When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

                                                               
                                    
                                      1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                      Q   E   Q   L   V   E   S   G   G       G   L   V   T   T   G   E   S   L   K 
  M93184   IGHV1S46*01 P             cag gag cag ctg gtg gag tcc ggg gga ... ggc ctg gtc acg act ggg gaa tct ttg aaa


                                                             ___________________CDR1-IMGT____________________        
                                     
                                      21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                      L   F   R   K   A   S   G   F   T   I   S               S   S   Y   W   I   C 
  M93184   IGHV1S46*01 P             ctc ttc cgc aaa gcc tct gga ttc acc atc agt ... ... ... agc agc tac tgg ata tgc


                                                                                                 _______________CDR2-

                                     
                                      41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                      W   V   R   Q   A   P   G   K   G   P   E   W   I   G   Y   I   S   S   A     
  M93184   IGHV1S46*01 P             tgg gtc cgc cag gct cca ggg aag ggg ccg gag tgg atc gga tac att agt agt gct ...


                                     IMGT________________                                                            
                                     
                                      61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80 
                                              G   S   T   N   Y   T   S   W   V   N       G   *   I   I   I   S   S 
  M93184   IGHV1S46*01 P             ... ... ggt agc aca aac tac acc agc tgg gtg aat ... ggc tga atc atc atc tcc agc


                                     
                                     
                                      81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100 
                                      N   N   A   Q   K   T   L   Y   R   Q   M   N   S   L   T   A   R   D   R   A 
  M93184   IGHV1S46*01 P             aac aac gcc cag aaa acg ctg tat cgg caa atg aac agt ctg aca gcc agg gat agg gcc


                                                     CDR3-IMG

                                     
                                     101 102 103 104 105 106 
                                      L   Y   F   C   A   G  
  M93184   IGHV1S46*01 P             ctg tat ttc tgt gca gga 

Legend:

*: STOP_CODON mutation

This alignment of allele is generated by IMGT/OutilAllele.