When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt). The first nucleotide from an INT-DONOR-SPLICE is underlined (n from ngt).

Exon names are shown between parentheses on the first line.
Cysteine involved in the disulfide bridge are shown in purple.
STOP-CODON is indicated by an asterisk.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).


                                                                                                                                                
                                1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                 E   P   A   T   T   P   G   I   Y   P   L   S   L   P   L   R 
  X82117   IGHA11*01 F  (CH1)   ... ... ... ... gag ccc gcg acc acc cca ggc atc tac ccg ctg agc ctc ccc cta cgt


                                            _____AB_____                                            ____________
                                            15.1    15.3                                                        
                                 13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                 V   S   D   G   N       S   Q   T   V   V   V   G   C   L   I   R   G   F   F 
  X82117   IGHA11*01 F  (CH1)   gtg tca gat ggg aat ... tca cag acc gtg gtc gtc ggc tgc ctg atc cgg ggc ttc ttc


                                _______BC___________________                            _____________CD_________
                                                                                        45.1    45.3    45.5    
                                 30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                 P   L       G   P   L   R   V   S   W   N   V   S   R   E   N   V             
  X82117   IGHA11*01 F  (CH1)   ccc ctg ... ggc cct ctg cgt gtg agc tgg aat gtc agc agg gag aac gtg ... ... ...


                                ____                                ___________________________DE_______________
                                45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                     77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                     S   I   Y   N   F   P   P   A   P   T   G   T   S                       G 
  X82117   IGHA11*01 F  (CH1)   ... agc atc tat aac ttc ccg cct gcc ccg act ggc act tca ... ... ... ... ... ggc


                                ____________                                                ___EF___            
                                    85.2                                                    96.1                
                                85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                 P   Y   T   A   C   S   E   L   I   L   P   D   T   Q   C           L   E   Y 
  X82117   IGHA11*01 F  (CH1)   ccg tat acc gca tgc agc gag ctg atc cta cca gac acg cag tgt ... ... ctt gaa tat


                                                    _________________________FG_________________________                                       
                                100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                 D   S   A   A   C   H   V   E   Y   N               S   V   I   N   E   S   L 
  X82117   IGHA11*01 F  (CH1)   gac agt gca gcc tgc cac gtg gag tac aac ... ... ... tca gta ata aac gag agt ctg


                                                                                   
                                120 121 122 123 124 
                                 P   V   P   F   P  
  X82117   IGHA11*01 F  (CH1)   ccc gtg ccc ttc cca 

                                
                                
                                 1   2   3   4   5   6   7   8   9   10 
                                 D   P   C   E   Q   C   H   C   P   S  
  X82117   IGHA11*01 F  (H)     gat cca tgt gaa caa tgc cac tgc ccc tcc 

                                                                                                                                                
                                1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                         C   E   E   P   S   L   S   L   Q   R   P   D   L   R 
  X82117   IGHA11*01 F  (CH2)   ... ... ... ... ... ... tgc gag gag ccc agc ctg tcc ctg cag cga cca gac ctc aga


                                            _____AB_____                                            ____________
                                            15.1    15.3                                                        
                                 13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                 D   L   L   L           G   S   D   A   S   L   T   C   T   L   R   G   L   K 
  X82117   IGHA11*01 F  (CH2)   gac ctg ctg ctg ... ... ggc tca gac gcc agc ctc acc tgc acc ctg aga ggc ctg aag


                                _______BC___________________                            _____________CD_________
                                                                                        45.1    45.3    45.5    
                                 30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                 D   P       E   G   A   V   F   T   W   E   P   T   N   G   N   E             
  X82117   IGHA11*01 F  (CH2)   gac ccc ... gag gga gcc gtc ttc acc tgg gag ccc aca aac ggg aac gaa ... ... ...


                                ____                                ___________________________DE_______________
                                45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                     77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                     P   V   Q   Q   S   P   Q   R   D   P   C   G                             
  X82117   IGHA11*01 F  (CH2)   ... ccc gtc cag cag agc ccc cag cgt gac ccc tgc ggc ... ... ... ... ... ... ...


                                ____________                                                ___EF___            
                                    85.2                                                    96.1                
                                85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                 C   Y   S   V   S   S   V   L   P   G   C   A   E   P   W           N   A   G 
  X82117   IGHA11*01 F  (CH2)   tgc tac agt gtg tcc agc gtg ctg ccc ggc tgt gcg gag ccc tgg ... ... aac gcg ggg


                                                    _________________________FG_________________________                                      
                                100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                 T   E   F   T   C   T   V   T   H   P   E       I   E   G   S   S   L   T   A 
  X82117   IGHA11*01 F  (CH2)   aca gag ttc acc tgc aca gtc acc cac cct gag ... ata gag ggc agc tcc ctg aca gcc


                                                                                       
                                120 121 122 123 124 125 
                                 T   I   S   K   D   T  
  X82117   IGHA11*01 F  (CH2)   acc atc agc aaa gac aca 

                                                                                                                                               
                                1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                 G   S   L   T   P   P   L   V   H   L   L   P   P   P   S   E 
  X82117   IGHA11*01 F  (CH3)   ... ... ... ... ggc agc ctc acc cca ccc ctg gtc cac ctg ctg ccg ccg ccg tca gaa


                                            _____AB_____                                            ____________
                                            15.1    15.3                                                        
                                 13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                 E   L   A   L           N   A   L   V   T   L   T   C   L   V   R   G   F   S 
  X82117   IGHA11*01 F  (CH3)   gag ttg gcc ctc ... ... aac gcg ctg gtg acg ctg acc tgc ctg gtg cgg ggc ttc agc


                                _______BC___________________                            _____________CD_________
                                                                                        45.1    45.3    45.5    
                                 30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                 P           K   D   V   L   V   S   W   T   N   K   G   V   K   V   P   E   N 
  X82117   IGHA11*01 F  (CH3)   ccc ... ... aag gac gtg ctg gtg tcc tgg aca aac aaa ggc gtg aag gtc ccc gaa aac


                                ____                                ___________________________DE_______________
                                45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                     77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                     S   F   L   V   W   K   P   L   P   E   P   G   Q   D               P   T 
  X82117   IGHA11*01 F  (CH3)   ... agc ttc ctg gtg tgg aag ccc ctg cct gag ccc ggc cag gac ... ... ... ccc acc


                                ____________                                                ___EF___            
                                    85.2                                                    96.1                
                                85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                 T   Y   A   V   T   S   L   L   R   V   P   A   E   D   W           N   Q   N 
  X82117   IGHA11*01 F  (CH3)   acc tac gcc gtc acc agc ctg ctg cgc gtg ccg gcc gag gac tgg ... ... aac cag aat


                                                    _________________________FG_________________________                                       
                                100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                 E   S   Y   S   C   V   V   A   H   E   G       L   A   E   H   F   T   Q   K 
  X82117   IGHA11*01 F  (CH3)   gaa agc tac tcc tgc gtg gtg gcc cat gag ggc ... ctg gcc gag cac ttc acc cag aag


                                                                    ______________________________________CHS__                                
                                120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 
                                 T   I   D   R   L   A               G   K   P   T   H   V   N   V   S   V   V 
  X82117   IGHA11*01 F  (CH3)   acc atc gac cgc ctg gcg ... ... ... ggt aaa ccc acc cat gtc aac gtg tct gtg gtc


                                ____________________________________                                
                                140 141 142 143 144 145 146 147 148 
                                 V   A   D   V   E   A   V   C   Y  
  X82117   IGHA11*01 F  (CH3)   gtg gca gac gta gaa gcc gtg tgc tac