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Citing this page:
Lefranc, M.-P. et al., Eur. J. Immunol., 19, 989-994 (1989) PMID: 2526744
Lefranc, M.-P. and Lefranc, G., The T cell receptor FactsBook, Academic Press, London, 398 pages (2001)

Human (Homo sapiens) TRG locus on chromosome 7 (7p14)

The orientation of the human (Homo sapiens) TRG locus on the chromosome 7 (7p14) is reverse (REV).

Locus representation human TRG

Legend:
Colors are according to IMGT color menu for genes.
The boxes representing the genes are not to scale. Exons are not shown.

Double arrows indicate insertion/deletion polymorphisms.

Locus representation with only the functional genes: Human (Homo sapiens) TRG

Gene localization is according to data from IMGT/LocusView.
This locus representation with only the functional genes is used with IMGT/GeneFrequency.

Locus representation human TRG

* When needed, indicate the presence of allele(s) with another functionality: see above Human (Homo sapiens) TRG locus

Zoom for TRGJ genes

zoom

IMGT references:
  1. [1] Lefranc, M.-P. and Lefranc, G., The T cell receptor FactsBook, Academic Press, London, 398 pages (2001).
  2. [2] Lefranc, M.-P., Nomenclature of the human T cell receptor genes, Current Protocols in Immunology, A.1O.1-A.1O.23 (2000).
  3. [3] Lefranc, M.-P. and Rabbitts, T.H., TIBS, 14, 214-218 (1989). PMID: 2527426
  4. [4] Lefranc, M.-P. et al., Eur. J. Immunol., 19, 989-994 (1989). PMID: 2526744
  5. [5] Lefranc, M.-P. and Rabbitts, T.H., Res. Immunol., 141, 565-577 (1990). PMID: 2151348
  6. [6] Lefranc, M.-P. and Rabbitts, T.H., Res. Immunol., 141, 615-618 (1990). PMID: 1965674
TRGV genes
  1. [7] Lefranc, M.-P. et al., Cell, 45, 237-246 (1986). PMID: 2938743
  2. [8] Forster, A. et al., EMBO J., 6, 1945-1950 (1987). PMID: 2820713
  3. [9] Huck, S. et al., EMBO J., 7, 719-726 (1988). PMID: 2969332
  4. [10] Zhang, X.M. et al., Eur. J. Immunol., 24, 571-578 (1994). PMID: 8125127
  5. [11] Zhang, X.M. et al., Immunogenetics, 43, 196-203 (1996). PMID: 8575818
TRGJ genes
  1. [12] Huck, S. and Lefranc, M.-P., FEBS Lett., 224, 291-296 (1987). PMID: 2961609
TRGC genes
  1. [13] Lefranc, M.-P. et al., Proc. Natl. Acad. Sci., 83, 9596-9600 (1986). PMID: 2879283
  2. [14] Buresi, C. et al., Immunogenetics, 29, 161-172 (1989). PMID: 2564370
Silencers and enhancer
  1. [15] Lefranc, M.-P. and Alexandre, D., Eur. J. Immunol., 25, 617-622 (1995). PMID: 7875223
RFLP polymorphisms of the TRGV and TRGC genes
  1. [16] Buresi, C. et al., Immunogenetics, 29, 161-172 (1989). PMID: 2564370
  2. [17] Ghanem, N. et al., Immunogenetics, 30, 350-360 (1989). PMID: 2572547
  3. [18] Ghanem, N. et al., Human Genet., 86, 450-456 (1991). PMID: 1673112