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IMGT RPI entry from gene to protein for Homo sapiens CD84

Citing IMGT RPI entry for CD84

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CD84 Gene exon/intron organization

Legend:

Number of alleles: 1

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
CD84*01 F EX1-8 AF054816 cDNA

IMGT reference sequences (in FASTA format) for the allele(s): CD84*01

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
CD84*01 F EX1-8 Y12632 cDNA splicing B (1)
EX1-7 U82988 [1] cDNA splicing C (2)
BC020063 cDNA
AL138930 gDNA
EX1-4c U96627 cDNA splicing D (3)
EX1-4, 7b AF054817 cDNA splicing E (4)
EX1-3b AF054818 cDNA splicing F (5)

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CD84*01 AF054816 Tr: Q9UIB8 345 aa 1
Y12632 Tr: Q8WWI8 339 aa 2
U82988 O15430 328 aa 3
U96627 O95660 280 aa 4
AF054817 Tr: Q9UIB7 272 aa 5
AF054818 Tr: Q9UIB6 241 aa 6
NM_003874 NP_003865 328 aa 3
IMGT notes:
  1. (1) Splicing B (339 aa). Alternative splicing site in EX4 19 bp upstream of the normal 3' splice site.
  2. (2) Splicing C (328 aa). Alternative splicing site in EX4 19 bp upstream of the normal 3' splice site and no EX5.
  3. (3) Splicing D (280 aa). No splicing site in EX4, 83 bp extend beyond the normal site and terminate prematurely.
  4. (4) Splicing E (272 aa). No EX5-6. This frame shift caus the premature termination with in EX7.
  5. (5) Splicing F (241 aa). No 3' splice site in EX3. This cause the premature termination.
IMGT references:
  1. [1] de la Funte MA. et al, Blood 90, 2398-2405 (1997) . PMID: 9310491

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CD84*01: AF054816(c)

Nucleotide sequence

1        atggctcagc accacctatg gatcttgctc ctttgcctgc aaacctggcc ggaagcagct

61       ggaaaagact cagaaatctt cacagtgaat gggattctgg gagagtcagt cactttccct

121      gtaaatatcc aagaaccacg gcaagttaaa atcattgctt ggacttctaa aacatctgtt

181      gcttatgtaa caccaggaga ctcagaaaca gcacccgtag ttactgtgac ccacagaaat

241      tattatgaac ggatacatgc cttaggtccg aactacaatc tggtcattag cgatctgagg

301      atggaagacg caggagacta caaagcagac ataaatacac aggctgatcc ctacaccacc

361      accaagcgct acaacctgca aatctatcgt cggcttggga aaccaaaaat tacacagagt

421      ttaatggcat ctgtgaacag cacctgtaat gtcacactga catgctctgt agagaaagaa

481      gaaaagaatg tgacatacaa ttggagtccc ctgggagaag agggtaatgt ccttcaaatc

541      ttccagactc ctgaggacca agagctgact tacacgtgta cagcccagaa ccctgtcagc

601      aacaattctg actccatctc tgcccggcag ctctgtgcag acatcgcaat gggcttccgt

661      actcaccaca ccgggttgct gagcgtgctg gctatgttct ttctgcttgt tctcattctg

721      tcttcagtgt ttttgttccg tttgttcaag agaagacaag atgctgcctc aaagaaaacc

781      atatacacat atatcatggc ttcaaggaac acccagccag cagagtccag aatctatgat

841      gaaatcctgc agtccaaggt gcttccctcc aaggaagagc cagtgaacac agtttattcc

901      gaagtgcagt ttgctgataa gatggggaaa gccagcacac aggacagtaa acctcctggg

961      acttcaagct atgaaattgt gatctag
Nucleotide sequence in FASTA format (without gaps) CD84*01

Amino acid sequence

1        MAQHHLWILL LCLQTWPEAA GKDSEIFTVN GILGESVTFP VNIQEPRQVK IIAWTSKTSV

61       AYVTPGDSET APVVTVTHRN YYERIHALGP NYNLVISDLR MEDAGDYKAD INTQADPYTT

121      TKRYNLQIYR RLGKPKITQS LMASVNSTCN VTLTCSVEKE EKNVTYNWSP LGEEGNVLQI

181      FQTPEDQELT YTCTAQNPVS NNSDSISARQ LCADIAMGFR THHTGLLSVL AMFFLLVLIL

241      SSVFLFRLFK RRQDAASKKT IYTYIMASRN TQPAESRIYD EILQSKVLPS KEEPVNTVYS

301      EVQFADKMGK ASTQDSKPPG TSSYEIVI*
Amino acid sequence in FASTA format (without gap) CD84*01

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