The TRC protein display numbering is according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
For C-REGIONs, letters in bold correspond to additional positions in the IMGT unique numbering.
For C-REGIONs, letters between parentheses correspond to amino acids resulting from the splicing.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CH-S and in pages edited before 14/10/2009).
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TR C-GENEs
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A AB B BC C CD D DE E EF F FG G
--------------> ----------> ------> -------> -----------> -------> ---------------->
1 10 15 16 20 23 26 30 36 39 41 45 77 84 85 89 96 97 104 110 115 118 121 130
87654321|........|....|123|...|...... ...|.....| |.....|1234567|......|12345677654321|..........|12|....... .....|.123456654321...|.. ..|.........|....
EX1
M64239 ,TRAC (X)IQNPEPAVYQLKDPR........SQDSTLCLFT DFDS...QIN VPKTMES.......GTFITDKTVLDMKAM.DSKSNGAIAWSNQT..........SFTC QDIFKE.............TNATYP SS
M26053 ,TRBC1 (E)DLRNVTPPKVSLFEPSKAEIAN..KQKATLVCLAR GFFP..DHVE LSWWVNGKEVHS..GVSTDPQAYKESN.....YSYCLSSRLRVSATFWH.NPRNHFRC QVQFHGLSEEDKWPEGSPKPVTQNI SAEAWGRA
M26057 ,TRBC2 (E)DLRNVTPPKVSLFEPSKAEIAN..KQKATLVCLAR GFFP..DHVE LSWWVNGKEVHS..GVSTDPQAYKESN.....YSYCLSSRLRVSATFWH.NPRNHFRC QVQFHGLSEEDKWPEGSPKPVTQNI SAEAWGRA
M23381 ,TRDC (X)SQPPAKPSVFIMKNG...........TNVACLVK DFYP..KEVT ISLRSSKKI.....VEFDPAIVISPS......GKYSAVKLGQYGD.......SNSVTC SVQHN..............SETVHS TDFEPYANSF
M13340 ,TRGC1 (D)KRLDADISPKPTIFLPSVAETNL..HKTGTYLCLLE KFFP..DVIR VYWKEKDGNTIL..DSQEGDTLKTND.......TYMKFSWLTVPER....AMGKEHRC IVKHENN............KGGADQ EIFFPSIKK
M12834 ,TRGC2 (D)KRLDADISPKPTIFLPSVAETNL..HKTGTYLCLLE KFFP..DVIR VYWKEKNGNTIL..DSQEGDTLKTKG.......TYMKFSWLTVPER....AMGKEHSC IVKHENN............KGGADQ EIFFPSIKK
M12837 ,TRGC3 (D)KKLDADISPKPTIFLPSVAETNL..HKTGTYLCVLE KFFP..DVIR VYWKEKKGNTIL..DSQEGDMLKTND.......TYMKFSWLTVPER....SMGKEHRC IVKHENN............KGGADQ EIFFPTIKK
AF021335 ,TRGC4 (D)KRTDSDFSPKPTIFLPSAAETNL..HKAGTYLCLLE KFFP..EVIR VYWKEKDGEKIL..ESQEGNTIKTND.......RYMKFSWLTVTED....SMAKEHSC IVKHENN............KRGVDQ EILFPPIGK
CONNECTING-REGION
[EX2A] [EX2]
M64239 ,TRAC (D)VPCDATLTEKSFET
M26054 ,TRBC1 (D)CGITS
M26058 ,TRBC2 (D)CGITS
L36133 ,TRDC (N)NEKLPEPENDTQISEPCYGPR
M13341 ,TRGC1 (V)AVSTKPTTCWQDKN
M12835 ,TRGC2 (V)ATTCWQDKN
M12838 ,TRGC3 (V)AVSTKPTTCWQDKN
L02340 ,TRGC4 (A)FTTINVNPRDSVLRHEN (V)NNATDLEDCMKGRK [EX2B] (L02341)
TRANSMEMBRANE-REGION CYTOPLASMIC-REGION
[EX3] [EX4]
M64239 ,TRAC (D)MNLNFQNLSVMGLRILLLKVAGFNLLMTLRLWSS*
M26055 ,TRBC1 (A)SYQQGVLSATILYEILLGKATLYAVLVSTLVVMAM VKRKNS (M26056)
M26059 ,TRBC2 (A)SYHQGVLSATILYEILLGKATLYAVLVSGLVLMAM VKKKNS (M26060)
L36134 ,TRDC (V)TVHTEKVNMMSLTVLGLRLLFAKTIAINFLLTVKLFF*
M13342 ,TRGC1 (D)VLQLQFTITSAYYTYLLLLLKSVIYLAIISFSLLRRTSVCGNEKKS
M12836 ,TRGC2 (D)VLQFQFTSTSAYYTYLLLLLKSVIYLAIISFSLLRRTSVCGNEKKS
M12839 ,TRGC3 (D)VLQLQFTITSAYYTYLLLLLKSVIYLAIISFSLLRRTSVCCNEKKS
AF021335 ,TRGC4 (D)MLQLQVTTTYAFYTYLILFFKSMVHLAFVVFCLFRRAAMSCDDQRS
Created: Wednesday, 29-Jun-2011 17:06:04 CEST
Authors: Christelle Jean and Delphine Guiraudou
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
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