Only the *01 allele of each functional, ORF and in-frame pseudogene V-REGION is shown.
Dots indicate gaps according to the IMGT unique numbering. Blanks at the 5' and/or 3' end indicate partial sequences.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CH-S and in pages edited before 14/10/2009).
Two pseudogenes have been included (1).
______________________________________________________________________________________________________________________________________________________ IGIV FR1-IMGT CDR1-IMGT FR2-IMGT CDR2-IMGT FR3-IMGT CDR3-IMGT genes (1-26) (27-38) (39-55) (56-65) (66-104) (105-115) ___________________________ __________________________ ____________ _________________ __________ _______________________________________ ____________ 1 10 20 3032A 40 50 60 70 80 90 100 110 .........|.........|...... ...|......... .|.........|..... ....|..... ....|.........|.........|.........|.... .....|..... #c AB062646,IGIV1S1 QVTVTQPGA.VRSALGGSVTISCRTS QAVYNS.NY.... LAWYQQRDGEKPKLLIY YAS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHVINSQHV #c AB062628,IGIV1S2 QVTVTQSGA.VRSALGGSVTISCRTS QAVYNS.NY.... LAWYQQRDGEKPKLLIY YAS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHVINSQHV #c AB062649,IGIV1S3 QVTVTQSGA.VSSALGGSVTISCRSS QAVYNS.NY.... LAWYQQRDGEKPKLLIY YAS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHVINSQYV #c AB062651,IGIV1S4 QVTVTQPGA.VRSALGGSVTINCRTS QAVYNS.NY.... LAWYQQRDGEKPKLLIY YAS....... TRASGIP.GRFTGSG..SNSDFTLAISGVQTEDAAVYYC QSFHVINSQHV #c AB062656,IGIV1S5 QVTVTQSGA.VSSALGGSVTISCRTS QAVYNS.NY.... LAWYQQRDGEKPKLLIY YAS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHVINSQHV #c AB062662,IGIV1S6 QVTVTQSGA.VRSALGGSVTISCRTS QAVYNS.NY.... LAWYQQRDGEKPKLLIY YAS....... TRASGIP.GRFAGSG..SNSDFTLTISGVQTEDAAVYYC QSFHVINTQHV #c AB062665,IGIV1S7 QVTVTQSGA.VSSALGGSVTINCRTS QAVYNS.NY.... LHWYQQRDGEKPKLLIY DAS....... TRESGIP.GRFTGSG..SNSDFTLTISGVQTEDAGVYYC QSGHVINSLWV #c AB064322,IGIV1S8 QVTVTQSGA.VSSALGGSVTISCTTS QAVYNS.NY.... LAWYQQRDGEKPKLLIY RAT....... TRASGIP.GRFTRSG..SNSDFTLTISGVQTEDAAVYYC QSYHEINSQRV #c AB062666,IGIV1S9 QVTVTQSGA.VSSALGGSVTISCRTS QAVHSS.NR.... LAWYQQRDGEKPKLLIY YAS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSYHVINSQYV #c AB062622,IGIV1S10 QVTVTQSGA.MSSALGGSVTISCRTS QAVYGS.DR.... LAWYQQRDGEKPKLLIY YAS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAGVYYC QSGHVINSLWV #c AB062654,IGIV1S11 QVTVTQSGA.VSSALGGSGTISCRTS QAVYGS.DR.... LAWYQQRDGEKPKLLIY DAS....... TRESGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSLHYINSLWV #c AB062659,IGIV1S12 QVTVTQPGA.VSLALGGSVTISCRTS QAVYNS.DF.... LAWYQQRDGEKPKLLIY YAS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSAHYINSQLV #c AB062655,IGIV1S13 QVTVTQSGA.VSSALGGSVTMSCRTS QAVHNS.DF.... LNWYQQRDGEKPKLLIY YAS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHVT* #c AB062619,IGIV1S14 QVTVTQPGA.VSSALGGSVTISCRTS QAVYVS.SNKHR. LAWYQQRDGEKPKLLIY YAS....... TGASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHVINSQWV #c AB062635,IGIV1S15 QVTVTQSGA.VSSALGGSVTISCRTS QAVYVS.SNKHR. LAWYQQRDGEKPKLLIY YAS....... TGASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHVINSQWV #c AB062658,IGIV1S16 QVTVTQPGA.VSSALGGSVTISCRTS QAVYVS.SNKHR. LAWYQQRDGEKPKLLIY YAS....... TRASGIP.GRFTGSG..SNSDLTLTISGVQTEDAAVYSC QSFHSINSQLV #c AB062626,IGIV1S18 QVTVTQSGA.VSSALGGSVTISCRTS QAVYVS.RNKHR. LAWYQQRDGEKPKLLIY DAS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHVINSQEV #c AB062620,IGIV1S19 QVTVTQSGA.VSSALGGSVTISCRTS QAVYVS.RNKHR. LAWYQQRDGEKPKLLIY DAS....... TRASGIP.GRFTGSG..SNSEFTLTISGVQTEDAAVYYC QSFHVMNSQEV #c AB062642,IGIV1S20 QVTVTQSGA.VRSALGGSVTISCRTS QAVYVS.RNKHR. LAWYQQRDGEKPKLLIY DGS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHVINSQEV #c AB062648,IGIV1S22 QVTVTQPGA.VSLALGGSVTISCRTS QAVQVY.TNKHL. LAWYQQRDGEKPKLLIY YAS....... TRASGLP.GRFAGSG..SNSDFTLTISGVQAEDAAVYYC QSYHYINSQAV #c AB062668,IGIV1S23 QSRVTESGE.VNSALGGSVAIPYRSS QPVHLS.STKHP. LAWYQPPDAQIPNLLIY VST....... TRTSGIT.SRFTRSG..SHSDFTMTTSGVQTEYSPVCYC QSFHVVKS #c AB062664,IGIV1S24 QVTVRRCGQ.VGYVVGGSVPISCRTT QVVCVY.SNKHG. FAWSNKRVGEKPKLVFS GVS....... PGESGVQ.GRFQGGE..SNCALLLPVRGVKRKTEEVYIC KGFSVVNSKTV #c AB062623,IGIV1S25 QVTVTQPGA.VSSALGGSITIRCRVS QNVYTQ.GGHIP. FAWYRQRDGEPPKVLIY RAT....... TRVSGTP.SRFTGSG..SYSDFTLTISGVQTEDAGVYYC QSGHVINSLWV #c AB062627,IGIV1S26 QVTVTQSGA.VSSTVGRSVTISCMVS QNVYTQ.GGHIP. FAWYRQRDGEPPKVLIY RAT....... TRVSGTP.SRFTGSG..SNSDFTLTISGVQTEDAGVYYC QSGHVINSLWV #c AB062634,IGIV1S27 QVTVTQSGA.VRSAVGRSVTISCRVS QNVYTQ.GGHIP. FAWYRQTDGEPPKALIY RAN....... NRVSGTP.SRFTGSG..SYSDFTLTISGVQTEDAGVYYC QSGHVINSLWV #c AB062629,IGIV1S28 QVTVTQPGA.VSSALGRSVTISCRVS QNVYTQ.GGQIP. FAWYRQRDGEPPKALIY RAT....... TRLSGTP.SRFTGSG..SYSDFTLTISGVQTEDAGLYYC QSGHIINSLWV #c