When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).


                                       
                                       
                                        1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                        D   P   V   L   T   Q   T   P   S   S   A   C   E   P   V   G   G   T   V   T 
  AF135624 IGKV1S49*01 [F] (1)         gac cct gtg ctg acc cag act cca tct tcc gcg tgt gaa cct gtg gga ggc aca gtc acc


                                                               ___________________CDR1-IMGT____________________        
                                       
                                        21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                        I   K   C   Q   A   S   E   S   I                           S   S   R   L   A 
  AF135624 IGKV1S49*01 [F] (1)         atc aag tgc cag gcc agt gag agc att ... ... ... ... ... ... agt agt aga tta gcc


                                                                                                   _______________CDR2-
                                       
                                        41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                        W   Y   Q   Q   K   P   G   Q   S   P   K   L   L   I   Y   S   A             
  AF135624 IGKV1S49*01 [F] (1)         tgg tat cag cag aaa cca ggg cag tct ccc aag ctc ctg atc tat tct gca ... ... ...


                                       IMGT________________                                                            
                                       
                                        61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80 
                                                        S   T   L   A   S   G   V   P       S   R   F   K   G   S   G 
  AF135624 IGKV1S49*01 [F] (1)         ... ... ... ... tcc act ctg gca tct ggg gtc cca ... tcg cgg ttc aaa ggc agt gga


                                       
                                       
                                        81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100 
                                                S   G   T   E   Y   T   L   T   I   S   D   L   E   C   A   D   A   A 
  AF135624 IGKV1S49*01 [F] (1)         ... ... tct ggg aca gag tac act ctc acc atc agc gac ctg gag tgt gcc gat gct gcc


                                                       _________________CDR3-IMGT____________________    
                                       
                                       101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 
                                        T   Y   Y   C   Q   N   N   N   G   G   S   G   S   T   G  
  AF135624 IGKV1S49*01 [F] (1)         act tac tac tgt caa aac aat aat ggt ggt agt ggt agt act ggt tc   °


Legend:

°: genomic DNA, but not known as being germline or rearranged.

IMGT note:
(1) V-REGION is partial: partial CDR3-IMGT.