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Other B7 Family entries

IMGT RPI entry from gene to protein for Homo sapiens B7H1

Citing IMGT RPI entry for B7H1

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

B7H1 Gene exon/intron organization

Legend:

Number of alleles: 2

IMGT reference alleles

Allele names Gene functionality Clone name IMGT reference sequences
Exons Accession numbers Molecule type
B7H1*01 F RP11-57411 EX1-6 AL162253 gDNA
B7H1*02 F EX1-2 DQ836393 cDNA partial (1)

IMGT reference sequences (in FASTA format) for the allele(s): B7H1*01 to B7H1*02

Other sequences from the literature

Allele names Gene functionality Clone name IMGT reference sequences
Exons Accession numbers Molecule type
B7H1*01 F EX1-6 AF177937[1] cDNA splicing A
EX1-6 AF233516
EX1-6 AY254342
MGC:96999 EX1-6 BC069381
MGC:103912 EX1-6 BC074984
MGC:142294 EX1-6 BC113734
MGC:142296 EX1-6 BC113736
EX2-6 AK001894 splicing A partial EX1, EX2
EX1, 3-6 DQ286582 cDNA (2) splicing B
EX1, 3-6 AY291313
EX1-3 AY714881 cDNA splicing C (3)

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
B7H1*01 AF177937 Tr:Q9NZQ7 290 aa 1
NM_014143 NP_054862 290 aa 1
AY291313 Tr:Q9NZQ7-2 176 aa 2
AY714881 Tr:Q9NZQ7-3 178 aa 3
B7H1*02 DQ836393 126 aa 1
IMGT notes:
  1. (1) Partial sequence (126 aa). No EX3-6. In EX2 [D1] a305>t; Y102F, positions according to IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN.
  2. (2) Splicing B (176 aa). No EX2 [D1].
  3. (3) Splicing C (178 aa). EX3 [D2] has two internal splice sites.
IMGT references:
  1. [1] Dong H. et al. Nat. Med. 5, 1365-1369 (1999). PMID: 10581077

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

B7H1*01: AL162253(g)

Nucleotide sequence

1        atgaggatat ttgctgtctt tatattcatg acctactggc atttgctgaa cgcatttact

61       gtcacggttc ccaaggacct atatgtggta gagtatggta gcaatatgac aattgaatgc

121      aaattcccag tagaaaaaca attagacctg gctgcactaa ttgtctattg ggaaatggag

181      gataagaaca ttattcaatt tgtgcatgga gaggaagacc tgaaggttca gcatagtagc

241      tacagacaga gggcccggct gttgaaggac cagctctccc tgggaaatgc tgcacttcag

301      atcacagatg tgaaattgca ggatgcaggg gtgtaccgct gcatgatcag ctatggtggt

361      gccgactaca agcgaattac tgtgaaagtc aatgccccat acaacaaaat caaccaaaga

421      attttggttg tggatccagt cacctctgaa catgaactga catgtcaggc tgagggctac

481      cccaaggccg aagtcatctg gacaagcagt gaccatcaag tcctgagtgg taagaccacc

541      accaccaatt ccaagagaga ggagaagctt ttcaatgtga ccagcacact gagaatcaac

601      acaacaacta atgagatttt ctactgcact tttaggagat tagatcctga ggaaaaccat

661      acagctgaat tggtcatccc agaactacct ctggcacatc ctccaaatga aaggactcac

721      ttggtaattc tgggagccat cttattatgc cttggtgtag cactgacatt catcttccgt

781      ttaagaaaag ggagaatgat ggatgtgaaa aaatgtggca tccaagatac aaactcaaag

841      aagcaaagtg atacacattt ggaggagacg taa
Nucleotide sequence in FASTA format (without gaps) B7H1*01

Amino acid sequence

1        MRIFAVFIFM TYWHLLNAFT VTVPKDLYVV EYGSNMTIEC KFPVEKQLDL AALIVYWEME

61       DKNIIQFVHG EEDLKVQHSS YRQRARLLKD QLSLGNAALQ ITDVKLQDAG VYRCMISYGG

121      ADYKRITVKV NAPYNKINQR ILVVDPVTSE HELTCQAEGY PKAEVIWTSS DHQVLSGKTT

181      TTNSKREEKL FNVTSTLRIN TTTNEIFYCT FRRLDPEENH TAELVIPELP LAHPPNERTH

241      LVILGAILLC LGVALTFIFR LRKGRMMDVK KCGIQDTNSK KQSDTHLEET *
Amino acid sequence in FASTA format (without gap) B7H1*01

Legend: