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IMGT RPI entry from gene to protein for Homo sapiens VPREB1

Citing IMGT RPI entry for VPREB1

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

VPREB1 Gene exon/intron organization

Legend:

Number of alleles: 2

IMGT reference alleles

Allele names Gene functionality Clone name IMGT reference sequences
Exons Accession numbers Molecule type
VPREB1*01 F EX1-2 S74019[1] gDNA
VPREB1*02 F pHVPB-6 EX1-2 M34927 [2] gDNA (1) partial

IMGT reference sequences (in FASTA format) for the allele(s): VPREB1*01 to VPREB1*02

Other sequences from the literature

Allele names Gene functionality Clone name IMGT reference sequences
Exons Accession numbers Molecule type
VPREB1*01 F 123E1 EX1-2 D86992 gDNA
EX1-2 D88270
C22ORF:pGEM.VPREB1 EX1-2 CR456609 cDNA
. EX1-2 NM_007128

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
VPREB1*01 S74019 P12018 145 aa 1
NM_007128 NP_009059 145 aa 1
VPREB1*02 M34927 P12018 139 aa 1 partial
IMGT notes:
  1. (1) Partial (189 aa), six codons in the 3' region are missing. In EX1 t29>g and g30>c; L10>H. In EX2 [D] g12>a, positions according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
IMGT references:
  1. [1] Guelpa-Fonlupt V. et al, Mol. Immunol. 31, 1099-1108 (1994). PMID: 7935499
  2. [2] Bauer S.R. Kudo A. and Melchers F. EMBO J. 7, 111-116 (1988). PMID: 3258819

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

VPREB1*01: S74019(g)

Nucleotide sequence

1        atgtcctggg ctcctgtcct gctcatgctg tttgtctact gcacaggttg tggtcctcag

61       ccggtgctgc atcagccgcc ggccatgtcc tcggcccttg gaaccacaat ccgcctcacc

121      tgcaccctga ggaacgacca tgacatcggt gtgtacagcg tctactggta ccagcagagg

181      ccgggccacc ctcccaggtt cctgctgaga tatttctcac aatcagacaa gagccagggc

241      ccccaggtcc cccctcgctt ctctggatcc aaagatgtgg ccaggaacag ggggtatttg

301      agcatctctg agctgcagcc tgaggacgag gctatgtatt actgtgctat gggggcccgc

361      agctcggaga aggaggagag ggagagggag tgggaggaag aaatggaacc cactgcagcc

421      aggacacgtg tcccttga
Nucleotide sequence in FASTA format (without gaps) VPREB1*01

Amino acid sequence

1        MSWAPVLLML FVYCTGCGPQ PVLHQPPAMS SALGTTIRLT CTLRNDHDIG VYSVYWYQQR

61       PGHPPRFLLR YFSQSDKSQG PQVPPRFSGS KDVARNRGYL SISELQPEDE AMYYCAMGAR

121      SSEKEERERE WEEEMEPTAA RTRVP*
Amino acid sequence in FASTA format (without gap) VPREB1*01

Legend: