Two pseudogenes IGHV2S2 and IGHV3S1 have been included (1).
Only the *01 allele of each functional, ORF and in-frame pseudogene V-REGION is shown.
Dots indicate gaps according to the IMGT unique numbering. Blanks at the 5' and/or 3' end indicate partial sequences.
Two pseudogenes IGHV2S2 and IGHV3S1 have been included (1).
___________________________________________________________________________________________________________________________________________________ IGHV FR1-IMGT CDR1-IMGT FR2-IMGT CDR2-IMGT FR3-IMGT CDR3-IMGT gene (1-26) (27-38) (39-55) (56-65) (66-104) (105-115) __________________________ __________________________ ____________ _________________ __________ _______________________________________ ___________ 1 10 20 30 40 50 60 70 80 90 100 110 .........|.........|...... ...|........ .|.........|..... ....|..... ....|.........|.........|.........|.... .....|..... J03616 ,IGHV1S1 QVQLVESGG.DVKKPGDSLRLSCKAS GYTFSGYT.... MYWVRQAPGKGLEWVSR IYDDGSDV.. SYADTVK.GRFTISRDNAKNLLYLQMSNLKPEDTGRYYC AR X61312 ,IGHV2S1 GQSLTSSDS.VVKKPGESVTLSCTAS GFSMSSYW.... MGWIRQKPGKALEWIGQ ISGSTV.... YYAQSLQ.GQFSITTDTSKNMLHLEVKSLKTEDTAVYYC ARD X65266 ,IGHV2S2 VVSL*PPQS.ML*KTGRTVILSCTVS GISMSSHW.... MHWIRQ*PGKGLEWIGC IDTGSSV... YYAQSLK.GRLSITKDTSKNMLYLKVIDLKTEYTAVYYC ARD X61313 ,IGHV3S1 LT*V*RSES.VIIKPGNNHKLTCTFS GIDVGAAD.... ISWTRQAEGKALEWISY ISAPSGSSK. YYFKTVE.GRFTISRDKSKMQVYLHMTNLQTEDTAVYYC ARK
IMGT note:
| (1) | IGHV2S2 | In frame STOP-CODONs (positions 13-15 and 37-39) at codons 5 and 13 in FR1-IMGT and (position 133-135) at codon 45 in FR2-IMGT. |
| IGHV3S1 | In frame STOP-CODONs (positions 7-9 and 13-15) at codons 3 and 5 in FR1-IMGT. |
Created: 06/03/2002
Author: Nathalie Bosc
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
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