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Other CD3 entries

IMGT RPI entry from gene to protein for Homo sapiens CD3E

Citing IMGT RPI entry for CD3E

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CD3E Gene exon/intron organization

Legend:

Number of alleles: 2

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
CD3E*01 F EX1 M23317 [1] gDNA
EX2 M23318 gDNA
EX3 M23319 gDNA
EX4 M23320 gDNA
EX5 M23321 gDNA
EX6 L34846 gDNA
EX7 M23322 gDNA
EX8 M23323 gDNA
CD3E*02 F EX1-8 X03884 [2] cDNA (1)

IMGT reference sequences (in FASTA format) for the allele(s): CD3E*01 to CD3E*02

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Clone names Exons Accession numbers Molecule type
CD3E*01 F EX1-8 BC049847 cDNA
NM_000733

Corresponding protein database accession numbers

CD3E Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CD3E*01 M23317 P07766 207 aa 1
M23318 207 aa 1
M23319 207 aa 1
M23320 207 aa 1
M23321 207 aa 1
L34846 207 aa 1
M23322 207 aa 1
M23323 207 aa 1
NM_000733 NP_000724 207 aa 1
CD3E*02 X03884 P07766 207 aa 1
IMGT notes:
  1. (1) In EX2[D] t5>c, positions according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
IMGT references:
  1. [1] Clevers ,H.C. et all, Natl. Acad. Sci. U.S.A. 85, 8156-8160 (1988). PMID: 3267235
  2. [2] Gold, D.P. et all, Nature 321, 431-434 (1986). PMID: 3012357

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CD3E*01: M23317(g) M23318(g) M23319(g) M23320(g) M23321(g) L34846(g) M23322(g) M23323(g)

Nucleotide sequence

1        atgcagtcgg gcactcactg gagagttctg ggcctctgcc tcttatcagt tggtgtttgg

61       gggcaagatg gtaatgaaga aatgggtggt attacacaga caccatataa agtctccatc

121      tctggaacca cagtaatatt gacatgccct cagtatcctg gatctgaaat actatggcaa

181      cacaatgata aaaacatagg cggtgatgag gatgataaaa acataggcag tgatgaggat

241      cacctgtcac tgaaggaatt ttcagaattg gagcaaagtg gttattatgt ctgctacccc

301      agaggaagca aaccagaaga tgcgaacttt tatctctacc tgagggcaag agtgtgtgag

361      aactgcatgg agatggatgt gatgtcggtg gccacaattg tcatagtgga catctgcatc

421      actgggggct tgctgctgct ggtttactac tggagcaaga atagaaaggc caaggccaag

481      cctgtgacac gaggagcggg tgctggcggc aggcaaaggg gacaaaacaa ggagaggcca

541      ccacctgttc ccaacccaga ctatgagccc atccggaaag gccagcggga cctgtattct

601      ggcctgaatc agagacgcat ctga
Nucleotide sequence in FASTA format (without gaps) CD3E*01

Amino acid sequence

1        MQSGTHWRVL GLCLLSVGVW GQDGNEEMGG ITQTPYKVSI SGTTVILTCP QYPGSEILWQ

61       HNDKNIGGDE DDKNIGSDED HLSLKEFSEL EQSGYYVCYP RGSKPEDANF YLYLRARVCE

121      NCMEMDVMSV ATIVIVDICI TGGLLLLVYY WSKNRKAKAK PVTRGAGAGG RQRGQNKERP

181      PPVPNPDYEP IRKGQRDLYS GLNQRRI*
Amino acid sequence in FASTA format (without gap) CD3E*01

Legend: