Reagents monoclonal antibodies: anti-human TRBV

This table lists reagents monoclonal antibodies, specific for the T cell Receptor Beta Variable regions (TRBV), which are commercially available.
Companies are encouraged to inform us of commercially available antibodies.

Only functional TRBV genes and alleles are listed.
The reactivities of the reagents monoclonal antibodies for different variable regions are shown between parentheses in the 'Clone name and Specificity' column.

% of peripheral CD3 positive cells in normal blood are from the Coulter, Serotec or BD Biosciences Web sites.


The reactivities as described in this table are not exhaustive. For more information on the products and their reactivity, please contact the companies. For antibodies quoted in the table: ThermoFisher Scientific (Pierce Endogen antibodies), Bio-rad (Serotec antibodies), Beckman Coulter (Coulter antibodies), and BD Biosciences

and
TRBV
gene name
 
TRBV
allele name
 
Reagents monoclonal antibodies
Clone name and Specificity Company product Isotype Combination of 24 antibodies in 8 vials for cytometry % of peripheral CD3 positive
cells in normal blood
TRBV2 TRBV2*01 IMMU 546   (TRBV2) Serotec V BETA 22
Coulter Vbeta22
Mouse IgG1
G_Vb22_IMMU546_PE+FITC

2.4-5.1
TRBV2*02
TRBV2*03
TRBV3-1 TRBV3-1*01 FIN9   (TRBV3-1)

AMKB1-2   (TRBV3-1)
Serotec Vbeta9
Coulter Vbeta9
Mouse IgG2a

Mouse IgG1

B_Vb9_FIN9_PE 1.6-3.2

0.5-3

TRBV3-1*02 BD Biosciences Vbeta9
TRBV4-1 TRBV4-1*01 ZOE   (TRBV4-1, TRBV4-2, TRBV4-3)

3G5   (TRBV4-1)

Serotec V BETA 7
Coulter Vbeta7
Mouse IgG2a A_Vb7.1_ZOE_PE+FITC
1.5-2.4
TRBV4-1*02 Pierce EndogenV beta 7.1 Mouse IgG2b

TRBV4-2 TRBV4-2*01 ZOE   (TRBV4-1, TRBV4-2, TRBV4-3) Serotec V BETA 7
Coulter Vbeta7
Mouse IgG2a A_Vb7.1_ZOE_PE+FITC
TRBV4-2*02
TRBV4-3 TRBV4-3*01 ZOE   (TRBV4-1, TRBV4-2, TRBV4-3) Serotec V BETA 7
Coulter Vbeta7
Mouse IgG2a A_Vb7.1_ZOE_PE+FITC
TRBV4-3*02
TRBV4-3*03
TRBV4-3*04 ZIZOU4 (TRBV4-3) Coulter Vbeta7.2 Mouse IgG2a H_Vb7.2_ZIZOU4_FITC
TRBV5-1 TRBV5-1*01 IMMU157   (TRBV5-1)


Serotec Vbeta5.1
Coulter Vbeta5.1
Mouse IgG2a C_Vb5.1_IMMU157_PE+FITC 4.8
4.2-7.2


0.5-3
TRBV5-1*02 LC4 (TRBV5-1) Pierce Endogen V beta 5(c)
BD Biosciences Vbeta5(c)
Mouse IgG1
TRBV5-4 TRBV5-4*01          
TRBV5-4*02
TRBV5-4*03
TRBV5-4*04
TRBV5-5 TRBV5-5*01
3D11   (TRBV5-5)


1C1   (TRBV5-5, TRBV5-6)



W112   (TRBV5-5)


MH3-2   (TRBV5-5, TRBV5-6)

Serotec VBETA5.3
Coulter Vbeta5.3
Mouse IgG1 A_Vb5.3_3D11_PE
1-1.8 (mean 1.4)



0.5-3



0.5-3

0.5-3
TRBV5-5*02 Pierce Endogen V beta 5(a)
BD Biosciences Vbeta5(a)
Mouse IgG1
TRBV5-5*03 Pierce Endogen V beta 5(b)
Serotec V beta 5.2/5.3
BD Biosciences Vbeta5(b)
Mouse IgG1
BD Biosciences Vbeta5 Mouse IgG2a
TRBV5-6 TRBV5-6*01 36213   (TRBV5-6)

1C1   (TRBV5-5, TRBV5-6)


MH3-2   (TRBV5-5, TRBV5-6)

Serotec Vbeta5.2
Mouse IgG1


Mouse IgG1


Mouse IgG2a
E_Vb5.2_36213_PE 0.5-1.5


0.5-1.5 (mean 0.8)
0.5-3

0.5-3
BD Biosciences Vbeta5(a)  
BD Biosciences Vbeta5  
TRBV5-8 TRBV5-8*01          
TRBV5-8*02
TRBV6-1 TRBV6-1*01 BAM13   (TRBV6-1, TRBV6-5) Pierce Endogen V beta 13
BD Biosciences Vbeta13.1, 13.3
Mouse IgG1 3-6
TRBV6-2 TRBV6-2*01 H132 Coulter Vbeta13.2 Mouse IgG1 H_Vb13.2_H132_PE
TRBV6-3 TRBV6-3*01          
TRBV6-4 TRBV6-4*01          
TRBV6-4*02
TRBV6-5 TRBV6-5*01 IMMU 222   (TRBV6-5, TRBV6-6 and TRBV6-9)


BAM13   (TRBV6-1, TRBV6-5)

Serotec V BETA 13.1
Coulter Vbeta13.1
Mouse IgG2b D_Vb13.1_IMMU222_PE
1.8-3.3
(JU74.3: 0.9-1.9)

3-6
Pierce Endogen V beta 13
BD Biosciences Vbeta13.1, 13.3
Mouse IgG1  
TRBV6-6 TRBV6-6*01 JU-74   (TRBV6-6)
JU74.3   (TRBV6-6)


IMMU 222   (TRBV6-5, TRBV6-6 and TRBV6-9)

Serotec Vbeta13.6
Coulter Vbeta13.6
Mouse IgG1 D_Vb13.6_JU74.3_PE+FITC
TRBV6-6*02
TRBV6-6*03
TRBV6-6*04 Serotec V BETA 13.1
Coulter Vbeta13.1
Mouse IgG2b D_Vb13.1_IMMU222_PE
TRBV6-6*05
TRBV6-8 TRBV6-8*01        
TRBV6-9 TRBV6-9*01 IMMU 222   (TRBV6-5, TRBV6-6 and TRBV6-9) Serotec V BETA 13.1
Coulter Vbeta13.1
Mouse IgG2b D_Vb13.1_IMMU222_PE
TRBV7-2 TRBV7-2*01 OT145   (TRBV7-2) Pierce Endogen V beta 6.7
BD Biosciences Vbeta6.7
Mouse IgG1  


0.5-3

TRBV7-2*02
TRBV7-2*03
TRBV7-2*04
TRBV7-3 TRBV7-3*01          
TRBV7-3*04
TRBV7-3*05
TRBV7-4 TRBV7-4*01          
TRBV7-6 TRBV7-6*01          
TRBV7-6*02
TRBV7-7 TRBV7-7*01         
TRBV7-7*02
TRBV7-8 TRBV7-8*01          
TRBV7-8*02
TRBV7-8*03
TRBV7-9 TRBV7-9*01          
TRBV7-9*02
TRBV7-9*03
TRVB7-9*04
TRBV7-9*05
TRBV7-9*06
TRBV7-9*07
TRBV9 TRBV9*01 BL37.2   (TRBV9) Serotec Vbeta1
Coulter Vbeta1
Rat IgG1 F_Vb1_BL37.2_PE+FITC 2.4 - 6.6
6
TRBV9*02
TRBV9*03
TRBV10-1 TRBV10-1*01 S511   (TRBV10-1, TRBV10-2, TRBV10-3) Pierce Endogen V beta 12
BD Biosciences Vbeta12
Mouse IgG2b  

0.5-3
TRBV10-1*02
TRBV10-2 TRBV10-2*01
TRBV10-2*02
TRBV10-3 TRBV10-3*01 VER2.32.1   (TRBV10-3)


S511   (TRBV10-1, TRBV10-2, TRBV10-3)

Serotec Vbeta12
Coulter Vbeta12
Mouse IgG2a E_Vb12_VER2.32_FITC 1.5
1.1-1.9



0.5-3
TRBV10-3*02
TRBV10-3*03 Pierce Endogen V beta 12
BD Biosciences Vbeta12
Mouse IgG2b  
TRBV10-3*04
TRBV11-1 TRBV11-1*01          
TRBV11-2 TRBV11-2*01 IG125   (TRBV11-2) Serotec Vbeta21.3
Coulter Vbeta21.3
Mouse IgG2a F_Vb21.3_IG125_FITC 2.2-3.6
TRBV11-2*02
TRBV11-2*03
TRBV11-3 TRBV11-3*01          
TRBV11-3*02
TRBV11-3*03
TRBV11-3*04
TRBV12-3 TRBV12-3*01 56C5   (TRBV12-3, TRBV12-4)


