Here you are: IMGT Web resources > IMGT Repertoire (RPI) > RPI entries from gene to protein
Other B7 Family entries

IMGT RPI entry from gene to protein for Homo sapiens B7A1

Citing IMGT RPI entry for B7A1

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

B7A1 Gene exon/intron organization

Legend:

Number of alleles: 2

IMGT reference alleles

Allele names Gene functionality Clone names IMGT reference sequences
Exons Accession numbers Molecule type
B7A1*01 F EX1 M83072 gDNA splicing A
EX2 M83073
EX3 M83074
EX4 M83075
EX5 M83077
B7A1*02 F EX1-2 AY081815 cDNA (2) splicing C

IMGT reference sequences (in FASTA format) for the allele(s): B7A1*01 to B7A1*02

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
B7A1*01 F EX1-EX5 M27533 cDNA
BC042665 cDNA
EX1-5 NM_005191 cDNA
EX1-EX3, EX5 AY197778 cDNA (1) splicing B
AY197777 cDNA

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
B7A1*01 M83072 P33681 288 aa 1
M83073 288 aa 1
M83074 288 aa 1
M83075 288 aa 1
M83077 288 aa 1
NM_005191 NP_005182 288 aa 1
B7A1*02 AY081815 148 aa 3
IMGT notes:
  1. (1) Splicing B (251 aa). No EX4. New amino acid (T1>S) at position 1 due to alternative splicing in EX5.
  2. (2) Splicing C (148 aa). No EX3-5. EX2 has has no DONOR-SPLICE site and the transcript ends after 9 codons beyond the usual 3' splice site and a326>c; Y109>S, positions according to IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN.
IMGT references:
  1. [1] Selvakumar.A, et al. Immunogenetics 36, 175-181 (1992). PMID: 1377173

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

B7A1*01: M83072(g) M83073(g) M83074(g) M83075(g) M83077(g)

Nucleotide sequence

1        atgggccaca cacggaggca gggaacatca ccatccaagt gtccatacct caatttcttt

61       cagctcttgg tgctggctgg tctttctcac ttctgttcag gtgttatcca cgtgaccaag

121      gaagtgaaag aagtggcaac gctgtcctgt ggtcacaatg tttctgttga agagctggca

181      caaactcgca tctactggca aaaggagaag aaaatggtgc tgactatgat gtctggggac

241      atgaatatat ggcccgagta caagaaccgg accatctttg atatcactaa taacctctcc

301      attgtgatcc tggctctgcg cccatctgac gagggcacat acgagtgtgt tgttctgaag

361      tatgaaaaag acgctttcaa gcgggaacac ctggctgaag tgacgttatc agtcaaagct

421      gacttcccta cacctagtat atctgacttt gaaattccaa cttctaatat tagaaggata

481      atttgctcaa cctctggagg ttttccagag cctcacctct cctggttgga aaatggagaa

541      gaattaaatg ccatcaacac aacagtttcc caagatcctg aaactgagct ctatgctgtt

601      agcagcaaac tggatttcaa tatgacaacc aaccacagct tcatgtgtct catcaagtat

661      ggacatttaa gagtgaatca gaccttcaac tggaatacaa ccaagcaaga gcattttcct

721      gataacctgc tcccatcctg ggccattacc ttaatctcag taaatggaat ttttgtgata

781      tgctgcctga cctactgctt tgccccaaga tgcagagaga gaaggaggaa tgagagattg

841      agaagggaaa gtgtacgccc tgtataa
Nucleotide sequence in FASTA format (without gaps) B7A1*01

Amino acid sequence

1        MGHTRRQGTS PSKCPYLNFF QLLVLAGLSH FCSGVIHVTK EVKEVATLSC GHNVSVEELA

61       QTRIYWQKEK KMVLTMMSGD MNIWPEYKNR TIFDITNNLS IVILALRPSD EGTYECVVLK

121      YEKDAFKREH LAEVTLSVKA DFPTPSISDF EIPTSNIRRI ICSTSGGFPE PHLSWLENGE

181      ELNAINTTVS QDPETELYAV SSKLDFNMTT NHSFMCLIKY GHLRVNQTFN WNTTKQEHFP

241      DNLLPSWAIT LISVNGIFVI CCLTYCFAPR CRERRRNERL RRESVRPV*
Amino acid sequence in FASTA format (without gap) B7A1*01

Legend: