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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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Truncated pseudogenes not assigned to subgroups with functional genes

Pseudogenes which could not be assigned to subgroups with functional genes are designated by a roman number between parentheses, corresponding to the clans, followed by a S and a number for the localization from 3' to 5' in the locus.

IMGT gene name IMGT allele name Fct Chromosomal localization R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Clone names Accession numbers Positions in the sequence (V-REGION) Secondary accession numbers Clone names Accession numbers Positions in the sequence (V-REGION)
IGHV(I)S1 IGHV(I)S1*01 P (1) 7q BK009030 [1] 143-436 (12)
IGHV(I)S2 IGHV(I)S2*01 P (2) BK008946 [1] 141-436
IGHV(I)S3 IGHV(I)S3*01 P (1) BK008972 [1] 143-439 (12)
IGHV(I)S4 IGHV(I)S4*01 P (2) BK008912 [1] 128-423 (13)
IGHV(II)S1 IGHV(II)S1*01 P (3) 7q BK009011 [1] 1-276 (14)
IGHV(II)S2 IGHV(II)S2*01 P (1) 7q BK009017 [1] 15-311
IGHV(II)S3 IGHV(II)S3*01 P (1) 7q BK009025 [1] 15-311
IGHV(II)S4 IGHV(II)S4*01 P (3) 7q BK009032 [1] 1-291 (14)
IGHV(II)S5 IGHV(II)S5*01 P (2) 7q BK009038 [1] 14-303 (15)
IGHV(II)S6 IGHV(II)S6*01 P (4) 7q BK009042 [1] 14-314 (13)
IGHV(II)S7 IGHV(II)S7*01 P (5) 7q BK009045 [1] 12-308
IGHV(II)S8 IGHV(II)S8*01 P (2) 7q BK009053 [1] 1-274 (14)
IGHV(II)S9 IGHV(II)S9*01 P (6) 7q BK009056 [1] 1-183 (14)
IGHV(II)S10 IGHV(II)S10*01 P (2) BK008943 [1] 1-282 (14)
IGHV(II)S11 IGHV(II)S11*01 P (1) BK008979 [1] 12-313
IGHV(II)S12 IGHV(II)S12*01 P (1) BK008982 [1] 1-258 (14)
IGHV(II)S13 IGHV(II)S13*01 P (1) BK008988 [1] 1-270 (14)
IGHV(II)S14 IGHV(II)S14*01 P (7) BK008999 [1] 17-312
IGHV(II)S15 IGHV(II)S15*01 P (8) BK009001 [1] 1-291 (14)
IGHV(II)S17 IGHV(II)S17*01 P (9) 7q BK009059 [1] 12-247 (16)
IGHV(III)S1 IGHV(III)S1*01 P (10) 7q BK009007 [1] 115-409
IGHV(III)S2 IGHV(III)S2*01 P (1) 7q BK009013 [1] 1-306 (13)
IGHV(III)S3 IGHV(III)S3*01 P (10) 7q BK009021 [1] 18-311
IGHV(III)S4 IGHV(III)S4*01 P (8) 7q BK009023 [1] 115-408
IGHV(III)S5 IGHV(III)S5*01 P (6) BK008947 [1] 107-375 (15)
IGHV(III)S6 IGHV(III)S6*01 P (2) BK008953 [1] 115-407 (15)
IGHV(III)S7 IGHV(III)S7*01 P (2) BK008957 [1] 103-407
IGHV(III)S8 IGHV(III)S8*01 P (1) BK008973 [1] 121-378 (16)
IGHV(III)S9 IGHV(III)S9*01 P (1) BK008991 [1] 1-307
IGHV(III)S10 IGHV(III)S10*01 P (2) 7q BK009058 [1] 32-326 (15)
IGHV(III)S11 IGHV(III)S11*01 P (11) BK008913 [1] 107-290 (17)
IGHV(III)S12 IGHV(III)S12*01 P (2) BK008960 [1] 115-404
IGHV(III)S13 IGHV(III)S13*01 P (1) BK008983 [1] 100-395
IMGT notes:
  1. (1) frameshifts in V-REGION, not assigned to subgroups with functional genes
  2. (2) frameshifts in V-REGION
  3. (3) frameshift in FR2-IMGT, not assigned to subgroups with functional genes
  4. (4) frameshifts in V-REGION, no L-PART1, no L-PART2, no V-RS
  5. (5) frameshift in V-REGION
  6. (6) truncated pseudogenes not assigned to subgroups with functional genes
  7. (7) STOP-CODON and frameshifts in V-REGION, not assigned to subgroups with functional genes, noncanonical ACCEPTOR-SPLICE
  8. (8) frameshift in V-REGION, not assigned to subgroups with functional genes
  9. (9) frameshift in FR1-IMGT
  10. (10) frameshifts in V-REGION, not assigned to subgroups with functional genes, noncanonical ACCEPTOR-SPLICE
  11. (11) frameshift in V-REGION, no L-PART1, no L-PART2
  12. (12) no V-RS
  13. (13) putative limit in 3' of V-REGION
  14. (14) partial in 5'
  15. (15) putative limit in 5' and 3' of V-REGION
  16. (16) partial in 3'
  17. (17) partial in 3', putative limit in 5' of V-REGION
IMGT references:
  1. [1] Yu et al., Immunogenetics, 68(6-7), 417-428(2016). PMID: 27233955
See also (IMGT Scientific chart):