56C5.2   (TRBV12-3, TRBV12-4)


16G8   (TRBV12-3, TRBV12-4)

MX-6   (TRBV12-3, TRBV12-4)

JR2   (TRBV12-3, TRBV12-4, TRBV12-5)

Serotec Vbeta8.1/8.2
Coulter Vbeta8
Mouse IgG2a D_Vb8_56C5.2_FITC 4.2
2.6-5.1


0.5-3


0.5-3



TRBV12-4 TRBV12-4*01 Pierce Endogen V beta 8(a)
BD Biosciences Vbeta8
Mouse IgG2b  
TRBV12-4*02 Pierce Endogen V beta 8(b) Mouse IgG2a  
BD Biosciences Vbeta8 Mouse IgG2b  
TRBV12-5 TRBV12-5*01 JR2   (TRBV12-3, TRBV12-4, TRBV12-5) BD Biosciences Vbeta8 Mouse IgG2b   0.5-3
TRBV13 TRBV13*01 AF-23   (TRBV13)
AF23   (TRBV13)
AHUT7   (Vbeta23)
Serotec Vbeta23
Coulter Vbeta23
BD Biosciences Vbeta23
Mouse IgG1 F_Vb23_AF23_PE
0.4-5
0.5-3
TRBV13*02  
TRBV14 TRBV14*01 TAMAYA1.2   (TRBV14) Serotec Vbeta16
Coulter Vbeta16
Mouse IgG1 B_Vb16_TAMAYA1.2_FITC 0.8
0.4-1.1
TRBV14*02
TRBV15 TRBV15*01          
TRBV15*02
TRBV15*03
TRBV16 TRBV16*01          
TRBV16*03
TRBV18 TRBV18*01 BA62   (TRBV18)
BA62.6   (TRBV18)
Serotec V BETA 18
Coulter Vbeta18
Mouse IgG1 C_Vb18_BA62.6_PE 0.7-2.2
0.7-1.4
TRBV19 TRBV19*01
C1   (TRBV19)

E17.5F3   (TRBV19)
E17.5F3.15.13   (TRBV19)

Pierce Endogen V beta 17
BD Biosciences Vbeta17
Mouse IgG1  

0.5-3

3.3-7

TRBV19*02
Serotec Vbeta17
Coulter Vbeta17
Mouse IgG1 B_Vb17_E17.5F3_PE+FITC
TRBV19*03
TRBV20-1 TRBV20-1*01 MPB2D5   (TRBV20-1) Serotec VBETA2
Coulter Vbeta2
Mouse IgG1 E_Vb2_MPB2D5_PE+FITC 4.2-9.1
10
TRBV20-1*02
TRBV20-1*03
TRBV20-1*04
TRBV20-1*05
TRBV20-1*06
TRBV20-1*07
TRBV24-1 TRBV24-1*01          
TRBV25-1 TRBV25-1*01 C21   (TRBV25-1) Serotec V BETA 11
Coulter Vbeta11
Mouse IgG2a G_Vb11_C21_PE 0.8
0.4-0.9
TRBV27 TRBV27*01 CAS1.1.3   (TRBV27) Serotec Vbeta14
Coulter Vbeta14
Mouse IgG1 G_Vb14_CAS1.1.3_FITC 2.2-5.6
TRBV28 TRBV28*01 CH92   (TRBV28)


8F10   (TRBV28)

JOVI-3   (TRBV28)

Serotec Vbeta3
Coulter Vbeta3
Mouse IgM A_Vb3_CH92_FITC 2.9
2.2-5.6


3
Pierce Endogen V beta 3.1

BD Biosciences Vbeta3
Mouse IgG1

Mouse IgG2a
 
TRBV29-1 TRBV29-1*01 WJF24 Coulter Vbeta4 Rat IgM H_Vb4_WJF24_PE+FITC  
TRBV29-1*02
TRBV29-1*03
TRBV30 TRBV30*01 ELL1.4   (TRBV30) Serotec Vbeta20
Coulter Vbeta20
Mouse IgG1 C_Vb20_ELL1.4_FITC 2.2
TRBV30*02
TRBV30*04
TRBV30*05


Created: 24/06/2003
Last updated: 13/03/2019
Authors: Géraldine Folch, Joumana Jabado-Michaloud and Marie-Paule Lefranc.

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