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IMGT RPI entry from gene to protein for Homo sapiens BTLA

Citing IMGT RPI entry for BTLA

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

BTLA Gene exon/intron organization

Legend:

Number of alleles: 4

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
BTLA*01 F EX1-5 AJ717664 cDNA
BTLA*02 F EX1-5 NM_181780 gDNA(1)
BTLA*03 F EX1-5 AK131204 cDNA(2)
BTLA*04 F EX1-5 AY293286 cDNA(3)

IMGT reference sequences (in FASTA format) for the allele(s): BTLA*01 to BTLA*04

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
BTLA*01 F EX1-5 BC107092 cDNA
BC120602 cDNA
EX1-2, EX4-5 DQ198368(4) cDNA splicingB

Corresponding protein database accession numbers

BTLA Accession numbers Number of amino acids Protein isoform
Nucleotide Databases Protein Databases
BTLA*01 AJ717664 Q02242 289 aa 1
BTLA*02 NM_181780 NP_032824 289 aa 1
BTLA*03 AK131204 283 aa
BTLA*04 AY293286 289 aa
IMGT notes:
  1. (1) In EX2, t273>c numbering according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
  2. (2) In EX2, t273>c numbering according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN and in EX5 t62>c; L21>P.
  3. (3) mutations are many.
  4. (4) No EX3.

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

BTLA*01: AJ717664(c)

Nucleotide sequence

1        atgaagacat tgcctgccat gcttggaact gggaaattat tttgggtctt cttcttaatc

61       ccatatctgg acatctggaa catccatggg aaagaatcat gtgatgtaca gctttatata

121      aagagacaat ctgaacactc catcttagca ggagatccct ttgaactaga atgccctgtg

181      aaatactgtg ctaacaggcc tcatgtgact tggtgcaagc tcaatggaac aacatgtgta

241      aaacttgaag atagacaaac aagttggaag gaagagaaga acatttcatt tttcattcta

301      cattttgaac cagtgcttcc taatgacaat gggtcatacc gctgttctgc aaattttcag

361      tctaatctca ttgaaagcca ctcaacaact ctttatgtga cagatgtaaa aagtgcctca

421      gaacgaccct ccaaggacga aatggcaagc agaccctggc tcctgtatag tttacttcct

481      ttggggggat tgcctctact catcactacc tgtttctgcc tgttctgctg cctgagaagg

541      caccaaggaa agcaaaatga actctctgac acagcaggaa gggaaattaa cctggttgat

601      gctcacctta agagtgagca aacagaagca agcaccaggc aaaattccca agtactgcta

661      tcagaaactg gaatttatga taatgaccct gacctttgtt tcaggatgca ggaagggtct

721      gaagtttatt ctaatccatg cctggaagaa aacaaaccag gcattgttta tgcttccctg

781      aaccattctg tcattggact gaactcaaga ctggcaagaa atgtaaaaga agcaccaaca

841      gaatatgcat ccatatgtgt gaggagttaa
Nucleotide sequence in FASTA format (without gaps) BTLA*01

Amino acid sequence

1        MKTLPAMLGT GKLFWVFFLI PYLDIWNIHG KESCDVQLYI KRQSEHSILA GDPFELECPV

61       KYCANRPHVT WCKLNGTTCV KLEDRQTSWK EEKNISFFIL HFEPVLPNDN GSYRCSANFQ

121      SNLIESHSTT LYVTDVKSAS ERPSKDEMAS RPWLLYSLLP LGGLPLLITT CFCLFCCLRR

181      HQGKQNELSD TAGREINLVD AHLKSEQTEA STRQNSQVLL SETGIYDNDP DLCFRMQEGS

241      EVYSNPCLEE NKPGIVYASL NHSVIGLNSR LARNVKEAPT EYASICVRS*
Amino acid sequence in FASTA format (without gap) BTLA*01

Legend: