Here you are: IMGT Web resources > IMGT Repertoire (IG and TR) >

This table lists reagents monoclonal antibodies, specific for the T cell Receptor Alpha Variable (TRAV) regions, which are commercially available.
The reactivities of the reagents monoclonal antibodies for different variable regions are shown between parentheses in the 'Clone name and Specificity' column.
The reactivities as described in this table are not exhaustive. For more information on the products and their reactivity, please contact the companies: BD BioSciences Pharmingen, CEDARLANE laboratories Ltd.

Owing to the duplication of TRAV genes in the mouse TRA locus, the assignment of reagent monoclonal antibodies is only possible at the subgroup level.

TRAV haplotypes are shown with a superscript letter:

TRAV subgroup Reagents monoclonal antibodies
Clone name and Specificity Company product Species and Isotype Strain host Immunogen
TRAV1
TRAV2
TRAV3
TRAV4 RR8-1(TRAV4) BD Pharmingen Vα11.1/Vα11.2b,d Rat IgG2b,κ Mouse T cell clone B10
TRAV5
TRAV6
TRAV7
TRAV8
TRAV9 RR3-16(TRAV9) BD Pharmingen Vα3.2b,c Rat IgG2b,κ Fischer Mouse cytotoxic T cell clone OH6
TRAV10
TRAV11
TRAV12 KT50(TRAV12) BD Pharmingen Vα8.3a,b,c,d Rat IgG2a,κ Sprague-Dawley (SD) Mouse T cell clone C6
B21.14(TRAV12) BD Pharmingen Vα8.3a,b,c,d Rat IgG1,κ LOU/W1 Soluble TR αβ from mouse cytotoxic T cell clone CW3/1.1
CTVA8(TRAV12) CEDARLANE Vα8 Rat IgG2a
TRAV13
TRAV14 B20.1(TRAV14) BD Pharmingen Vα2a,b,c Rat IgG2a,λ LOU/W1 Soluble TR αβ from mouse cytotoxic T cell clone KB5-C20
B20.1(TRAV14) CEDARLANE Vα2 Rat IgG2a
TRAV15
TRAV16
TRAV17
TRAV18
TRAV19
TRAV20
TRAV21
TRAV22
TRAV23
Anti-idiotypic mab reagent KJ1-26 (antiodiotypic for the TR αβ of Do11.10) (1) CEDARLANE Mouse IgG2a Mouse T cell hybridoma D011.10
IMGT notes:
  1. (1) Binds the TR expressed on DO11.10 and DO11.10.24 murine T cell hybridomas. The TR expressed on DO11.10 recognizes an ovalbumin peptide in the context of I-Ad (MH2-AAd) [1,2]
IMGT references:
Created:
04/10/2010
Last updated:
29/06/2011
Authors:
Géraldine Folch
Editor:
Chantal Ginestoux