Only the *01 allele of each functional, ORF and in-frame pseudogene V-REGION is shown.
Dots indicate gaps according to the IMGT unique numbering. Blanks at the 5' and/or 3' end indicate partial sequences.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CH-S and in pages edited before 14/10/2009).
______________________________________________________________________________________________________________________________________________________ IGIV FR1-IMGT CDR1-IMGT FR2-IMGT CDR2-IMGT FR3-IMGT CDR3-IMGT genes (1-26) (27-38) (39-55) (56-65) (66-104) (105-115) ___________________________ __________________________ ____________ _________________ __________ _______________________________________ ____________ 1 10 20 30 40 50 60 70 80 90 100 110 .........|.........|...... ...|........ .|.........|..... ....|..... ....|.........|.........|.........|.... .....|..... #c AJ291769,IGIV1S1 QVTVTQPPV.KTSTPGSTVTISCKIN QVVYRDSDGDW. LHWYQQKSGQSPKLLIR YVS....... TRHSGTP.ARFSGSG..SRTDFTFTISGVQTEDAAVYYC QSYHSGGV #c AJ291771,IGIV1S2 QVTVTQPPV.KTFTPGSTVTISCKSN QAVVRDGDGDW. LHWYQQKSGQPPKLLIR YVS....... TRHSGTP.ARFSGSG..SRTDFTLTISGVQTEDAAVYYC QSVHSGPV #c AJ291770,IGIV1S3 QVTVTQPPV.KISTPGSTVTISCKTN QAVGSCGAGEC. MFWYQQKSGQSPKLLIR HVS....... IRHSGTP.ARFSGSG..SSSDFTFTISGVQTEDAAVYYC QSVHSGPV #c AJ291772,IGIV1S4 QVTVTQPPV.KISTPGSTVTISCKTN QAVGSCGAGEC. MFWYQQKSGQSPKLLVR HVS....... IRHSGTP.ARFSGSG..SSSDFTFTISGVQTEDAAVYYC QSVHSGPV #c AJ291776,IGIV1S5 QVTVTQPPV.KISTPGSTVTISCKTN QAVGSCGAGEC. MFWYQQKSGQSPKLLIR HVS....... IRHSGTP.ARFSGSG..SSSDFTFTISEVQTEDAAVYYC QSVHSGPV #c AJ291777,IGIV1S6 QVTVTQPPV.KISTPGSTVTISCKTN QAVGSCGAGEC. MFWYQQKSGQSPKLLIR HAS....... IRHSGTP.ARFSGSG..SSSDFTFTISGVQTEDAAVYYC QSVHTGPV #c AJ291780,IGIV1S7 QVTVTQPPV.KTSTPGSTVTISCKTN QAVGKCSGIDC. MFWYQQKSGQPPKLLIR HVS....... ISHSGTP.ARFSGSG..SSSDFTLTISGVQTEDAAVYYC ESVHNGPV #c AJ291768,IGIV1S8 QVTVTQPPV.KTFTPGSTITISCKIS EPVYICNGVDIC ISWYQQKSGQPPKLLIN HRS....... RRYSGTP.ARFSGSG..SSSDFTLTISGVQTEDAAVYYC QSVHSGGV #c AJ291774,IGIV1S9 QVTVTQPPV.KTFTPGSTVTISCKTN QAVYSHSLYGDY LHWYQQKSGQPPKLLIK LVS....... TRESGTP.ARFSGSG..SSSDFTLTISGVQTEDAAVYYC QSYHSGGV #c AJ291773,IGIV1S10 QVTVTQPPV.KTFTPGSTVTISCKTN QAVYRDSYYGDC MHWYQQKSGQPPKLLIT LVS....... TRESGTP.ARFSGSG..SSSDFILTISGVQTEDAAVYYC QSTHYINSAWV #c AJ400216,IGIV1S11 QLTVSQPAV.VTSSIEPTVTLTCQTN PKVKTWSDGTNR LHWYQQKSGQAPKLVMK NGK....... NPTSEFS.SRFSGRA..DGENSNLTISGVQTEDAAIYYC KRYDEINSAWV #c AJ400218,IGIV1S12 IEPTVTLTCQTN PKVKTWSDGTNR LHWYQQKSGQAPKLVMK NGK....... NPTSEFS.SRFSGRA..DGENSNLTISGVQTADAAIYYC KRYDEINSAWV #c AJ400220,IGIV1S13 IEPTVTLTCQTN PKVRTWSDGTNR LHWYQQKSGQAPKLVMK NGK....... NPTSEFS.SRFSGRA..DGENSNLTISGVQTEGAAIYYC KRYDEINSAWV #c AJ400223,IGIV1S14 IEPTVTLTCQTN PKVMTWSDGANR LHWYQQKSGQAPKLVMK NGK....... NPTSEFS.SRFSGRA..DGENSNLTISGVQTEDAAIYYC KRYDEINSAWV #c AJ400224,IGIV1S15 IEPTVTLTCQTN PKVKTWSDGTNR LHWYQQKSGQAPKLVMK NGK....... NPTSEFS.SRFSGRA..DGENSNLTISGVQTEDAAIYYC KRYDEINSAWV #c AJ400226,IGIV1S16 IEPTVTLTCQTN PKVKTWSDGTNR LHWYQQKSGQAPKLVMK NGK....... NPTSEFS.SRFPGRA..DGENSNLTISGVQTEDAAIYYC KRYDEINSAWV #c AJ400228,IGIV1S17 IEPTVTLTCQTN PKVKTWSDGTNR LHWYQQKSGQAPKLVMK NGK....... NPTSEFS.SRFSGRA..DGENSNLTISGVQTEDAAIYYC KRYDEINSAWV #c AJ400229,IGIV1S18 IEPTVTLTCQTN PKVKTWSDGPNR LHWYQQKSGQAPKLVMK NGK....... NPTSEFS.SRFSGRA..DGENSNLTISGVQTEDAAIYYC KRYDEINSAWV#c: rearranged cDNA
Created: 12/05/2003
Author: Nathalie Bosc
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
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