Table of alleles: Mouse (Mus musculus) TRBV

Print of this table: Bosc, N. and Lefranc, M.-P., Exp. Clin. Immunogenet., 17, 216-228 (2000). PMID:11096260

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.

The IMGT allele table refers to the V-REGION polymorphism. It does not include polymorphisms in the other parts of the V-GENE. V-REGION alleles are only described for genes which have at least one Functional or ORF allele. The accession number of a reference sequence is given for each allele.
Nucleotide mutations and amino acid changes in CDR3-IMGT of rearranged sequences are not taken into account for the description of polymorphism.

Click on a gene name to get the alignment of the corresponding V-REGION alleles.
Click on an accession number to get the sequence and additional information (IMGT annotations, IMGT flat file, Coding regions...).

TRBV
subgroup
TRBV
gene name
Fct
TRBV
allele name
Strain
Accession number
Confirmed
by genetics
and/or data
Descritpion of mutations
TRBV1
1
F
V1*01
BALB/c
AE000663
+
g178  ,G60  |g294  |
(F)
V1*02
BALB/c
X01642
  g178>a,G60>R|g294>a|
TRBV2
2
F
V2*01
BALB/c
AE000663
+
 
TRBV3
3
F
V3*01
BALB/c
AE000663
+
g176  ,G59  |
(F)
V3*02
B10.A
X03865
+
g176>t,G59>V|
TRBV4 4
F
 V4*01
C57BL/6
X56725 (1)
+
a32  ,H11  |a41  ,g42  ,Q14  |a70  ,K24  |t78  |g83  ,G28  |g88  ,D30  |t120  |c287  ,P96  |
(F)
 V4*02
SWR/J
AJ249819
  a32>g,H11>R|a41>g,g42>t,Q14>R|a70>g,K24>E|t78>c|g83>a,G28>D|g88>a,D30>N|t120>c|c287>t,P96>L|
TRBV5 5
F
V5*01
BALB/c
AE000663
+
c37  |g49  ,A17  |g70  ,E24  |a170  ,N57  |c172  ,L58  |g180  |a271  ,I91  |c287  ,P96  |
(F)
V5*02
BALB/c
X00438
+
c37>t|
(F)
V5*03
AKR
X02779
+
     |g49>a,A17>T|
(F)
V5*04
B10.S[9R]
M20878
 
c37>t|           |g70>c,E24>Q|
(F)
V5*05
SWR/J
AJ249820
 
                             |a170>g,N57>S|c172>g,L58>V|g180>a|a271>g,I91>V|c287>t,P96>L|
TRBV12
12-1
F
V12-1*01
C57BL/6
M15614
+
a41  ,E14  |
(F)
V12-1*02
NZW
M30881
 
a41>g,E14>G|
12-2
F
V12-2*01
C57BL/6
M15613
+
t71  ,I24  |
(F)
V12-2*02
BALB/c
X02782
 
t71>c,I24>T|
TRBV13
13-1
F
V13-1*01
C57BL/6
M15618
  g200  ,R67  |
F
V13-1*02
BALB/c
AE000663
+
g200>a,R67>Q|
13-2
F
V13-2*01
C57BL/6
M15617
+
g1  ,E1  |a29  ,N10  |a70  ,N24  |g147  |t165  |g179  ,G60  |t198  |g199  ,E67  |g206  ,G69  |a225  |g253  ,E85  |a256  ,c258  ,N86  |
(F)
V13-2*02
BALB/c nu/nu
M27350
 
                                                                   |g199>c,E67>Q|g206>c,G69>A|
(F)
V13-2*03
CBA/J
M26417
 
g1>a,E1>K|
(F)
V13-2*04
CI27
AJ249823
 
                     |a70>g,N24>D|
(F)
V13-2*05
ER34
AJ250103
 
         |a29>g,N10>S|a70>g,N24>D|g147>a|t165>c|g179>a,G60>D|t198>g|                         |a225>g|g253>a,E85>K|a256>g,c258>a,N86>E|
13-3
F
V13-3*01
C57BL/6
M15616
+
 
TRBV14
14
F
V14*01
BALB/c
AE000664
+
 
TRBV15
15
F
V15*01
BALB/c
AE000664
+
 
TRBV16
16
F
V16*01
C57BL/6
L29434
+
c74  ,P25  |a84  |t137  ,I46  |t155  ,F52  |c161  ,t162  ,T54  |
(F)
V16*02
C57BL/6
M13670
                                |t155>c,F52>S| 
(F)
V16*03
C57BL/6
M15459
 
c74>g,P25>R|a84>t|t137>g,I46>S|
(F)
V16*04
C57BL/6
X14388
 
                                           |c161>t,t162>c,T54>I|           
TRBV17
17 
F
V17*01
BALB/c
AE000664
+
 
TRBV19
19
F
V19*01
BALB/c
AE000664
+
t69  |a91  ,T31  |g298  ,A100  |
(F)
V19*02
C57BL/6
X01643
 
                              |g298>a,A100>T|
(F)
V19*03
SWR/J
AJ249821
 
t69>c|a91>t,T31>S|
TRBV20
20
F
V20*01
BALB/c
AE000664
+
t96  |a135  ,T49  |
(F)
V20*02
SJL
M11859
 
t96>c|a135>g,T49>A|
TRBV21
21
ORF
V21*01
BALB/c
X16691
+
 
TRBV23
23
F
V23*01
BALB/c
AE000664
+
 
TRBV24
24
F
V24*01
PWK
M61184
 
c66  |t90  |c152  ,T51  |g164  ,S55  |g257  ,c258  ,R86  |c306  ,Y102  |
P
V24*02
BALB/c
AE000664
 
c66>t|                  |g164>a,S55>N|g257>a,c258>g,R86>Q|c306>g,Y102>*| 
(ORF)
V24*03
BALB/c
M16203
+
c66>t|                  |g164>a,S55>N|g257>a,c258>g,R86>Q| 
(F)
V24*04
CzechII
L48997
 
c66>t|t90>c|c152>t,T51>I|g164>a,S55>N|
TRBV26
26
F
V26*01
B10.A
K02548
+
g91  ,V31 |c165  |
(F)
V26*02
SWR/J
AJ249822
 
g91>t,V31F|c165>t|
TRBV29
29
F
V29*01
BALB/c
AE000664
+
c22  ,P8  |
(F)
V29*02
BALB/c
X00696
 
c22>t,P8>S|
TRBV30
30
F
V30*01
BALB/c
X16695
+
 
TRBV31
31
F
V31*01
BALB/c
X03277
+
g50  ,S17  |
(F)
V31*02
B10.A
M26418
 
g50>a,S17>N| 

IMGT note:
(1)
The last codon of the CDR3-IMGT of the germline V-REGION is a STOP-CODON which may disappear during rearrangements.


Created: 26/10/1999
Last updated: Friday, 27-May-2016 21:03:38 CEST
Author: Nathalie Bosc

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