Only the *01 allele of each functional, ORF and in-frame pseudogene V-REGION is shown.
Dots indicate gaps according to the IMGT unique numbering. Blanks at the 5' and/or 3' end indicate partial sequences.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
For C-REGIONs, letters in bold correspond to additional positions in the IMGT unique numbering.
For C-REGIONs, letters between parentheses correspond to amino acids resulting from the splicing.
One pseudogene has been included (1)
_____________________________________________________________________________________________________________________________________________________ IGIV FR1-IMGT CDR1-IMGT FR2-IMGT CDR2-IMGT FR3-IMGT CDR3-IMGT genes (1-26) (27-38) (39-55) (56-65) (66-104) (105-116) ___________________________ __________________________ ____________ _________________ __________ _______________________________________ ____________ 1 10 20 30 40 50 60 70 80 90 100 110 .........|.........|...... ...|........ .|.........|..... ....|..... ....|.........|.........|.........|.... .....|..... AY165791,IGIV1S1 QATVTQTPAVKSALPGETVTINCRTN PAVYYYSSYGHY LHWYQQKPGEAPKLLIK FAN....... QLQSGIP.ARFSGSG..SGSDFTLTISGVQTEDAGDYYC QSYHSGVCS... AY165792,IGIV1S2 QVTVTQTPAVKSALPGETVTINCRTN PAVYKGSSGES. LHWYQQKPGEAPKLLIK FAN....... QLQSGIP.ARFSGSG..SGSDFTLTISGVQTEDAGDYYC QSYHSGVCS... AY165787,IGIV1S3 QITVTQTPAVKSALPGETVTINCRTS QAGINDNW.... LHWYQQKPGEAPKLLIL YAN....... RLQSGFP.ARFKGSG..SRSDFTLTITGVLTEDAGDYYC QSYHYISSTDLF AY165790,IGIV1S4 QVTVTQTPAVKSALPGETVTINCRTS QAVYSSNY.... LHWYQQKPGEAPKLLIK IAN....... QLQSGFP.ARFSGSG..SGSDFTLTISGVQTEDAGDYYC QSFHCPSSCVF. #c L25539 ,IGIV1S5 WYQQEPGEAPKLLII KAN....... QLQSGIP.ARFSGSG..SGSDFTLTISGVQTEDAGDYYC QSVHCPSSCV #c L25540 ,IGIV1S6 WYQQEPGEAPKLLIK YVK....... QLQSGFP.ARFSGSG..SGSDFTLTISGVQTEDTGDYYC QSHHEITGYW #c U25703 ,IGIV1S7 SVSPGQSVTLTCTSS QGVSNN...... LNWYLQKPGEAPKLLIY YAS....... NRQSGIP.DRFSGSG..SGSQFSLKISGVQSEDAGDYYC PQYSSFP #c U25704 ,IGIV1S8 EIVLTQSPGSQSVSPGQSVTLTCTSS QGVNNY...... LAWYLQKPGEAPKLLIY RAS....... NRQSGIP.DRFSGSG..SGS*FSLKISGVQSEDAGDYYC QQYSSFP #c U25705 ,IGIV1S9 EIVLTQSPGSQSVSPGQSVTLTCRAS QGVYDD...... LQWYLQKPGEAPKLLIY NDV....... TRFTGVP.DRFSGSG..RGTEFSLTISGVQSEDAGDYYC QQSETTP #c: rearranged cDNAIMGT note:
| (1) | IGIV1S8: In frame STOP-CODON at codon 86 in FR3-IMGT (positions 256-258 in IMGT unique numbering). |
Created: 25/03/2003
Author: Nathalie Bosc
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
|
IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr |
|
|
|
|
Citing IMGT © Copyright 1995-2012 IMGT®, the international ImMunoGeneTics information system® |
|||
