Only a few examples of Teleostei IGI C-DOMAINs are shown.
The protein display numbering is according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
Only the *01 allele of each functional, ORF and in-frame pseudogenes C-REGION is shown.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
For C-REGIONs, letters in bold correspond to additional positions in the IMGT unique numbering.
For C-REGIONs, letters between parentheses correspond to amino acids resulting from the splicing.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CH-S and in pages edited before 14/10/2009).
Only a few examples of Teleostei IGI C-DOMAINs are shown.
_____________________________________________________________________________________________________________________________________________________________________________________________
IGLC, IGKC and IGIC
genes
_____________________________________________________________________________________________________________________________________________________________________________________________
A AB B BC C CD D DE E EF F FG G CH-S
--------------> ----------> ------> -------> -----------> -------> ---------->
1 10 15 16 20 23 30 36 39 41 45 77 84 85 89 96 97 104 110 118 121 130 140 150
7654321|........|....|123|...|...... ...|.....| |.....|1234567|......|12345677654321|..........|12|....... .....|....... ..|.........|.........|.........|
IGLC
Homsap X51755 ,IGLC1 (G)QPKANPTVTLFPPSSEELQ...ANKATLVCLIS DFYP..GAVT VAWKADGSPVKA..GVETTKPSKQSN......NKYAASSYLSLTPEQW..KSHRSYSC QVTHE....GSTV EKTVAPTECS
Homsap J00253 ,IGLC2 (G)QPKAAPSVTLFPPSSEELQ...ANKATLVCLIS DFYP..GAVT VAWKADSSPVKA..GVETTTPSKQSN......NKYAASSYLSLTPEQW..KSHRSYSC QVTHE....GSTV EKTVAPTECS
Homsap K01326 ,IGLC3 (G)QPKAAPSVTLFPPSSEELQ...ANKATLVCLIS DFYP..GPVT VAWKADSSPVKA..GVETTTPSKQSN......NKYAASSYLSLTPEQW..KSHKSYSC QVTHE....GSTV EKTVAPTECS
Homsap J03011 ,IGLC6 (G)QPKAAPSVTLFPPSSEELQ...ANKATLVCLIS DFYP..GAVK VAWKADGSPVNT..GVETTTPSKQSN......NKYAASSYLSLTPEQW..KSHRSYSC QVTHE....GSTV EKTVAPAECS
Homsap X51755 ,IGLC7 (G)QPKAAPSVTLFPPSSEELQ...ANKATLVCLVS DFYP..GAVT VAWKADGSPVKV..GVETTKPSKQSN......NKYAASSYLSLTPEQW..KSHRSYSC RVTHE....GSTV EKTVAPAECS
Musmus J00587 ,IGLC1 (G)QPKSSPSVTLFPPSSEELE...TNKATLVCTIT DFYP..GVVT VDWKVDGTPVTQ..GMETTQPSKQSN......NKYMASSYLTLTARAW..ERHSSYSC QVTHE....GHTV EKSLSRADCS
Musmus J00595 ,IGLC2 (G)QPKSTPTLTVFPPSSEELK...ENKATLVCLIS NFSP..SGVT VAWKANGTPITQ..GVDTSNPTKEGN.......KFMASSFLHLTSDQW..RSHNSFTC QVTHE....GDTV EKSLSPAECL
Musmus J00585 ,IGLC3 (G)QPKSTPTLTMFPPSPEELQ...ENKATLVCLIS NFSP..SGVT VAWKANGTPITQ..GVDTSNPTKEDN.......KYMASSFLHLTSDQW..RSHNSFTC QVTHE....GDTV EKSLSPAECL
Musspr M16554 ,IGLC2 (G)QPKSTPTLTVFPPSSEELK...ENKATLVCLIS NFSP..SGVT VAWKANGTPITQ..GVDTSNPTKEGN.......KFMASSFLHLTSDQW..RSHNSFTC QVTHE....GDTV EKSLSPAECL
Musspr AF357974,IGLC5 (G)QPKATPSVNLFPPSSEELK...TKKATLVCMIT EFYA..TAVR MAWKADGTPITQ..DVETTQPPKQS........DNMASSYLLFTAEAW..ESHSSYSC HVTHE....GNTV EKNLSRAECS
IGKC
Homsap V00557 ,IGKC (G)TVAAPSVFIFPPSDEQLK...SGTASVVCLLN NFYP..REAK VQWKVDNALQSG..NSQESVTEQDSKD.....STYSLSSTLTLSKADY..EKHKVYAC EVTHQG..LSSPV TKSFNRGEC
Musmus V00807 ,IGKC (G)ADAAPTVSIFPPSSEQLT...SGGASVVCFLN NFYP..KDIN VKWKIDGSERQN..GVLNSWTDQDSKD.....STYSMSSTLTLTKDEY..ERHNSYTC EATHKT..STSPI VKSFNRNEC
Musspr M21796 ,IGKC (G)ADAAPTVSIFPPSSEQLT...SGGASVVCFLN NFYP..RDIN VKWKIDGSERQN..GVLNSWTDQDSKD.....STYSMSSTLTLTKDEY..ERHNSYTC EATHKT..STSPI VKSFNRNEC
IGIC
Danrer AF246185,IGIC1S1 c (T)VSPPQVSVLQPSSAEISS..KRTATLLCVAN KGFP..SDWR LVWKVLKPDGSSSSGGQESSSAGLLEKD.....GLYSWSSSLTLTEQQW..MESASVSC EATRSG.QPALTA GDTVRRQQCSE
Danrer AF246162,IGIC2S1 c(st) (D)AAAAPPVLTILRPSSREELS..SSKVTLLCLIN HMSV..AFAD VRWLVNGNSVTE...GVFTGSAEQQPD......HKFKSSSSLTIQRSEW..DKDRELTC EATVA....SKTS RASIRKSECSD
Danrer AF246181,IGIC2S2 c (D)AAAAPPVLTILRPSSREELS..SSKVTLLCLIN HMSV..ASAD VRWLVNGNSVTE...GVFTGSAEQQPD......HKFKSSSSLTIQRSEW..DKDRELTC EATVA....SKTS RASIRKSECSD
Danrer AF246193,IGIC3S1 c (T)GSPVKPSVSLLGSSSLQSS...GDSAALLCLLS SYSP..PGAK VSWTRDGSELSE...GFLTSAESQQDG.......RYSCTSVLKLKREEW..EKREPYAC RVTHA....GGDQ EIPFPKC
c: cDNA sequence
(st): sterile transcript
Danrer: Danio rerio (Zebrafish)
Homsap: Homo sapiens (Human)
Musmus: Mus musculus (House mouse)
Musspr: Mus spretus (Western wild mouse)
Created: 07/03/2003
Author: Delphine Guiraudou
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
|
IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr |
|
|
|
|
Citing IMGT © Copyright 1995-2012 IMGT®, the international ImMunoGeneTics information system® |
|||
