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Other CD79 entries

IMGT RPI entry from gene to protein for Homo sapiens CD79A

Citing IMGT RPI entry for CD79A

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CD79A Gene exon/intron organization

Legend:

Number of alleles: 4

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
CD79A*01 F EX1-5 U05259 [1] gDNA
CD79A*02 F EX1-5 M74721 [2] cDNA (1)
CD79A*03 F EX1-5 AK223371 cDNA (2)
CD79A*04 F EX5 X13451 [3] cDNA (3)

IMGT reference sequences (in FASTA format) for the allele(s): CD79A*01 to CD79A*04

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
CD79A*01 F EX1-5 L32754 gDNA
AC010616 (38339..42576) gDNA
M86921 cDNA
M80462 cDNA
BC113731 cDNA
BC113733 cDNA
S46706 cDNA
S75217 cDNA
S79248 cDNA (4) splicing B
X83540 cDNA splicing B
NM_001783 cDNA
NM_021601 cDNA splicing B

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CD79A*01 U05259 P11912 226 aa 1
NM_001783 NP_001774 226 aa 1
NM_021601 NP_067612 188 aa 2
CD79A*02 M74721 226 aa 1
CD79A*03 AK223371 Tr:Q53FB8 226 aa 1
CD79A*04 X13451 54 aa 3
IMGT notes:
  1. (1) In EX2 [D] g130>a; V44I, positions according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
  2. (2) In EX2 [D] g47>t; G16>V, positions according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN and in EX4 a68>g; E23>G.
  3. (3) Splicing C (54 aa). Partial cDNA, no EX1-4. EX5 of this transcript has an internal splice site and utilizes a new exon (EX6) of 59 nt. In EX5 g89>c; G30>A.
  4. (4) Splicing B (188 aa). EX2 has an internal splice site. In EX3 Q1>E is the amino acid encoded by the new codon created by alternative splicing.
IMGT references:
  1. [1] Ha H.et al., J. Immunol. 152, 5749-5757 (1994). PMID: 8207205
  2. [2] Flaswinkel H. and Reth M. Immunogenetics 36, 266-269 (1992). PMID: 1639443
  3. [3] Sakaguchi N et al., EMBO J. 7, 3457-3464 (1988). PMID: 2463161

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CD79A*01: U05259(g)

Nucleotide sequence

1        atgcctgggg gtccaggagt cctccaagct ctgcctgcca ccatcttcct cctcttcctg

61       ctgtctgctg tctacctggg ccctgggtgc caggccctgt ggatgcacaa ggtcccagca

121      tcattgatgg tgagcctggg ggaagacgcc cacttccaat gcccgcacaa tagcagcaac

181      aacgccaacg tcacctggtg gcgcgtcctc catggcaact acacgtggcc ccctgagttc

241      ttgggcccgg gcgaggaccc caatggtacg ctgatcatcc agaatgtgaa caagagccat

301      gggggcatat acgtgtgccg ggtccaggag ggcaacgagt cataccagca gtcctgcggc

361      acctacctcc gcgtgcgcca gccgcccccc aggcccttcc tggacatggg ggagggcacc

421      aagaaccgaa tcatcacagc cgaggggatc atcctcctgt tctgcgcggt ggtgcctggg

481      acgctgctgc tgttcaggaa acgatggcag aacgagaagc tcgggttgga tgccggggat

541      gaatatgaag atgaaaacct ttatgaaggc ctgaacctgg acgactgctc catgtatgag

601      gacatctccc ggggcctcca gggcacctac caggatgtgg gcagcctcaa cataggagat

661      gtccagctgg agaagccgtg a
Nucleotide sequence in FASTA format (without gaps) CD79A*01

Amino acid sequence

1        MPGGPGVLQA LPATIFLLFL LSAVYLGPGC QALWMHKVPA SLMVSLGEDA HFQCPHNSSN

61       NANVTWWRVL HGNYTWPPEF LGPGEDPNGT LIIQNVNKSH GGIYVCRVQE GNESYQQSCG

121      TYLRVRQPPP RPFLDMGEGT KNRIITAEGI ILLFCAVVPG TLLLFRKRWQ NEKLGLDAGD

181      EYEDENLYEG LNLDDCSMYE DISRGLQGTY QDVGSLNIGD VQLEKP*
Amino acid sequence in FASTA format (without gap) CD79A*01

Legend: