When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt). The first nucleotide from an INT-DONOR-SPLICE is underlined (n from ngt).

Exon names are shown between parentheses on the first line.
Cysteine involved in the disulfide bridge are shown in purple.
STOP-CODON is indicated by an asterisk.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).

                               1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                             D   P   V   N   T   R   P   I   L   I   P   L   P   S   P   I   L 
  X82112   IGHA6*01 F  (CH1)    ... ... ... gat ccc gtg aac act aga ccc atc ctc atc cca cta cct agc ccc ata ctt


                                            _____AB_____                                            ____________
                                            15.1    15.3                                                        
                                 13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                 G   P                   G   E   P   V   V   I   G   C   L   I   R   G   F   F 
  X82112   IGHA6*01 F  (CH1)    ggc ccc ... ... ... ... gga gag ccc gtg gtc atc ggc tgc ctg atc cgg ggc ttc ttc


                                _______BC___________________                            _____________CD_________
                                                                                        45.1    45.3    45.5    
                                 30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                 P   L       G   P   L   S   V   T   W   N   T   S   G                         
  X82112   IGHA6*01 F  (CH1)    ccc ctg ... ggc cct ctg agt gtg aca tgg aac acc agc ggg ... ... ... ... ... ...


                                ____                                ___________________________DE_______________
                                45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                     77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                     E   N   L   T   F   P   P   V   Q   S   A   T   S                       S 
  X82112   IGHA6*01 F  (CH1)    ... gag aac ctg acc ttc cca cct gtc cag tct gcc acc tcg ... ... ... ... ... agc


                                ____________                                                ___EF___            
                                    85.2                                                    96.1                
                                85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                 L   Y   T   T   C   S   L   L   R   L   L   A   E   Q   C           P   E   E 
  X82112   IGHA6*01 F  (CH1)    ctg tac acc acg tgc agc ctg ctg agg cta cta gct gag cag tgt ... ... cct gaa gaa


                                                    _________________________FG_________________________                                       
                                100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                 N   S   V   A   C   H   V   E   H   N               Y   D   K   G   Q   H   V 
  X82112   IGHA6*01 F  (CH1)    aat agt gtg gcc tgc cat gtg gag cac aac ... ... ... tac gac aag ggc cag cat gtg


                                                                                        
                                120 121 122 123 124 125 
                                 T   V   P   S   P   P  
  X82112   IGHA6*01 F  (CH1)    acc gtg ccc agc ccc cca 

                                
                                
                                 1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                 E   C   Q   P   P   T   P   G   P   S   D   T   T   T   C   P   C   P   C   P 
  X82112   IGHA6*01 F  (H)      gaa tgc caa ccg cca act cca ggt cct tca gat aca acc acc tgc ccc tgt ccc tgc cct


                                
                                
                                 21  22  23 
                                 S   P   S  
  X82112   IGHA6*01 F  (H)      tcc cca tcc 


                                                                                                                                               
                                1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                         C   G   E   P   S   L   S   L   Q   R   P   F   L   R   
  X82112   IGHA6*01 F  (CH2)    ... ... ... ... ... ... tgt ggg gag ccc agc ctg tcc ctg cag cgg cca ttc ctc agg 


                                            _____AB_____                                            ____________
                                            15.1    15.3                                                        
                                 13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                 D   L   L   L           N   S   N   A   S   L   T   C   T   L   R   G   L   K
  X82112   IGHA6*01 F  (CH2)    gac ctg ctc ctg ... ... aac tcg aac gcc agc ctc acc tgc acc ctg aga ggc ctg aag 


                                _______BC___________________                            _____________CD_________
                                                                                        45.1    45.3    45.5    
                                 30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                 N   P       E   G   A   V   F   T   W   E   P   T   N   G   N   K 
  X82112   IGHA6*01 F  (CH2)    aac ccc ... gag ggc gcc gtc ttc acc tgg gag ccc aca aac ggg aac aaa ... ... ... 


                                ____                                ___________________________DE_______________
                                45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                     77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                     P   V   Q   Q   S   V   Q   S   Y   P   C   G                 
  X82112   IGHA6*01 F  (CH2)    ... ccc gtc cag cag agc gtc cag agt tac ccg tgc ggc ... ... ... ... ... ... ... 


                                ____________                                                ___EF___            
                                    85.2                                                    96.1                
                                85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                 C   Y   S   V   S   S   V   L   P   G   C   A   E   P   W           N   A   G          
  X82112   IGHA6*01 F  (CH2)    tgc tac agt gtg tcc agc gtg ctg ccc ggc tgt gcg gag ccc tgg ... ... aat gcg ggg  


                                                    _________________________FG_________________________                                      
                                100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                 T   E   F   T   C   T   V   T   H   P   E       I   E   G   G   P   L   T   A   
  X82112   IGHA6*01 F  (CH2)    aca gag ttc acc tgc aca gtc acc cac cct gag ... ata gag ggc ggc ccc ctg aca gcc 


                                                                                                   
                                120 121 122 123 124 125 
                                 K   I   S   K   D   T  
  X82112   IGHA6*01 F  (CH2)    aaa atc agc aaa gac aca 



                                                                                                                                               
                                1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                 G   A   I   I   P   P   Q   V   H   L   L   P   P   P   S   E 
  X82112   IGHA6*01 F  (CH3)    ... ... ... ... ggc gcc atc ata cca cct cag gtc cat ctg ctg ccg cca cca tca gag


                                            _____AB_____                                            ____________
                                            15.1    15.3                                                        
                                 13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                 E   L   A   L           N   E   L   V   T   L   T   C   L   V   R   G   F   S 
  X82112   IGHA6*01 F  (CH3)    gag ctg gcc ctc ... ... aac gag ctg gtg aca ctg acc tgc ctg gtg cgg ggc ttc agc


                                _______BC___________________                            _____________CD_________
                                                                                        45.1    45.3    45.5    
                                 30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                 P           K   D   V   L   V   Y   W   T   N   K   G   V   N   V   P   E   N 
  X82112   IGHA6*01 F  (CH3)    ccc ... ... aag gac gtg ctg gtg tac tgg acg aac aaa ggc gtg aat gtc cct gaa aac


                                ____                                ___________________________DE_______________
                                45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                     77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                     S   F   L   V   W   K   P   L   P   E   P   G   Q   E               P   T 
  X82112   IGHA6*01 F  (CH3)    ... agc ttc ctg gtg tgg aag ccc ctg cct gag ccc ggc cag gaa ... ... ... ccc aca


                                ____________                                                ___EF___            
                                    85.2                                                    96.1                
                                85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                 T   Y   A   V   T   S   L   L   R   V   P   A   E   D   W           N   Q   N 
  X82112   IGHA6*01 F  (CH3)    acc tac gcc gtc acc agc ctg ctg cgc gtg ccg gcc gag gac tgg ... ... aac cag aat


                                                    _________________________FG_________________________                                       
                                100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                 E   S   Y   T   C   V   V   G   H   E   G       L   A   E   H   F   T   Q   K 
  X82112   IGHA6*01 F  (CH3)    gaa agc tac acc tgc gtg gtg ggc cat gag ggc ... ctg gcc gag cac ttc acc cag aag


                                                                    ______________________________________CHS__                               
                                120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 
                                 T   I   D   R   L   S               G   K   P   T   H   V   N   V   S   V   V 
  X82112   IGHA6*01 F  (CH3)    acc atc gac cgc ctg tcg ... ... ... ggt aaa ccc acc cac gtc aac gtg tct gtg gtc


                                ____________________________________                               
                                140 141 142 143 144 145 146 147 148 
                                 V   A   D   V   E   G   V   C   Y  
  X82112   IGHA6*01 F  (CH3)    gtg gca gac gtg gaa ggc gtg tgc tac