AB062641,IGIV1S29 QVTVTQPGA.VTSTLGRSVTIRCRVS QNVYTQ.GGHIP. FAWYRQRDGEAPKVLIY RAT....... TRISGTP.SRFTGSG..LYSDFTLTISGVQTEDAGVYYC QSGHVINSLWV #c AB062644,IGIV1S30 QVTLTQSGA.LSFARGRSVTIRCRVS QNVYTQ.GGHIP. FAWYRQRDGEPPKALIY RAT....... SRVSGTP.SRFTGSG..SYSDFTLTISGVQTEDAGVYYC QSGHVINSLWV #c AB062645,IGIV1S31 QVTVTQPGA.VNSGLGRSVTITCRVS QNVYTQ.GGHIP. FAWYRQRDGEPPKPLIY RAI....... TRVSGTP.SRFTGSG..LYSDFTMTISGVQTEDAGVYYC QSGHVINSLWV #c AB062660,IGIV1S32 QVTLTQSEA.LSFARGRSVTIRCRVS QNVYNQ.GSHIP. FAWYRQRDGEPPKALIY KAT....... SRVSGTP.SRFTGSG..SYSDFTLTISGVQTEDAGVYYC QSGHVINSLWV #c AB062661,IGIV1S33 QVTVTQPGA.VSSALGRSVTISCRVS QNVYTQ.GGHIP. FAWYRQRDGEPPKALIY RAT....... TRVSGTP.SRFTGSG..LYSDFTLTISGVQTEDAGVYYC QSGHVINSLWV #c AB062653,IGIV1S34 QVTVTQPGV.VNCVMGRSVTISCRVS QNVYTK.GGHIQ. FAWYREIYGELAKLFIY EAF....... TRVEGTP.SCFTGSG..SMSNFSLNISGVQTEDAGVYYC KSGNVINNLWV #c AB062624,IGIV1S35 QVTVTQSGA.VSSALGGSVTISCRTS QAVYTW.SSNHA. LAWYQQRDGETPKLLIY AAS....... TRVSGIP.GRFTGSG..SNSDFTLTISGVQTEDGAVYYC QSFHVINSQLV #c AB062630,IGIV1S36 QVTVTQSGA.VRSALGGSVTITCRTS QAVYTW.SSNHA. LAWYQQRDGETPKLLIY RAS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHYINSQHV #c AB062636,IGIV1S37 QVTVTQSGA.VSSALGGSVTISCRTS QAVYTW.SSNHA. LAWYQQRDGETPKLLIY DAS....... TRASGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHVINSQLV #c AB062637,IGIV1S38 QVTLTQSGA.VSSALGGSVTISCKTS QAVYTW.SSNHA. LAWYQQRDGEKTKLLIY YAS....... TQESGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHYINSQYV #c AB062621,IGIV1S39 QVTVTQSGA.VSSALGRSVTISCRVS RQVWSC.SSANC. LSWYQQKDGETPKLLIR YTN....... ERISGIP.GRFTGSG..SNTDFTLTISGVQAEDAGVYYC QSFHVINSQYV #c AB062638,IGIV1S40 QVTVTQSGA.VSSALGGSVTISCRTS QAVYYS.SPYHY. LAWYQQRDGEKPKLLIY LAT....... NRESGIP.GRFTGSG..SNSDFTLTISGVQTEDAAVYYC QSFHSINSQHV #c AB062647,IGIV1S41 NVVVTQSAA.KSVQVGQTVSVDCRAS PTVPHY.TGSQYY LSWYLQKPGEAPKLLIY RTS....... DRFSGIS.SRFSGNGAGNGVDFTLTISGVQAEDAGVYYC QSYHYINSQWV #c AB062650,IGIV1S42 QVTVTQPGA.VNSALGGSITISCRVS PKVFVGSSSGKHY LHWYQKRNGESPKLLIS RAD....... ERQSGIP.GRFTGSG..SNTDFTLTISGVQAEDSGVYYC QSYHEINSQYV#c: rearranged cDNA
IMGT note:
| (1) | IGIV1S13 | STOP-CODON at the end of CDR3-IMGT at codon 111 (positions 331-332 in IMGT unique numbering). |
| IGIV1S16 | STOP-CODON in L-REGION. |
Created: 05/05/2003
Author: Nathalie Bosc
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr |
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