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Other CD79 entries

IMGT RPI entry from gene to protein for Homo sapiens CD79B

Citing IMGT RPI entry for CD79B

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CD79B Gene exon/intron organization

Legend:

Number of alleles: 4

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
CD79B*01 F EX1-6 U05259 [1] gDNA
CD79B*02 F EX1-6 BC002975 cDNA (1)
CD79B*03 F EX1-6 M80461 cDNA (2)
CD79B*04 F EX1-6 S52229 [2] cDNA (3)

IMGT reference sequences (in FASTA format) for the allele(s): CD79B*01 to CD79B*04

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
CD79B*01 F EX1-6 AK222954 cDNA (4) splicing B
AK223210 cDNA splicing B
EX1-2,4-6 X83539 cDNA (5) splicing C
S79249 cDNA (5) splicing C
EX1 BC030210 cDNA
EX1-6 NM_000626 cDNA splicing A
NM_001039933 cDNA splicing B
EX1-2,4-6 NM_021602 cDNA splicing C
CD79B*02 EX1-6 BC032651 cDNA

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CD79B*01 U05259 P40259 229 aa 1
NM_000626 NP_000617 229 aa 1
NM_001039933 NP_001035022 230 aa 2
NM_021602 NP_067613 125 aa 3
CD79B*02 BC002975 229 aa 1
CD79B*03 M80461 229 aa 1
CD79B*04 S52229 229 aa 1
IMGT notes:
  1. (1) In EX3 [D] c312>t positions according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
  2. (2) In EX3 [D] g46>c, G16>R and c312>t, positions according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
  3. (3) In EX1 g48>t and in EX3 [D] g46>c, G16>R and c312>t, positions according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
  4. (4) Splicing B (230 aa). This transcipt uses an alternative in-frame splice site in the EX2 5' ACCEPTOR-SPLICE site one codon upstream to the usual splice site.
  5. (5) Splicing C (125 aa). This transcript is the smallest and lacks the EX3 [D] encoding the C-LIKE-DOMAIN.
IMGT references:
  1. [1] Hashimoto S. Chiorazzi N. and Gregersen P.K. Immunogenetics 40, 145-149 (1994). PMID: 7913081
  2. [2] Hashimoto S. Gregersen P.K. and Chiorazzi N. J. Immunol. 150, 491-498 (1993) . PMID: 8419481

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CD79B*01: L27587(g)

Nucleotide sequence

1        atggccaggc tggcgttgtc tcctgtgccc agccactgga tggtggcgtt gctgctgctg

61       ctctcagctg agccagtacc agcagccaga tcggaggacc ggtaccggaa tcccaaaggt

121      agtgcttgtt cgcggatctg gcagagccca cgtttcatag ccaggaaacg gggcttcacg

181      gtgaaaatgc actgctacat gaacagcgcc tccggcaatg tgagctggct ctggaagcag

241      gagatggacg agaatcccca gcagctgaag ctggaaaagg gccgcatgga agagtcccag

301      aacgaatctc tcgccaccct caccatccaa ggcatccggt ttgaggacaa tggcatctac

361      ttctgtcagc agaagtgcaa caacacctcg gaggtctacc agggctgcgg cacagagctg

421      cgagtcatgg gattcagcac cttggcacag ctgaagcaga ggaacacgct gaaggatggt

481      atcatcatga tccagacgct gctgatcatc ctcttcatca tcgtgcctat cttcctgctg

541      ctggacaagg atgacagcaa ggctggcatg gaggaagatc acacctacga gggcctggac

601      attgaccaga cagccaccta tgaggacata gtgacgctgc ggacagggga agtgaagtgg

661      tctgtaggtg agcacccagg ccaggagtga
Nucleotide sequence in FASTA format (without gaps) CD79B*01

Amino acid sequence

1        MARLALSPVP SHWMVALLLL LSAEPVPAAR SEDRYRNPKG SACSRIWQSP RFIARKRGFT

61       VKMHCYMNSA SGNVSWLWKQ EMDENPQQLK LEKGRMEESQ NESLATLTIQ GIRFEDNGIY

121      FCQQKCNNTS EVYQGCGTEL RVMGFSTLAQ LKQRNTLKDG IIMIQTLLII LFIIVPIFLL

181      LDKDDSKAGM EEDHTYEGLD IDQTATYEDI VTLRTGEVKW SVGEHPGQE*
Amino acid sequence in FASTA format (without gap) CD79B*01

Legend: