are shown with a larger letter C in purple.
Other Cysteines (including those involved in the interchain disulfide bridge) are shown with a larger letter C in black.
STOP-CODON is indicated by an asterisk.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CH-S and in pages edited before 14/10/2009).
1.7 1.6 1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
E D L R N V T P P K V S L F E P S K
M26057 ,TRBC2*01, (EX1) (G)AG GAT CTG AGA AAT GTG ACT CCA CCC AAG GTC TCC TTG TTT GAG CCA TCA AAA
K02803 ,TRBC2*01 (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X03574 ,TRBC2*02 (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
M35181 ,TRBC2*02 (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
AE000665,TRBC2*03 (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
A E I A N K Q K A T L V C L A R G F
M26057 ,TRBC2*01 GCA GAG ATT GCA AAC ... ... AAA CAA AAG GCT ACC CTC GTG TGC TTG GCC AGG GGC TTC
K02803 ,TRBC2*01 --- --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
X03574 ,TRBC2*02 --- --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
M35181 ,TRBC2*02 --- --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
AE000665,TRBC2*03 --- --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
F P D H V E L S W W V N G K E V H S
M26057 ,TRBC2*01 TTC CCT ... ... GAC CAC GTG GAG CTG AGC TGG TGG GTG AAT GGC AAG GAG GTC CAC AGT
K02803 ,TRBC2*01 --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
R
X03574 ,TRBC2*02 --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- -G- --- --- --- ---
R
M35181 ,TRBC2*02 --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- -G- --- --- --- ---
AE000665,TRBC2*03 --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G V S T D P Q A Y K E S N
M26057 ,TRBC2*01 ... ... GGG GTC AGC ACG GAC CCT CAG GCC TAC AAG GAG AGC AAT ... ... ... ... ...
K02803 ,TRBC2*01 ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...
X03574 ,TRBC2*02 ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...
M35181 ,TRBC2*02 ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...
AE000665,TRBC2*03 ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
Y S Y C L S S R L R V S A T F W H N P
M26057 ,TRBC2*01 TAT AGC TAC TGC CTG AGC AGC CGC CTG AGG GTC TCT GCT ACC TTC TGG CAC ... AAT CCT
K02803 ,TRBC2*01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... --- ---
X03574 ,TRBC2*02 --- --- --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- ... --- ---
M35181 ,TRBC2*02 --- --- --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- ... --- ---
AE000665,TRBC2*03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... --- ---
_________________________________________________FG____
111.1 111.3 111.5 112.6
99 100 101 102 103 104 105 106 107 108 109 110 111 111.2 111.4 111.6
R N H F R C Q V Q F H G L S E E D K W P
M26057 ,TRBC2*01 CGA AAC CAC TTC CGC TGC CAA GTG CAG TTC CAT GGG CTT TCA GAG GAG GAC AAG TGG CCA
K02803 ,TRBC2*01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X03574 ,TRBC2*02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
M35181 ,TRBC2*02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
AE000665,TRBC2*03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
_____________________________________________
112.4 112.2
112.5 112.3 112.1 112 113 114 115 116 117 118 119 120 121 122 123 124 125
E G S P K P V T Q N I S A E A W G R A
M26057 ,TRBC2*01 GAG GGC TCA CCC AAA CCT GTC ACA CAG AAC ATC AGT GCA GAG GCC TGG GGC CGA GCA G
K02803 ,TRBC2*01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -
X03574 ,TRBC2*02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -
M35181 ,TRBC2*02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -
AE000665,TRBC2*03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -
1 2 3 4 5 6
D C G I T S
M26058 ,TRBC2*01, (EX2) AC TGT GGA ATC ACT TCA G
AE000665,TRBC2*03 -- --- --- --- --- --- -
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
A S Y H Q G V L S A T I L Y E I L L G K
M26059 ,TRBC2*01, (EX3) CA TCC TAT CAT CAG GGG GTT CTG TCT GCA ACC ATC CTC TAT GAG ATC CTA CTG GGG AAG
AE000665,TRBC2*03 -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
A T L Y A V L V S G L V L M A M
M26059 ,TRBC2*01 GCC ACC CTA TAT GCT GTG CTG GTC AGT GGC CTA GTG CTG ATG GCC ATG
AE000665,TRBC2*03 --- --- --- --- --- --- --- --- --- --- --G --- --- --- --- ---
1 2 3 4 5 6
V K K K N S *
M26060 ,TRBC2*01, (EX4) GTC AAG AAA AAA AAT TCC
AE000665,TRBC2*03 --- --- --- --- --- ---
1.7 1.6 1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
E D L R N V T P P K V S L F E P S R
M28760 ,TRBC2*01, (EX1) (G)AG GAT CTG AGA AAT GTG ACT CCA CCC AAG GTC TCC TTG TTT GAG CCA TCA AGA
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
A E I A N K Q K A T L V C L A R G F
M28760 ,TRBC2*01 GCA GAG ATT GCA AAC ... ... AAA CAA AAG GCT ACC CTC GTG TGC TTG GCC AGG GGC TTC
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
F P D H V E L S W W V N G K E V H S
M28760 ,TRBC2*01 TTC CCT ... ... GAC CAC GTG GAG CTG AGC TGG TGG GTG AAT GGC AAG GAG GTC CAC AGT
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G V S T D P Q A Y K E S N
M28760 ,TRBC2*01 ... ... GGG GTC AGC ACG GAC CCT CAG GCC TAC AAG GAG AGC AAT ... ... ... ... ...
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
Y S Y C L S S R L R V S A T F W H N P
M28760 ,TRBC2*01 TAT AGC TAC TGC CTG AGC AGC CGC CTG AGG GTC TCT GCT ACC TTC TGG CAC ... AAT CCT
__________________________________________________FG__
111.1 111.3 111.5 112.6
99 100 101 102 103 104 105 106 107 108 109 110 111 111.2 111.4 111.6
R N H F R C Q V Q F H G L S E E D R W P
M28760 ,TRBC2*01 CGC AAC CAC TTC CGC TGC CAA GTG CAG TTC CAT GGG CTT TCA GAG GAG GAC AGG TGG CCA
_____________________________________________
112.4 112.2
112.5 112.3 112.1 112 113 114 115 116 117 118 119 120 121 122 123 124 125
E G S P K P V T Q N I S A E A W G R A
M28760 ,TRBC2*01 GAG GGC TCA CCC AAA CCT GTC ACA CAG AAC ATC AGT GCA GAG GCC TGG GGC CGA GCA G
1 2 3 4 5 6
D C G I T S
M28762 ,TRBC2*01, (EX2) AC TGT GGA ATC ACT TCA G
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
A S Y H Q G V L S A T I L Y E I L L G K
M28764 ,TRBC2*01, (EX3) CA TCC TAT CAT CAG GGG GTT CTG TCT GCA ACC ATC CTC TAT GAG ATC CTA CTG GGG AAG
21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
A T L Y A V L V S V L V L M A M
M28764 ,TRBC2*01 GCC ACC CTA TAT GCT GTG CTG GTC AGT GTC CTG GTG CTG ATG GCC ATG
1 2 3 4 5 6
V K K K N S *
M28766 ,TRBC2*01, (EX4) GTC AAG AAA AAA AAT TCC
1.7 1.6 1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
E N L R N V T P P K V S L F E P S A
S92301 ,TRBC2*01, (EX1) (G)AG AAT CTG AGA AAT GTG ACT CCA CCC AAG GTC TCC TTG TTT GAG CCA TCA GCA
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
A E I A D K Q K A T L V C L A R G F
S92301 ,TRBC2*01 GCA GAG ATC GCA GAC ... ... AAA CAA AAG GCT ACC CTC GTG TGC TTG GCC AGG GGC TTC
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
F P D H V E L S W W V N G K Q V H S
S92301 ,TRBC2*01 TTC CCT ... ... GAC CAC GTG GAG CTG AGC TGG TGG GTC AAT GGC AAG CAG GTC CAC AGT
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G V S T D P Q A Y K E S N N
S92301 ,TRBC2*01 ... ... GGG GTC AGC ACG GAC CCT CAG GCC TAC AAG GAG AGC AAT ... ... ... ... AAC
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
S S Y C L S S R L R V S A T F W H N P
S92301 ,TRBC2*01 AGC AGC TAC TGC CTG AGC AGC CGC CTG AGG GTG TCT GCT ACC TTC TGG CAC ... AAT CCT
__________________________________________________FG___
111.1 111.3 111.5 112.6
99 100 101 102 103 104 105 106 107 108 109 110 111 111.2 111.4 111.6
R N H F R C Q V Q F Y G L S E E D K W P
S92301 ,TRBC2*01 CGC AAT CAC TTC CGC TGC CAA GTG CAG TTC TAT GGG CTT TCA GAG GAA GAC AAG TGG CCA
_____________________________________________
112.4 112.2
112.5 112.3 112.1 112 113 114 115 116 117 118 119 120 121 122 123 124 125
E D S P K P V T Q N I S V E A W G R E
S92301 ,TRBC2*01 GAG GAC TCA CCC AAA CCT GTC ACA CAG AAC ATC AGT GTA GAG GCC TGG GGC CGA GAA G
1 2 3 4 5 6
G C G I T S
S92301 ,TRBC2*01, (EX2) GC TGT GGA ATC ACC TCC A
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
E S Y H Q G V L S A T I L Y E I L L G K
S92301 ,TRBC2*01, (EX3) AA TCC TAT CAT CAA GGG GTT CTA TCT GCC ACC ATC CTC TAT GAG ATC CTA CTG GGG AAG
21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
A T L Y A V L V S A L V L M A M
S92301 ,TRBC2*01 GCC ACC CTA TAT GCT GTG CTG GTC AGT GCC CTG GTG CTG ATG GCC ATG
1 2 3 4 5 6
V K K K N S *
S92301 ,TRBC2*01, (EX4) GTC AAG AAA AAA AAC TCC
1.7 1.6 1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
Q D L R N V T P P K V S L F E P S E
M28601 ,TRBC2*01, (EX1) (C)AG GAT CTG AGA AAT GTG ACT CCA CCC AAG GTC TCC TTG TTT GAG CCA TCA GAA
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
A E I A D K Q K A T L V C L A R G F
M28601 ,TRBC2*01 GCA GAG ATT GCT GAC ... ... AAA CAA AAG GCT ACC CTC GTG TGC TTG GCC AGG GGC TTC
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
F P D H V E L S W W V N G K E V H S
M28601 ,TRBC2*01 TTC CCT ... ... GAC CAC GTG GAG CTG AGC TGG TGG GTG AAT GGC AAG GAG GTC CAC AGT
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G V S T D P Q A Y K E S N
M28601 ,TRBC2*01 ... ... GGG GTC AGC ACA GAC CCT CAG GCC TAC AAG GAG AGC AAT ... ... ... ... ...
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
N S Y C L S S R L R V S A T Y W H N P
M28601 ,TRBC2*01 AAC AGC TAC TGC CTG AGC AGC CGC CTG AGG GTT TCT GCG ACC TAC TGG CAC ... AAT CCT
__________________________________________________FG___
111.1 111.3 111.5 112.6
99 100 101 102 103 104 105 106 107 108 109 110 111 111.2 111.4 111.6
R N H F R C Q V Q F Y G L E E E D K W P
M28601 ,TRBC2*01 CGC AAC CAC TTC CGC TGC CAA GTG CAG TTC TAT GGG CTT GAA GAG GAG GAC AAG TGG CCA
_____________________________________________
112.4 112.2
112.5 112.3 112.1 112 113 114 115 116 117 118 119 120 121 122 123 124 125
E G S T K P V T Q N I S A E A W G R A
M28601 ,TRBC2*01 GAG GGC TCA ACC AAA CCT GTC ACA CAG AAC ATC AGT GCA GAG GCC TGG GGC CGA GCA G
1 2 3 4 5 6
D S G I T S
M28601 ,TRBC2*01, (EX2) AC TCT GGA ATC ACC TCA G
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
V S Y R Q G V L S A T V L Y E I R L G K
M28601 ,TRBC2*01, (EX3) TA TCC TAT CGT CAG GGG GTT CTG TCT GCC ACC GTC CTC TAT GAG ATC CGA CTG GGG AAG
21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
A T L Y A A L V S A L V L M A M
M28601 ,TRBC2*01 GCC ACC CTG TAT GCT GCG CTG GTC AGC GCC CTG GTA CTG ATG GCC ATG
1 2 3 4 5 6
V K K K N S *
M28601 ,TRBC2*01, (EX4) GTC AAG AAA AAA AAT TCC
Created: 26/10/1999
Last updated: Tuesday, 03-Apr-2012 08:20:22 CEST
Author: Nathalie Bosc
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
|
IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr |
|
|
|
|
Citing IMGT © Copyright 1995-2012 IMGT®, the international ImMunoGeneTics information system® |
|||
