When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt). The first nucleotide from an INT-DONOR-SPLICE is underlined (n from ngt).

Exon names are shown between parentheses on the first line.
Cysteine involved in the disulfide bridge are shown in purple.
STOP-CODON is indicated by an asterisk.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).

                                
                                
                                 1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                  R   D   P   V   A   P   S   V   L   L   F   P   P   S   K   E 
  X00232   IGKC2*01  F           ... ... ... ... cgt gat cca gtt gcg cct tct gtc ctc ctc ttc cca cca tct aag gag
                                                                                                               
  V00885   IGKC2*01  F           ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                               
  X05801   IGKC2*01  F           ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                               
  X05800   IGKC2*02  F           ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                               
  X56061   IGKC2*03  F   (1)     ... ... ... ... --- --- --- --- --a --- --- --- --- --- --- --- --- --- --- ---
                                                                                                               
  M22543   IGKC2*03  F           ... ... ... ... --- --- --- --- --a --- --- --- --- --- --- --- --- --- --- ---
                                                                                                               
  K01280   IGKC2*04 (F)  (2)     ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                             _____AB_____                                            ____________
                                             15.1    15.3                                                        
                                  13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                  E   L   T               T   G   T   A   T   I   V   C   V   A   N   K   F   Y 
  X00232   IGKC2*01  F           gag ctg aca ... ... ... act gga aca gcc acc atc gtg tgc gtg gcg aat aaa ttc tat
                                                                                                               
  V00885   IGKC2*01  F           --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                               
  X05801   IGKC2*01  F           --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                               
  X05800   IGKC2*02  F           --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                               
  X56061   IGKC2*03  F   (1)     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                               
  M22543   IGKC2*03  F           --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                               
  K01280   IGKC2*04 (F)  (2)     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                 ___________BC_______________                            _____________CD_________
                                                                                         45.1    45.3    45.5    
                                  30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6     
                                  P           S   D   I   T   V   T   W   K   V   D   G   T   T   Q   Q   S     
  X00232   IGKC2*01  F           ccc ... ... agt gac atc acc gtc acc tgg aag gtg gat ggc acc acc caa cag agc ...
                                                                                                               
  V00885   IGKC2*01  F           --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                               
  X05801   IGKC2*01  F           --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                               
  X05800   IGKC2*02  F           --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                               
  X56061   IGKC2*03  F   (1)     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                               
  M22543   IGKC2*03  F           --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                               
  K01280   IGKC2*04 (F)  (2)     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...


                                 ____                                ___________________________DE_______________
                                 45.7                                84.1    84.3    84.5    84.7    85.6    85.4     
                                      77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                      G   I   E   N   S   K   T   P   Q   S   P   E   D                       N 
  X00232   IGKC2*01  F           ... ggc atc gag aac agt aaa aca ccg cag agc ccc gaa gac ... ... ... ... ... aat
                                                                                                               
  V00885   IGKC2*01  F           ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---
                                                                                                               
  X05801   IGKC2*01  F           ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---
                                                                                                               
  X05800   IGKC2*02  F           ... --- --- --- --- --- --- --- --- --- --- --t --- --- ... ... ... ... ... ---
                                                                                                               
  X56061   IGKC2*03  F   (1)     ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---
                                                                                                               
  M22543   IGKC2*03  F           ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---
                                                                                                               
  K01280   IGKC2*04 (F)  (2)     ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---


                                 ____________                                                ___EF___    
                                     85.2                                                    96.1        
                                 85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99
                                  T   Y   S   L   S   S   T   L   S   L   T   S   A   Q   Y           N   S   H 
  X00232   IGKC2*01  F           acc tac agc ctg agc agc act ctg tca ctg acc agc gca cag tac ... ... aac agc cac
                                                                                                               
  V00885   IGKC2*01  F           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                               
  X05801   IGKC2*01  F           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                               
  X05800   IGKC2*02  F           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                               
  X56061   IGKC2*03  F   (1)     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                               
  M22543   IGKC2*03  F           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                                                                                               
  K01280   IGKC2*04 (F)  (2)     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                     _________________________FG________________________
                                
                                 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                  S   V   Y   T   C   E   V   V   Q   G   S               A   S   P   I   V   Q 
  X00232   IGKC2*01  F           agc gtg tac acc tgc gag gtg gtc caa ggc tca ... ... ... gcc tca ccg atc gtc cag
                                                                                                               
  V00885   IGKC2*01  F           --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- ---
                                                                                                               
  X05801   IGKC2*01  F           --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- ---
                                                                                                               
  X05800   IGKC2*02  F           --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- ---
                                                                                                               
  X56061   IGKC2*03  F   (1)     --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- ---
                                                                                                               
  M22543   IGKC2*03  F           --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- ---
                                                                                                  L             
  K01280   IGKC2*04 (F)  (2)     --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- -t- --- --- ---


                                
                                
                                 120 121 122 123 124 125 126
                                  S   F   N   R   G   D   C  
  X00232   IGKC2*01  F           agc ttc aac agg ggt gac tgc 
                                                            
  V00885   IGKC2*01  F           --- --- --- --- --- --- --- 
                                                            
  X05801   IGKC2*01  F           --- --- --- --- --- --- --- 
                                                            
  X05800   IGKC2*02  F           --- --- --- --- --- --- --- 
                                                            
  X56061   IGKC2*03  F   (1)     --- --- --- --- --- --- --- 
                                                            
  M22543   IGKC2*03  F           --- --- --- --- --- --- --- 
                                                            
  K01280   IGKC2*04 (F)  (2)     --- --- --- --- --- --- --- 
  
IMGT notes:
(1) This allele was identified in the subspecies sp.algirus.
(2) This allele was identified in the strain : Basilea.