When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt). The first nucleotide from an INT-DONOR-SPLICE is underlined (n from ngt).

Exon names are shown between parentheses on the first line.
Cysteine involved in the disulfide bridge are shown in purple.
STOP-CODON is indicated by an asterisk.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).


                                                                                                                                               
                                1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                 D   P   A   T   T   P   S   L   F   P   L   S   L   P   C   P 
  X82115   IGHA9*01 F  (CH1)    ... ... ... ... gat ccc gcg acc acc ccc agc ctc ttc ccg ctg agc ctg ccc tgt cct


                                            _____AB_____                                            ____________
                                            15.1    15.3                                                        
                                 13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                 E   C                   A   H   P   V   V   V   G   C   L   I   R   G   F   F 
  X82115   IGHA9*01 F  (CH1)    gag tgt ... ... ... ... gca cat cct gtg gtc gtc ggc tgc ctg atc cgg ggc ttc ttc


                                _______BC___________________                            _____________CD_________
                                                                                        45.1    45.3    45.5    
                                 30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                 P   L       G   P   L   N   V   S   W   N   G   S   E                         
  X82115   IGHA9*01 F  (CH1)    ccc ctg ... ggc cct ctg aat gtg agc tgg aac ggc agc gag ... ... ... ... ... ...


                                ____                                ___________________________DE_______________
                                45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                     77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                     G   G   V   I   F   P   P   V   P   S   P   S   S                       S 
  X82115   IGHA9*01 F  (CH1)    ... ggg ggc gtg atc ttc cct cct gtc ccg tct ccc tcc tca ... ... ... ... ... agc


                                ____________                                                ___EF___            
                                    85.2                                                    96.1                
                                85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                 L   Y   T   T   S   S   L   L   S   L   T   D   D   Q   C           P   R   D 
  X82115   IGHA9*01 F  (CH1)    ctc tac acc aca agc agc ctg ctg agc ctg aca gat gac cag tgt ... ... cct aga gat


                                                    _________________________FG_________________________                                       
                                100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                 G   N   V   T   C   H   V   E   H   N               Y   D   E   G   Q   D   L 
  X82115   IGHA9*01 F  (CH1)    gga aat gtg acc tgc cat gtg gag cac aac ... ... ... tat gat gag ggc cag gat ctg


                                                                                   
                                120 121 122 123 124 
                                 T   V   P   C   Q  
  X82115   IGHA9*01 F  (CH1)    act gtg ccc tgc caa 

                                
                                
                                 1   2   3   4   5   6   7   8   9   10 
                                 D   C   H   C   Y   C   P   P   T   S  
  X82115   IGHA9*01 F  (H)      gac tgc cac tgc tac tgc ccc ccc acc tcc 


                                                                                                                                               
                                1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                         C   G   E   P   S   L   S   L   Q   R   P   D   I   G 
  X82115   IGHA9*01 F  (CH2)    ... ... ... ... ... ... tgc ggg gag ccc agc ctg tcc ctg cag cgg cca gac atc ggg


                                            _____AB_____                                            ____________
                                            15.1    15.3                                                        
                                 13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                 D   L   L   L           E   S   K   A   S   L   T   C   T   L   S   G   L   K 
  X82115   IGHA9*01 F  (CH2)    gac ctg ctc ctg ... ... gaa tcg aag gcc agc ctc acc tgc acc ctg agc ggc ctg aag


                                _______BC___________________                            _____________CD_________
                                                                                        45.1    45.3    45.5    
                                 30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                 D   P       E   G   A   V   F   T   W   E   P   T   N   G   N   E             
  X82115   IGHA9*01 F  (CH2)    gac ccc ... gag ggc gcc gtc ttc acc tgg gag ccc aca aac ggg aac gaa ... ... ...


                                ____                                ___________________________DE_______________
                                45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                     77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                     P   V   Q   Q   S   V   Q   S   Y   P   C   G                             
  X82115   IGHA9*01 F  (CH2)    ... ccc gtc cag cag agc gtc cag agt tac ccg tgc ggc ... ... ... ... ... ... ...


                                ____________                                                ___EF___            
                                    85.2                                                    96.1                
                                85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                 C   Y   S   V   S   S   V   L   P   G   C   A   E   P   W           N   A   G 
  X82115   IGHA9*01 F  (CH2)    tgc tac agt gtg tcc agc gtg ctg ccc ggc tgt gcg gag ccc tgg ... ... aat gcg ggg


                                                    _________________________FG_________________________                                       
                                100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                 T   E   F   T   C   T   V   T   H   P   E       I   E   G   G   S   L   T   A 
  X82115   IGHA9*01 F  (CH2)    aca gag ttc acc tgc aca gtc acc cac cct gag ... ata gag ggc ggc tcc ctg aca gcc


                                                                                       
                                120 121 122 123 124 125 
                                 T   I   S   I   S   R  
  X82115   IGHA9*01 F  (CH2)    acc atc agc atc agc aga 

                                                                                                                                               
                                1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                 G   S   L   T   P   P   Q   V   H   L   L   P   P   P   T   E 
  X82115   IGHA9*01 F  (CH3)    ... ... ... ... ggc agc ctc acc cca ccc cag gtc cac ctg ctg cca ccg ccg act gag


                                            _____AB_____                                            ____________
                                            15.1    15.3                                                        
                                 13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                 E   L   A   L           N   E   Q   V   T   L   T   C   L   V   Q   G   F   S 
  X82115   IGHA9*01 F  (CH3)    gag ctc gcc ctg ... ... aat gag cag gtg acg ctc acc tgc ctg gtg cag ggc ttc agc


                                _______BC___________________                            _____________CD_________
                                                                                        45.1    45.3    45.5    
                                 30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                 P           K   D   V   L   V   S   W   T   H   N   G   T   L   V   V   P   K 
  X82115   IGHA9*01 F  (CH3)    ccc ... ... aag gac gtg ctg gtg tcc tgg aca cac aac ggc acc ctg gtg gtc ccc aaa


                                ____                                ___________________________DE_______________
                                45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                     77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                 D   S   Y   L   V   W   K   P   L   P   E   P   G   Q   D               P   T 
  X82115   IGHA9*01 F  (CH3)    gac agc tac ctg gtg tgg aag ccc ctg cct gag ccc ggc cag gac ... ... ... ccc acc


                                ____________                                                ___EF___            
                                    85.2                                                    96.1                
                                85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                 T   Y   A   V   T   S   L   L   R   V   S   A   E   D   W           N   Q   G 
  X82115   IGHA9*01 F  (CH3)    acc tac gct gtc acc agc ctg ctg cgc gtg tcg gcc gag gac tgg ... ... aac cag ggg


                                                    _________________________FG_________________________                                       
                                100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                 D   S   Y   S   C   V   V   G   H   E   G       L   A   E   H   F   T   Q   K 
  X82115   IGHA9*01 F  (CH3)    gac agc tac tcc tgc gtg gtg ggc cat gag ggc ... ctg gcc gag cac ttc acc cag aag


                                                                    ______________________________________CHS__                               
                                120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 
                                 T   I   D   R   Q   A               G   K   P   T   H   V   N   V   S   V   V 
  X82115   IGHA9*01 F  (CH3)    acc atc gac cgc caa gcg ... ... ... ggt aaa ccc acc cac gtc aac gtg tct gtg gtc


                                ____________________________________                               
                                140 141 142 143 144 145 146 147 148 
                                 V   A   D   V   E   A   V   C   Y  
  X82115   IGHA9*01 F  (CH3)    gtg gca gac gtg gaa gcc gtg tgc tac