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This table lists reagents monoclonal antibodies, specific for the T cell Receptor Beta Variable (TRBV) regions, which are commercially available. The reactivities of the reagents monoclonal antibodies for different variable regions are shown between parentheses in the 'Clone name and Specificity' column. The reactivities as described in this table are not exhaustive. For more information on the products and their reactivity, please contact the companies: BD BioSciences Pharmingen, CEDARLANE laboratories Ltd.

Only functional TRBV genes are listed.

IMGT subgroup IMGT gene name Reagents monoclonal antibodies
Clone name and Specificity Company product Species and Isotype Strain host Immunogen
TRBV1 TRBV1 B20.6(TRBV1) BD Pharmingen Vβ2 Rat IgG2a,κ LOU/W1 Mouse cytotoxic T cell clone CW3/1.1
TRBV2 TRBV2 KT4(TRBV2) BD Pharmingen Vβ4 Rat IgG2b,κ Sprague-Dawley B10.D2 mouse T cell clone I3
TRBV2 CTVB4(TRBV2) CEDARLANE Vβ4 Rat IgG2a
TRBV3 TRBV3
TRBV4 TRBV4 B21.5(TRBV4) BD Pharmingen Vβ10 Rat IgG2a,λ LOU/W1 Soluble TR αβ from mouse cytotoxic T cell clone
TRBV4 CTVB10b(TRBV4) CEDARLANE Vβ10 Rat IgG2b
TRBV5 TRBV5
TRBV6 TRBV6
TRBV7 TRBV7
TRBV8 TRBV8
TRBV9 TRBV9
TRBV10 TRBV10
TRBV11 TRBV11
TRBV12 TRBV12-1 MR9-4(TRBV12-1, TRBV12-2) BD Pharmingen Vβ5.1/5.2 Mouse IgG1,κ SWR Mouse T cell hybridoma 2HB51.8
TRBV12-2 MR9-4(TRBV12-1, TRBV12-2) BD Pharmingen Vβ5.1/5.2 Mouse IgG1,κ SWR Mouse T cell hybridoma 2HB51.8
TRBV12-3
TRBV13 TRBV13-1 F23.1(TRBV13-1,TRBV13-2,TRBV13-3) BD Pharmingen Vβ8.1/8.2/8.3 Mouse IgG2a,κ C57L/J BALB.B mouse lymph node and spleen T cells
TRBV13-1 1B3.3(TRBV13-1) BD Pharmingen Vβ8.3 Armenian hamster IgG3,λ1 Mouse Th1 clone 3.L2
TRBV13-1 CT-8C1, CT8C1, KT-8C1(TRBV13-1) CEDARLANE Vβ8.3 Mouse IgG2a
TRBV13-1 CT-8E, CT8E, KT-8E(TRBV13-1,TRBV13-2) CEDARLANE Vβ8.2/8.3 Mouse IgG2a
TRBV13-2 F23.1(TRBV13-1,TRBV13-2,TRBV13-3) BD Pharmingen Vβ8.1/8.2/8.3 Mouse IgG2a,κ C57L/J BALB.B mouse lymph node and spleen T cells
TRBV13-2 MR5-2(TRBV13-2, TRBV13-3) BD Pharmingen Vβ8.1/8.2 Mouse IgG2a,κ C57L C57BL/6 mouse helper T cell clone OI6
TRBV13-2 KJ16(TRBV13-2, TRBV13-3) CEDARLANE Vβ8.1/8.2 Rat IgG1
TRBV13-2 CT-8E(TRBV13-1,TRBV13-2) CEDARLANE Vβ8.2/8.3 Mouse IgG2a
TRBV13-3 F23.1(TRBV13-1,TRBV13-2,TRBV13-3) Pharmingen Vβ8.1/8.2/8.3 Mouse IgG2a,κ C57L/J BALB.B mouse lymph node and spleen T cells
TRBV13-3 MR5-2(TRBV13-2, TRBV13-3) BD Pharmingen Vβ8.1/8.2 Mouse IgG2a,κ C57L C57BL/6 mouse helper T cell clone OI6
TRBV13-3 KJ16(TRBV13-2, TRBV13-3) CEDARLANE Vβ8.1/8.2 Rat IgG1
TRBV14 TRBV14 MR12-3(TRBV14) BD Pharmingen Vβ13 Mouse IgG1,κ C57BR
TRBV15 TRBV15 MR11-1(TRBV15) BD Pharmingen Vβ12 Mouse IgG1,κ
TRBV15 CTVB12b(TRBV15) CEDARLANE Vβ12b Rat IgG2a
TRBV16 TRBV16 RR3-15(TRBV16) BD Pharmingen Vβ11 Rat IgG2b,κ Mouse cytolytic T cell clone OH6
TRBV16 CTVB11(TRBV16) CEDARLANE Vβ11 Rat IgG2b
TRBV17 TRBV17 MR10-2(TRBV17) BD Pharmingen Vβ9 Mouse IgG1,κ Mouse T cell hybridoma 2BR18
TRBV18 TRBV18
TRBV19 TRBV19 RR4-7(TRBV19) BD Pharmingen Vβ6 Rat IgG2b,λ C57BL/6 mouse helper T cell clone OI1
TRBV20 TRBV20
TRBV21 TRBV21
TRBV22 TRBV22
TRBV23 TRBV23
TRBV24 TRBV24 KJ23(TRBV24) BD Pharmingen Vβ17 Mouse IgG2a,κ BALB/c SWR Mouse T cells
TRBV25 TRBV25
TRBV26 TRBV26 KJ25(TRBV26) BD Pharmingen Vβ3 Armenian hamster IgG2,κ TR αβ purified from mouse T cell hybridoma 2B4.6
TRBV27 TRBV27
TRBV28 TRBV28
TRBV29 TRBV29 TR310(TRBV29) BD Pharmingen Vβ7 Rat IgG2b,κ Fischer AKR/Cum mouse spontaneous T lymphoma cell line TK1
TRBV29 TR310(TRBV29) CEDARLANE Vβ7 Rat IgG2b,κ
TRBV30 TRBV30
TRBV31 TRBV31 14-2(TRBV31) BD Pharmingen Vβ14 Rat IgM,κ B10.A mouse helper T cell clone J9.19
Created:
04/10/2010
Last updated:
29/06/2011
Authors:
Géraldine Folch
Editor:
Chantal Ginestoux