Alignment of alleles: Mouse (Mus musculus) TRGC3

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt).

Exon names are shown between parentheses on the first line.
The Cysteines involved in the TR EX1 intrachain disulfide bridge are shown with a larger letter C in purple.
Other Cysteines (including those involved in the interchain disulfide bridge) are shown with a larger letter C in black.
STOP-CODON is indicated by an asterisk.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).

 
                                               1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1   1   2   3   4   5   6   7   8   9  10  11
                                                D   K   K   L   D   A   D   I   S   P   K   P   T   I   F   L   P   S   V 
  M12837  ,TRGC3*01,C7.5 (EX1)               (G)AC AAA AAG CTT GAT GCA GAC ATT TCC CCC AAG CCC ACT ATT TTT CTT CCT TCT GTT
                                                                                                               
  AF037352,TRGC3*02,Cgamma3                  (-)-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                           ___AB_______                                            ________
                                                          15.1    15.3                                                    
                                            12  13  14  15    15.2      16  17  18  19  20  21  22  23  24  25  26  27  28
                                            A   E   T   N   L           H   K   T   G   T   Y   L   C   V   L   E   K   F 
  M12837  ,TRGC3*01,C7.5                   GCT GAA ACA AAT CTC ... ... CAT AAG ACT GGG ACA TAC CTT TGT GTC CTT GAA AAG TTC
                                                                                                               
  AF037352,TRGC3*02,Cgamma3                --- --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ---

                                          _________BC_____________________                            ___________CD_______
                                                                                                      45.1    45.3    45.5
                                            29  30  31  32  33  34  35  36  39  40  41  42  43  44  45    45.2    45.4    
                                            F   P           D   V   I   R   V   Y   W   K   E   K   K   G   N   T   I   L 
  M12837  ,TRGC3*01,C7.5                   TTT CCC ... ... GAT GTC ATA AGG GTG TAT TGG AAA GAA AAG AAA GGC AAT ACC ATC CTG
                                                                                                               
  AF037352,TRGC3*02,Cgamma3                --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                          ________                                _________________________DE_____________
                                              45.7                                84.1    84.3    84.5    84.7    85.6    
                                          45.6      77  78  79  80  81  82  83  84    84.2    84.4    84.6    85.7    85.5
                                                    D   S   Q   E   G   D   M   L   K   T   N   D                         
  M12837  ,TRGC3*01,C7.5                   ... ... GAC TCC CAG GAA GGT GAT ATG CTG AAG ACT AAT GAC ... ... ... ... ... ...
                                                                                                               
  AF037352,TRGC3*02,Cgamma3                ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ...

                                           ________________                                                _EF_____        
                                          85.4    85.2                                                    96.1            
                                              85.3    85.1  85  86  87  88  89  90  91  92  93  94  95  96    96.2  97  98
                                                T   Y   M   K   F   S   W   L   T   V   P   E   R                   S   M 
  M12837  ,TRGC3*01,C7.5                   ... ACA TAC ATG AAG TTT AGC TGG CTT ACT GTG CCT GAA AGG ... ... ... ... TCA ATG
                                                                                                               
  AF037352,TRGC3*02,Cgamma3                ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---

                                                                   _______________________FG___________________________    
                                                                                                                          
                                            99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
                                            G   K   E   H   R   C   I   V   K   H   E   N   N   K   G   G   A   D   Q   E 
  M12837  ,TRGC3*01,C7.5                   GGG AAA GAG CAC AGA TGT ATT GTC AAA CAT GAG AAC AAC AAA GGA GGA GCA GAT CAA GAG
                                              #                               #         T                                 
  AF037352,TRGC3*02,Cgamma3                ---C--- --- --- --- --- --- --- ---C--- --- -C- --- --- --- --- --- --- --- ---

                                                               
                                           119 120 121 122 123 124 125 126
                                            I   F   F   P   T   I   K   K  
  M12837  ,TRGC3*01,C7.5                   ATT TTC TTT CCA ACA ATA AAG AAA G
                                                            P              
  AF037352,TRGC3*02,Cgamma3                --- --- --C --T C-- --- --- --- -



                                             1   2   3   4   5   6   7   8   9  10  11  12  13  14  15
                                            V   A   V   S   T   K   P   T   T   C   W   Q   D   K   N
  M12838  ,TRGC3*01 (2),C7.5 (EX2)          TT GCC GTG AGT ACC AAG CCT ACA ACT TGC TGG CAA GAT AAA AAT

  AF037352,TRGC3*02 (2),Cgamma3             -- --- --- --- --- --- --- --- --- --- --- --- --- --- ---




                                             1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                            D   V   L   Q   L   Q   F   T   I   T   S   A   Y   Y   T   Y   L   L   L   L
  M12839  ,TRGC3*01,C7.5 (EX3)              AT GTG CTG CAG CTC CAG TTC ACG ATC ACC TCT GCC TAC TAC ACC TAC CTT CTC CTG CTC

  AF037352,TRGC3*02,Cgamma3                 -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                            21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                            L   K   S   V   I   Y   L   A   I   I   S   F   S   L   L   R   R   T   S   V
  M12839  ,TRGC3*01,C7.5                   CTC AAG AGT GTG ATC TAC TTG GCC ATC ATC AGC TTC TCT CTG CTT AGA AGA ACA TCT GTC

  AF037352,TRGC3*02,Cgamma3                --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                            41  42  43  44  45  46  47
                                            C   C   N   E   K   K   S   *
  M12839  ,TRGC3*01,C7.5                   TGT TGC AAT GAG AAG AAG TCC

  AF037352,TRGC3*02,Cgamma3                --- --- --- --- --- --- ---


#: frameshift

IMGT notes:

(1) The INSERTION of 1 nucleotide (c) between codons 83/84 and the INSERTION of 1 nucleotide (c) between codons 91/92 lead to frameshifts in EX1.
(2) Defective DONOR-SPLICE in EX2.


Created: 26/02/2001
Last updated: Friday, 27-May-2016 21:03:16 CEST
Authors: Géraldine Folch and Nathalie Bosc

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