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Other CD7 entries

IMGT RPI entry from gene to protein for Homo sapiens CD7

Citing IMGT RPI entry for CD7

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CD7 Gene exon/intron organization

Legend:

Number of alleles: 5

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
CD7*01 F EX1-4 M37271 [1] gDNA
CD7*02 F EX1-4 AY935536 cDNA (1)
CD7*03 F EX1-4 AK223465 [2] cDNA (2)
CD7*04 F EX1-4 AY935534 cDNA (3)
CD7*05 F EX1-4 AY935535 cDNA (4)

IMGT reference sequences (in FASTA format) for the allele(s): CD7*01 to CD7*05

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type Partiality
CD7*01 F EX1-4 AC132872 (28474..31208) gDNA
D00749 gDNA
BC009293 cDNA
BC013297 cDNA
EX1-4 BT006696 cDNA
EX1-4 X06180 cDNA
AY935537 cDNA (5) partial
EX1-2 BM917451 cDNA

Corresponding protein database accession numbers

Allele Name Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CD7*01 M37271 P09564 240 aa 1
NM_006137 NP_006128 240 aa 1
AY935537 Q29VG2 236 aa 1
CD7*02 AY935536 P09564 240 aa 1
CD7*03 AK223465 Q53F24 240 aa 1
CD7*04 AY935534 240 aa 1
CD7*05 AY935535 240 aa 1
IMGT notes:
  1. (1) In EX3 146g>a.
  2. (2) In EX3 55c>t; 18A>V.
  3. (3) In EX3 103c>t; 34A>V.
  4. (4) In EX3 205c>t; 68A>V.
  5. (5) AY935537 was considered as partial because in EX2, it has twelve deletions.
IMGT references:
  1. [1] Schanberg L.E. et al, Proc. Natl. Acad. Sci. USA 88, 603-607 (1991). PMID: 1703303
  2. [2] Maruyama K. and Sugano S., Gene 138,171-174 (1994). PMID: 8125298

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CD7*01: M37271(g)

Nucleotide sequence

1        atggccgggc ctccgaggct cctgctgctg cccctgcttc tggcgctggc tcgcggcctg

61       cctggggccc tggctgccca agaggtgcag cagtctcccc actgcacgac tgtccccgtg

121      ggagcctccg tcaacatcac ctgctccacc agcgggggcc tgcgtgggat ctacctgagg

181      cagctcgggc cacagcccca agacatcatt tactacgagg acggggtggt gcccactacg

241      gacagacggt tccggggccg catcgacttc tcagggtccc aggacaacct gactatcacc

301      atgcaccgcc tgcagctgtc ggacactggc acctacacct gccaggccat cacggaggtc

361      aatgtctacg gctccggcac cctggtcctg gtgacagagg aacagtccca aggatggcac

421      agatgctcgg acgccccacc aagggcctct gccctccctg ccccaccgac aggctccgcc

481      ctccctgacc cgcagacagc ctctgccctc cctgacccgc cagcagcctc tgccctccct

541      gcggccctgg cggtgatctc cttcctcctc gggctgggcc tgggggtggc gtgtgtgctg

601      gcgaggacac agataaagaa actgtgctcg tggcgggata agaattcggc ggcatgtgtg

661      gtgtacgagg acatgtcgca cagccgctgc aacacgctgt cctcccccaa ccagtaccag

721      tga
Nucleotide sequence in FASTA format (without gaps) CD7*01

Amino acid sequence

1        MAGPPRLLLL PLLLALARGL PGALAAQEVQ QSPHCTTVPV GASVNITCST SGGLRGIYLR

61       QLGPQPQDII YYEDGVVPTT DRRFRGRIDF SGSQDNLTIT MHRLQLSDTG TYTCQAITEV

121      NVYGSGTLVL VTEEQSQGWH RCSDAPPRAS ALPAPPTGSA LPDPQTASAL PDPPAASALP

181      AALAVISFLL GLGLGVACVL ARTQIKKLCS WRDKNSAACV VYEDMSHSRC NTLSSPNQYQ

241      *
Amino acid sequence in FASTA format (without gap) CD7*01

Legend: