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IMGT RPI entry from gene to protein for Homo sapiens CEACAM1

Citing IMGT RPI entry for CEACAM1

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CEACAM1 Gene exon/intron organization

Legend:

Number of alleles: 2

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
CEACAM1*01 F EX1-5, EX7-10 AC004785 gDNA
CEACAM1*02 F EX1-4, EX6-10 D12502 [1] cDNA (1) splicing B

IMGT reference sequences (in FASTA format) for the allele(s): CEACAM1*01 to CEACAM1*02

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Exons Accession numbers Molecule type
CEACAM1*01 F EX1-5, EX7-10 J03858 cDNA
X16354 cDNA
EX1-5, EX7, EX9 A43165 gDNA Splicing C
EX1-4, EX7-10 X14831 cDNA Splicing D
EX1-2, EX7-10 M76742 cDNA Splicing E
EX1-4, EX7, EX9 AY766113 cDNA Splicing F
EX1-3, EX4L M69176 cDNA Splicing G
EX1-4, EX5L D90311 cDNA Splicing H
EX1-4, EX5p D90313 cDNA Splicing I
EX1 X67277 gDNA
EX1-5, EX7-10 NM_001712 cDNA
EX1-5, EX7, EX9 NM_001024912 cDNA

Corresponding protein database accession numbers

Allele Name Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CEACAM1*01 J03858 P13688 526aa 1
NM_001712 NP_001703 526aa 1
NM_001024912 NP_001020083 464aa 2
IMGT notes:
  1. (1) [EX4L and EX5L] represent the exons in which the usual DONOR-SPLICE is not used. As a consequence, the translation continues beyond this DONOR-SPLICE until the first STOP-CODON, in frame, in the downstream intron.
  2. (2) [EX5p] represents an exon which is partial in 5'.
  3. (3) Splicing C and F result from a premature STOP-CODON.
  4. (4) Splicing A and splicing B are named Isoform 1 and 2, respectively.
  5. (5) Splicing G, H and I are named BGPg, BGPh and BGPi, respectively.
  6. (6) In EX4 [D3] 28g>t; 10D>Y, positions according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN and in EX8 43c>g.
IMGT references:
  1. [1] Hinoda Y. et al., Proc.Natl. Acad. Sci. USA. 85, 6959-6963 (1988). PMID: 2457922

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CEACAM1*01: AC004785(g)

Nucleotide sequence

1        atggggcacc tctcagcccc acttcacaga gtgcgtgtac cctggcaggg gcttctgctc

61       acagcctcac ttctaacctt ctggaacccg cccaccactg cccagctcac tactgaatcc

121      atgccattca atgttgcaga ggggaaggag gttcttctcc ttgtccacaa tctgccccag

181      caactttttg gctacagctg gtacaaaggg gaaagagtgg atggcaaccg tcaaattgta

241      ggatatgcaa taggaactca acaagctacc ccagggcccg caaacagcgg tcgagagaca

301      atatacccca atgcatccct gctgatccag aacgtcaccc agaatgacac aggattctac

361      accctacaag tcataaagtc agatcttgtg aatgaagaag caactggaca gttccatgta

421      tacccggagc tgcccaagcc ctccatctcc agcaacaact ccaaccctgt ggaggacaag

481      gatgctgtgg ccttcacctg tgaacctgag actcaggaca caacctacct gtggtggata

541      aacaatcaga gcctcccggt cagtcccagg ctgcagctgt ccaatggcaa caggaccctc

601      actctactca gtgtcacaag gaatgacaca ggaccctatg agtgtgaaat acagaaccca

661      gtgagtgcga accgcagtga cccagtcacc ttgaatgtca cctatggccc ggacaccccc

721      accatttccc cttcagacac ctattaccgt ccaggggcaa acctcagcct ctcctgctat

781      gcagcctcta acccacctgc acagtactcc tggcttatca atggaacatt ccagcaaagc

841      acacaagagc tctttatccc taacatcact gtgaataata gtggatccta tacctgccac

901      gccaataact cagtcactgg ctgcaacagg accacagtca agacgatcat agtcactgag

961      ctaagtccag tagtagcaaa gccccaaatc aaagccagca agaccacagt cacaggagat

1021     aaggactctg tgaacctgac ctgctccaca aatgacactg gaatctccat ccgttggttc

1081     ttcaaaaacc agagtctccc gtcctcggag aggatgaagc tgtcccaggg caacaccacc

1141     ctcagcataa accctgtcaa gagggaggat gctgggacgt attggtgtga ggtcttcaac

1201     ccaatcagta agaaccaaag cgaccccatc atgctgaacg taaactataa tgctctacca

1261     caagaaaatg gcctctcacc tggggccatt gctggcattg tgattggagt agtggccctg

1321     gttgctctga tagcagtagc cctggcatgt tttctgcatt tcgggaagac cggcagggca

1381     agcgaccagc gtgatctcac agagcacaaa ccctcagtct ccaaccacac tcaggaccac

1441     tccaatgacc cacctaacaa gatgaatgaa gttacttatt ctaccctgaa ctttgaagcc

1501     cagcaaccca cacaaccaac ttcagcctcc ccatccctaa cagccacaga aataatttat

1561     tcagaagtaa aaaagcagta a
Nucleotide sequence in FASTA format (without gaps) CEACAM1*01

Amino acid sequence

1        MGHLSAPLHR VRVPWQGLLL TASLLTFWNP PTTAQLTTES MPFNVAEGKE VLLLVHNLPQ

61       QLFGYSWYKG ERVDGNRQIV GYAIGTQQAT PGPANSGRET IYPNASLLIQ NVTQNDTGFY

121      TLQVIKSDLV NEEATGQFHV YPELPKPSIS SNNSNPVEDK DAVAFTCEPE TQDTTYLWWI

181      NNQSLPVSPR LQLSNGNRTL TLLSVTRNDT GPYECEIQNP VSANRSDPVT LNVTYGPDTP

241      TISPSDTYYR PGANLSLSCY AASNPPAQYS WLINGTFQQS TQELFIPNIT VNNSGSYTCH

301      ANNSVTGCNR TTVKTIIVTE LSPVVAKPQI KASKTTVTGD KDSVNLTCST NDTGISIRWF

361      FKNQSLPSSE RMKLSQGNTT LSINPVKRED AGTYWCEVFN PISKNQSDPI MLNVNYNALP

421      QENGLSPGAI AGIVIGVVAL VALIAVALAC FLHFGKTGRA SDQRDLTEHK PSVSNHTQDH

481      SNDPPNKMNE VTYSTLNFEA QQPTQPTSAS PSLTATEIIY SEVKKQ*
Amino acid sequence in FASTA format (without gap) CEACAM1*01

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