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Other B7 Family entries

IMGT RPI entry from gene to protein for Homo sapiens B7A2

Citing IMGT RPI entry for B7A2

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

B7A2 Gene exon/intron organization

Legend:

Number of alleles: 2

IMGT reference alleles

Allele names Gene functionality Clone names IMGT reference sequences
Exons Accession numbers Molecule type
B7A2*01 F EX1 U17715 [1] gDNA
EX2 U17717
EX3 U17718
EX4 U17719
EX5 U17720
EX6 U17721
EX7 U17722
B7A2*02 F EX1-EX7 L25259 [2] cDNA (1)

IMGT reference sequences (in FASTA format) for the allele(s): B7A2*01 to B7A2*02

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
B7A2*02 F EX1-EX7 EF064748 gDNA
U04343 cDNA
BC040261
NM_005191
EX2-EX7 CR541844 cDNA splicing B (3)
NM_006889

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
B7A2*01 U17715 329 aa 1
U17717 329 aa 1
U17718 329 aa 1
U17719 329 aa 1
U17720 329 aa 1
U17721 329 aa 1
U17722 329 aa 1
B7A2*02 L25259 P42081 329 aa 1
NM_005191 NP_008820 329 aa 1
NM_006889 NP_787058 323 aa 2
IMGT notes:
  1. (1) In EX3 [D1], g28>a; E10>K, positions are according to IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN.
  2. (2) No EX1. Utilizes alterative start codon located 4 bases after 5' ACCEPTOR-SPLICE site in EX2.
IMGT references:
  1. [1] Jellis,C.L., et al., Immunogenetics 42, 85-89 (1995). PMID: 7541777
  2. [2] Freeman,G.J., et al. Science 262, 909-911 (1993). PMID: 7694363

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

B7A2*01: U17715(g) U17717(g) U17718(g) U17719(g) U17720(g) U17721(g) U17722(g)

Nucleotide sequence

1        atggatcccc agtgcactat gggactgagt aacattctct ttgtgatggc cttcctgctc

61       tctggtgctg ctcctctgga gattcaagct tatttcaatg agactgcaga cctgccatgc

121      caatttgcaa actctcaaaa ccaaagcctg agtgagctag tagtattttg gcaggaccag

181      gaaaacttgg ttctgaatga ggtatactta ggcaaagaga aatttgacag tgttcattcc

241      aagtatatgg gccgcacaag ttttgattcg gacagttgga ccctgagact tcacaatctt

301      cagatcaagg acaagggctt gtatcaatgt atcatccatc acaaaaagcc cacaggaatg

361      attcgcatcc accagatgaa ttctgaactg tcagtgcttg ctaacttcag tcaacctgaa

421      atagtaccaa tttctaatat aacagaaaat gtgtacataa atttgacctg ctcatctata

481      cacggttacc cagaacctaa gaagatgagt gttttgctaa gaaccaagaa ttcaactatc

541      gagtatgatg gtattatgca gaaatctcaa gataatgtca cagaactgta cgacgtttcc

601      atcagcttgt ctgtttcatt ccctgatgtt acgagcaata tgaccatctt ctgtattctg

661      gaaactgaca agacgcggct tttatcttca cctttctcta tagagcttga ggaccctcag

721      cctcccccag accacattcc ttggattaca gctgtacttc caacagttat tatatgtgtg

781      atggttttct gtctaattct atggaaatgg aagaagaaga agcggcctcg caactcttat

841      aaatgtggaa ccaacacaat ggagagggaa gagagtgaac agaccaagaa aagagaaaaa

901      atccatatac ctgaaagatc tgatgaagcc cagcgtgttt ttaaaagttc gaagacatct

961      tcatgcgaca aaagtgatac atgtttttaa
Nucleotide sequence in FASTA format (without gaps) B7A2*01

Amino acid sequence

1        MDPQCTMGLS NILFVMAFLL SGAAPLEIQA YFNETADLPC QFANSQNQSL SELVVFWQDQ

61       ENLVLNEVYL GKEKFDSVHS KYMGRTSFDS DSWTLRLHNL QIKDKGLYQC IIHHKKPTGM

121      IRIHQMNSEL SVLANFSQPE IVPISNITEN VYINLTCSSI HGYPEPKKMS VLLRTKNSTI

181      EYDGIMQKSQ DNVTELYDVS ISLSVSFPDV TSNMTIFCIL ETDKTRLLSS PFSIELEDPQ

241      PPPDHIPWIT AVLPTVIICV MVFCLILWKW KKKKRPRNSY KCGTNTMERE ESEQTKKREK

301      IHIPERSDEA QRVFKSSKTS SCDKSDTCF*
Amino acid sequence in FASTA format (without gap) B7A2*01

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