Here you are: IMGT Web resources > IMGT Repertoire (IG and TR) > 1. Locus and genes

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT subgroup IMGT gene name IMGT allele name Fct Chromosomal
localization
R T Pr IMGT/LIGM-DB locus reference sequences IMGT/LIGM-DB sequences from the literature
Breed Clone names Accession numbers Positions in the sequence
(D-GENE-UNIT)
Secondary accession numbers Breed Clone names Accession numbers Positions in the sequence
(D-GENE-UNIT)
IGHD1 IGHD1-1 IGHD1-1*01 F 21q24 Holstein KT723008 [1] 284856-284942 Hereford BosTau_1_chr21 complement(125560-125646)
IGHD1-2 IGHD1-2*01 ORF (1) 21q24 Holstein KT723008 [1] 369474-369560
IGHD1-3 IGHD1-3*01 ORF (2) 21q24 Holstein KT723008 [1] 422613-422787
IGHD1-4 IGHD1-4*01 F 21q24 Holstein KT723008 [1] 476206-476292
IGHD2 IGHD2-1 IGHD2-1*01 F 21q24 Holstein KT723008 [1] 286100-286171 Hereford BosTau_1_chr21 complement(124331-124402)
IGHD2-2 IGHD2-2*01 F 21q24 Holstein KT723008 [1] 370692-370763
IGHD2-3 IGHD2-3*01 F 21q24 Holstein KT723008 [1] 423840-423911
IGHD2-4 IGHD2-4*01 F 21q24 Holstein KT723008 [1] 477433-477504
IGHD3 IGHD3-1 IGHD3-1*01 F 21q24 Holstein KT723008 [1] 287243-287334 Hereford BosTau_1_chr21 complement(123179-123270)
Holstein HM543732 [3] (5) 2-93
HM543737 [3] (5) 2-93
IGHD3-3 IGHD3-3*01 F 21q24 Holstein KT723008 [1] 424980-425071 Holstein HM543732 [3] (6) 2-93
HM543737 [3] (6) 2-93
IGHD3-4 IGHD3-4*01 F 21q24 Holstein KT723008 [1] 478574-478665 Holstein HM543732 [3] (7) 2-93
HM543737 [3] (7) 2-93
IGHD4 IGHD4-1 IGHD4-1*01 F 21q24 Holstein KT723008 [1] 287686-287784 Hereford BosTau_1_chr21 complement(122729-122827)
Holstein HM543736 [3] 2-100
IGHD5 IGHD5-2 IGHD5-2*01 F 21q24 Holstein KT723008 [1] 371829-371926 AY559838 [4] 2-99
IGHD5-3 IGHD5-3*01 F 21q24 Holstein KT723008 [1] 425887-425984 Holstein HM543734 [3] (8) 2-99
IGHD5-4 IGHD5-4*01 F 21q24 Holstein KT723008 [1] 479486-479583 Holstein HM543734 [3] (9) 2-99
IGHD6 IGHD6-2 IGHD6-2*01 F 21q24 Holstein KT723008 [1] 372840-372953 AY559840 [4] 2-115
IGHD6-3 IGHD6-3*01 F 21q24 Holstein KT723008 [1] 426339-426452 Holstein HM543735 [3] (10) 2-115
IGHD6-4 IGHD6-4*01 F 21q24 Holstein KT723008 [1] 479938-480051 Holstein HM543735 [3] (11) 2-115
IGHD7 IGHD7-3 IGHD7-3*01 F 21q24 Holstein KT723008 [1] 425411-425533 Holstein HM543733 [3] 2-124
IGHD7-4 IGHD7-4*01 F 21q24 Holstein KT723008 [1] 479005-479133
IGHD8 IGHD8-2 IGHD8-2*01 F 21q24 Holstein KT723008 [1] 372282-372485 AY559839 [4] 2-205
IGHD9 IGHD9-1 IGHD9-1*01 F 21q24 Holstein KT723008 [1] 319619-319688 Hereford NW_001494075 complement(40319-40388)
IGHD9-1*02 ORF (3) 21q24 AY149283 [2] (4) 85-154
IGHD9-4 IGHD9-4*01 F 21q24 Holstein KT723008 [1] 504099-504168
IMGT notes:
  1. (1) noncanonical 5'D-HEPTAMER: caccctg instead of cactgtg
  2. (2) noncanonical 3'D-HEPTAMER: caaggtg instead of cacagtg, noncanonical 3'D-NONAMER: actcgggac instead of acaaaaacc
  3. (3) noncanonical 3'D-HEPTAMER: cacaaaa instead of cacagtg
  4. (4) Sequence not in locus
  5. (5) Can also be assigned to IGHD3-3*01 or IGHD3-4*01
  6. (6) Can also be assigned to IGHD3-1*01 or IGHD3-4*01
  7. (7) Can also be assigned to IGHD3-1*01 or IGHD3-3*01
  8. (8) Can also be assigned to IGHD5-4*01
  9. (9) Can also be assigned to IGHD5-3*01
  10. (10) Can also be assigned to IGHD6-4*01
  11. (11) Can also be assigned to IGHD6-3*01
IMGT references:
  1. [1] Ma L. et al. J Immunol. 2016 May 15;196(10):4358-66. doi: 10.4049/jimmunol.1600158. Epub 2016 Apr 6. PMID: 27053761
  2. [2] Hosseini A. et al. Int Immunol. 2004 Jun;16(6):843-52. Epub 2004 May 4. PMID: 15126417
  3. [3] Koti M. et al. Mol Immunol. 2010 Jul;47(11-12):2119-28. doi: 10.1016/j.molimm.2010.02.014. PMID: 20435350
  4. [4] Shojaei F. et al. Mol Immunol. 2003 Sep;40(1):61-7. PMID: 12909131
See also (IMGT Scientific chart):