Functionality is shown between parentheses, (F) and (P), when the accession number refers to a cDNA sequence and the corresponding genomic gene has not yet been isolated.
Click on a
gene name to get the alignment of the corresponding C-REGION alleles.
Click on an accession number to get the sequence and additional information (IMGT annotations, IMGT flat file, Coding regions...).
| IGHC gene name |
Exons | Fct | IGHC allele name |
Accession numbers | Confirmed by genetics and or data |
Description of mutations |
| IGHA1 | CH1 | F | IGHA1*01 | X53702 | + | |
| H | F | IGHA1*01 | X53702 | + | ||
| CH2 | F | IGHA1*01 | X53702 | + | ||
| CH3(including CH-S) | F | IGHA1*01 | X53702 | |||
| M | ||||||
| IGHA2 | CH1 | F | IGHA2*01 | X53706 | + | |
| H | F | IGHA2*01 | X53706 | + | ||
| CH2 | F | IGHA2*01 | X53706 | + | ||
| CH3(including CH-S) | F | IGHA2*01 | X53706 | |||
| M | ||||||
| IGHE | CH1 | F | IGHE*01 | M15398 | ||
| CH2 | F | IGHE*01 | M15398 | |||
| CH3 | F | IGHE*01 | M15398 | |||
| CH4(including CH-S) | F | IGHE*01 | M15398 | |||
| M1 | ||||||
| M2 | ||||||
| IGHG1 | CH1 | (F) | IGHG1*01 | X65284 | a252.2 |t315 | | |
| F | IGHG1*02 | AF300437 | a252.2>g|t315>c| | |||
| H | (F) | IGHG1*01 | X65285 | t27 | | ||
| F | IGHG1*02 | AF300437 | t27>c| | |||
| CH2 | (F) | IGHG1*01 | X61311 | g66 | | ||
| F | IGHG1*02 | AF300437 | g66>a| | |||
| CH3(including CH-S) | (F) | IGHG1*01 | X61310 | |||
| M1 | ||||||
| M2 | ||||||
| IGHG2 | CH1 | F | IGHG2*01 | AF300436 | ||
| H | F | IGHG2*01 | AF300436 | |||
| CH2 | F | IGHG2*01 | AF300436 | |||
| CH3(including CH-S) | ||||||
| M1 | ||||||
| M2 | ||||||
| IGHG3 | CH1 | F | IGHG3*01 | AF300434 | a268 ,T90 |t308 ,I103 |a318 |g319 ,D107 | | |
| IGHG3*02 | AF300435 | a268>g,T90>A|t308>c,I103>T|a318>g|g319>a,D107>N| | ||||
| H1 | F | IGHG3*01 | AF300434 | |||
| IGHG3*02 | AF300435 | |||||
| H2 | F | IGHG3*01 | AF300434 | t24 |c26 ,P9 | | ||
| IGHG3*02 | AF300435 | t24>c|c26>t,P9>L| | ||||
| CH2 | F | IGHG3*01 | AF300434 | t39 | | ||
| IGHG3*02 | AF300435 | t39>c| | ||||
| CH3(including CH-S) | ||||||
| M1 | ||||||
| M2 | ||||||
| IGHG4 | CH1 | F | IGHG4*01 | AF300432 | + | |
| H | F | IGHG4*01 | AF300432 | + | ||
| CH2 | F | IGHG4*01 | AF300432 | + | ||
| CH3(including CH-S) | ||||||
| M1 | ||||||
| M2 | ||||||
| IGHGP | CH1 | F | IGHGP*01 | AF300430 | ||
| IGHGP*02 | AF300431 | |||||
| H | F | IGHGP*01 | AF300430 | g49 ,A17 | | ||
| IGHGP*02 | AF300431 | g49>c,A17>P| | ||||
| CH2 | F | IGHGP*01 | AF300430 | t2.3 ,L1.3 |c4 ,P2 | | ||
| IGHGP*02 | AF300431 | t2.3>c,L1.3>P|c4>g,P2>A| | ||||
| CH3(including CH-S) | ||||||
| M1 | ||||||
| M2 |
Created: 12/11/2002
Author: Nathalie Bosc
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr |
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Citing IMGT © Copyright 1995-2012 IMGT®, the international ImMunoGeneTics information system® |
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