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Other B7 Family entries

IMGT RPI entry from gene to protein for Homo sapiens B7DC

Citing IMGT RPI entry for B7DC

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

B7DC Gene exon/intron organization

Legend:

Number of alleles: 3

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
B7DC*01 F EX1-6 AL162253[1] gDNA
B7DC*02 F EX1-6 AF329193 cDNA (1)
B7DC*03 F EX1-6 EF444806 cDNA (2)

IMGT reference sequences (in FASTA format) for the allele(s): B7DC*01 to B7DC*03

Other sequences from the literature

Allele names Gene functionality Clone names IMGT reference sequences
Exons Accession numbers Molecule type
B7DC*01 F EX1-6 AF344424 cDNA
EX1-6 AY254343
MGC:103803 EX1-6 BC074766
MGC:142240 EX1-6 BC113680
EX1-6 NM_025239
EX1-6 DQ336699 cDNA partial EX1
EX1-2, 4-6 AY271901 cDNA (3) splicing B
EX1-2, 4-6 AY271902 cDNA, partial (4) splicing C

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
B7DC*01 AL162253 Tr:Q9BQ51 273 aa 1
B7DC*02 AF329193 273 aa 1
NM_025239 NP_079515 273 aa 1
AY271901 183 aa 2
AY271902 182 aa 3
B7DC*03 EF444806 273 aa 1
IMGT notes:
  1. (1) In EX4 t55>c; F19>S.
  2. (2) In EX4 t55>c; F19>S and a99>g; R34>G.
  3. (3) Splicing B (183 aa) has no EX3. New amino acid (S>G) at position 1 in EX4.
  4. (4) Splicing C (182 aa), partial. No EX3. Utlize an alternative 5'acceptor splice site 5 nt beyond the normal splice site leading to frameshift.

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

B7DC*01: AL162253(g)

Nucleotide sequence

1        atgatcttcc tcctgctaat gttgagcctg gaattgcagc ttcaccagat agcagcttta

61       ttcacagtga cagtccctaa ggaactgtac ataatagagc atggcagcaa tgtgaccctg

121      gaatgcaact ttgacactgg aagtcatgtg aaccttggag caataacagc cagtttgcaa

181      aaggtggaaa atgatacatc cccacaccgt gaaagagcca ctttgctgga ggagcagctg

241      cccctaggga aggcctcgtt ccacatacct caagtccaag tgagggacga aggacagtac

301      caatgcataa tcatctatgg ggtcgcctgg gactacaagt acctgactct gaaagtcaaa

361      gcttcctaca ggaaaataaa cactcacatc ctaaaggttc cagaaacaga tgaggtagag

421      ctcacctgcc aggctacagg ttatcctctg gcagaagtat cctggccaaa cgtcagcgtt

481      cctgccaaca ccagccactc caggacccct gaaggcctct accaggtcac cagtgttctg

541      cgcctaaagc caccccctgg cagaaacttc agctgtgtgt tctggaatac tcacgtgagg

601      gaacttactt tggccagcat tgaccttcaa agtcagatgg aacccaggac ccatccaact

661      tggctgcttc acattttcat ccccttctgc atcattgctt tcattttcat agccacagtg

721      atagccctaa gaaaacaact ctgtcaaaag ctgtattctt caaaagacac aacaaaaaga

781      cctgtcacca caacaaagag ggaagtgaac agtgctatct ga
Nucleotide sequence in FASTA format (without gaps) B7DC*01

Amino acid sequence

1        MIFLLLMLSL ELQLHQIAAL FTVTVPKELY IIEHGSNVTL ECNFDTGSHV NLGAITASLQ

61       KVENDTSPHR ERATLLEEQL PLGKASFHIP QVQVRDEGQY QCIIIYGVAW DYKYLTLKVK

121      ASYRKINTHI LKVPETDEVE LTCQATGYPL AEVSWPNVSV PANTSHSRTP EGLYQVTSVL

181      RLKPPPGRNF SCVFWNTHVR ELTLASIDLQ SQMEPRTHPT WLLHIFIPFC IIAFIFIATV

241      IALRKQLCQK LYSSKDTTKR PVTTTKREVN SAI*
Amino acid sequence in FASTA format (without gap) B7DC*01

Legend: