Protein display: Spotted ratfish (Hydrolagus colliei) IGH C-REGIONs

The IGHC protein display numbering is according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.

Only the *01 allele of each functional, ORF and in-frame pseudogenes C-REGION is shown.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).

_____________________________________________________________________________________________________________________________________________________________________________________________

      IGHC
      genes

_____________________________________________________________________________________________________________________________________________________________________________________________

                                  A                 B         BC         C               D                     E              F               G
                            --------------->    ---------->             ----->        ----------->       -------------->  ------------->   ---------->

                             1       10   15  16  20 23      30    36 39 41 45      77     84             85  89     96 97    104   110 114   120       130       140       150
                      7654321|........|....|123|...|...... ...|.....|  |.....|1234567|......|12345677654321|..........|12|............|...|.....|.........|.........|.........|
CH1
AF003844,IGHM1*01  (D)IVKPKPSPPVVILLQPSAEDIAM..LRPATAVCLIF SFEP..DKLS  VKWLKNWQPVTS..GVVTSPSVKEDN......GTFSISSRLTVPAREW..RNGGVYICQVSHS....PTDTTIVKSITMPT
AF003862,IGHM2*01      (A)VPTPPSLYALLPSCGPSTS..RGSVTFWCLAT NYNP..EPAT  FSWTSNGRSITD..QVKTYPSVLNKN......GLYTLSSQLTIAESQM...DNSNIRCKVKSS....SWPDVDIPLP
AF003839,IGHM3*01c     (A)TPTAPSLYALLPTCGSPPL..EGQLTFGCLAA DFSP..EPAT  FSWTSKGHPIAN..KGQVKSYPPVLSK....AGFYTASSQLTIEASQV...DIFNLCCQVKSS....IWLDGDICFP
AF004359,IGHM4*01c     (A)VPTPPSLYALLPSCGPSTS..RGSVTFWCLAT NYNP..EPAT  FSWTSNGRSITD..QVKTYPSVLNKN......GLYTLSSQLTIAESQM...DNSNIRCKVKSS....SWPDVDTPLP
AF004360,IGHM5*01c     (A)VPTPPSLYALLPSCGPSTS..RGSVTFWCLAT NYNP..EPAT  FSWTSNGRSITD..QVKTYPSVLNKN......GLYTLSSQLTIAESQM...DNSNIRCKVKSS....SWPDVDIPLP
AF003853,IGHM8*01c (D)IVKPKPSPPGVILLPPSPEDMAM..LRPATAVCLIF SFEP..DKLS  VKWFKDWQPVTS..GVVTSPSVKEDN......GTYSISSRLTVPAREW..RNGGVYICQVSHS....PTDTTIVQSITMPT

CH2
AF003845,IGHM1*01  (V)DEIQEPSPPVVILTQPSPEDIAI..HKPGIAVCLIS GFRP..DELT  VKWLKDWEPITS..GVETSPSVKEDN......GTFTTSSRLTVLAREW..RSGSVYTCQVSHS....PTQTYIVKNITKSS
AF003863,IGHM2*01  (V)ELLQDPSPPVVILTQTSPEDITL..NKQATAVCLIS SFRP..DKLR  VDWLKDWQIITS..GVVTSLSVKEDN......GTFSTSSRLTVPARDW..RNDTVYTCQVTHV....PTQTIIVKNITKSS
AF003839,IGHM3*01c    (V)VQPSPPVVLLTQTSPEDIAL..INQATLLCSVS GFRP..DKLI  VDWLKDGKAVTS..GIETSPSLKDN...... GNFSTDSRLTIPAKDW..RWDVVYSCRVTHD....PSQTLIIKNITNWNP
AF004359,IGHM4*01c (V)ELLQAPSPPVVILTQTSPEDITL..NKQATAVCLIS SFRP..DKLR  VDWLKDWQIVTS..GVVTSLSVKEDN......GTFSTSSRLTVPARDW..RNDAVYTCQVTHV....PTQTIIVKNITKSS
AF004360,IGHM5*01c (V)ELLQDPSPPVVILTQTSPEDITL..NKQATAVCLIS SFRP..DKLR  VDWLKDWQIITS..GVVTSLSVKEDN......GTFSTSSRLTVPARDW..RNDAVYTCQVTHV....PTQTIIVKNITKSS

CH3
AF003846,IGHM1*01   (D)CEDPTGNVKIYFLPLSPKQVLM..ESSVTLTCVVD NAPL...DVN  VSWTQGEKQL....SGYGKPSVTER.........HEVMSELNVSTEDW..KSGKEFFCVASHED..MPTPVREKIFQRT
AF003864,IGHM2*01    (E)CVDHGDVKVSFLPPSQKQVLM..ESSVILTCIVT NSPL...DVN  VDWTQGQTTL....QSGHGKQSATE........PQEVISELNISTHDW..ISGKEFNCIASHED..MPTPIREKIVKRE
AF003839,IGHM3*01c     (E)CLGEVKVSFLPPSPKQVLL..GDTVTLTCVVT EAPS...GVN  VTWTQGHMAR....QSARESRSA...........QRVTSELNVSTREW..NGGKEFECVANHVD..MLTPKRGTISKKP
AF004359,IGHM4*01c   (E)CVDHGDVKVSFLPPSQKQVLM..ESSVILTCIVT NSPL...DVN  VDWTQGQTTL....QSGHGKQSATE........PQEVISELNISTHDW..ISGKEFNCIASHED..MPTPIREKIVKRE
AF004360,IGHM5*01c   (E)CVDHGDVKVSFLPPSQKQVLM..ESSVILTCIVT NSPL...DVN  VDWTQGQTTL....QSGHGKQSATE........PQEVISELNISTHDW..ISGKEFNCIVSHED..MPTPIREKIVKRE

CH4
AF003847,IGHM1*01     (V)DHTKQPSVYILLPSAAELTA..QQSVTLTCLVK DFAP..KEIF  VQWTVDDKEIDVS.NYKNTELMADSAD.....RNYSMYSMLTISAGEW..GRGFSYSCIVGHET.FALKTLTRTVNKSSGKPSFVNISLVLMDAVNACQ*  
AF003865,IGHM2*01     (V)LHMKQPSVYLLLPSAEELST..HQSVTLTCLVK DFTP..KEIF  VEWAVNDQVIDAS.NYMNTEVMAASAD.....HNYSMYSMLTISAEDW..DRGHTYSCVVGHES.FPLKTLTRAVNKCSGKPSFVNISLVQMDTVNACQ*
AF003839,IGHM3*01c    (D)QDTNRPSVYLLLPSPEELSA..HQWVTLTCLVK EFAP..KEIF  VEWAVNDQAIDAS.QYTNTEAMAANTS.....HNYSMYSMLSVSAGDW..DKGNTYSCVVGHRS.FNSSKTLTRYVNKTSGKPTFVNVSLVLVDTVKTCQ*
AF004359,IGHM4*01c    (V)LHMKQPSVYLLLPSAEELST..HQSVTLTCLVK DFTP..KEIF  VEWAVNDQVIDAS.NYMNTEVMAASAD.....HNYSMYSMLTISAEDW..DRGHTYSCVVGHES.FPLKTLTRAVNKCSGKPSFVNISLVQMDTS
AF004360,IGHM5*01c    (V)LHMKQPSVYLLLPSAEELST..HQSVTLTCLVK DFTP..KEIF  VEWAVNDQVIDAS.NYMNTEVMAASAD.....HNYSMYSMLTISAEDW..DRGHTYSCVVGHES.FPLKTLTRAVNKC
AF003852,IGHM6*01        LHMKQPSVYLLLPSAEELST..HQSVTLTCLVK DFTP..KEIF  VEWAVNDQVIDAS.NYMNTEVMAASAD.....HNYSMYSMLTISAEDW..DRGHTYSCVVGHES.FPLKTLTRAVNKCSGKPSFVNISLVQMDTVNA

                                                M1
AF004360,IGHM5*01c       (S)DFPTEMMLEGFPPDESGNLWPTASTFIILFF
                         CONNECTING_REGION    | TRANSMEMBRANE-REGION       
         
c: cDNA sequence


Created: Friday, 27-May-2016 21:03:28 CEST
Author: Dominique Scaviner

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209 Full text Cover; Ruiz, M. et al., Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219 Full text; Lefranc, M.-P., Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207 Full text; Lefranc, M.-P., Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085 Full text; Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

CNRS Université de Montpellier European Commission
IMGT® Founder and Executive Director Emeritus:
Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
IMGT® Director:
Sofia Kossida Sofia.Kossida@igh.cnrs.fr
Bioinformatics manager:
Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr
Computer manager:
Patrice Duroux Patrice.Duroux@igh.cnrs.fr
Webmaster:
Amélie Houles

Citing IMGT | Warranty disclaimer and copyright notice | Privacy policy and advertisement policy

© Copyright 1995-2017 IMGT®, the international ImMunoGeneTics information system®