When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt). The first nucleotide from an INT-DONOR-SPLICE is underlined (n from ngt).

Exon names are shown between parentheses on the first line.
Cysteine involved in the disulfide bridge are shown in purple.
STOP-CODON is indicated by an asterisk.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).


                                                                                                                
                                
                                1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                                                                               
  AF314407 IGHA14*01 F  (CH1)   ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ...


                                            _____AB_____                                            ____________
                                            15.1    15.3                                                        
                                 13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                                                                                               
  AF314407 IGHA14*01 F  (CH1)   ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ...


                                _______BC___________________                            _____________CD_________
                                                                                        45.1    45.3    45.5    
                                 30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                                                                                               
  AF314407 IGHA14*01 F  (CH1)   ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ...


                                ____                                ___________________________DE_______________
                                45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                     77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                                                                               
  AF314407 IGHA14*01 F  (CH1)   ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ...


                                ____________                                                ___EF___            
                                    85.2                                                    96.1                
                                85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                                                 I   L   P   P   E   E   C           P   A   G 
  AF314407 IGHA14*01 F  (CH1)   ... ... ... ... ... ... ... .gg atc ctc cca cct gaa gag tgt ... ... ccc gca gga


                                                    _________________________FG_________________________        
                                
                                100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                 N   C   V   A   C   H   V   E   H   N               D   D   E   G   Q   D   L 
  AF314407 IGHA14*01 F  (CH1)   aac tgt gtg gcc tgc cac gtg gaa cac aac ... ... ... gat gac gag ggc cag gac ctc


                                                        
                                
                                120 121 122 123 124 125 
                                 T   V   P   C   P   P  
  AF314407 IGHA14*01 F  (CH1)   act gtg ccc tgc ccc cca 




                                 1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18   
                                 E   D   P   C   K   N   C   P   T   I   S   R   S   R   F   T   A   H         
  AF314407 IGHA14*01 F  (H)     gag gac ccc tgc aaa aac tgc ccc acc atc agc cgc agc cgc ttc acc gcc cac

                                
                                                                                                                                                
                                1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                             C   Q   P   S   L   S   L   Q   R   P   D   L   G  
  AF314407 IGHA14*01 F  (CH2)   ... ... ... ... ... ... ... tgc cag ccc agc ctg tcc ctg cag cgg cca gac ctc ggt
                                
                                
                                            _____AB_____                                            ____________
                                            15.1    15.3                                                        
                                 13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                 D   L
  AF314407 IGHA14*01 F  (CH2)   gac ctg tc  


                                _______BC___________________                            _____________CD_________
                                                                                        45.1    45.3    45.5    
                                 30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
             
  AF314407 IGHA14*01 F  (CH2)   


                                ____                                ___________________________DE_______________
                                45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                     77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                             
  AF314407 IGHA14*01 F  (CH2)   


                                ____________                                                ___EF___            
                                    85.2                                                    96.1                
                                85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
 
  AF314407 IGHA14*01 F  (CH2)   


                                                    _________________________FG_________________________                                        
                              
                                100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
 
  AF314407 IGHA14*01 F  (CH2)   


                                                                                        
                                120 121 122 123 124 125 
  
  AF314407 IGHA14*01 F  (CH2)