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Other B7 Family entries

IMGT RPI entry from gene to protein for Mus musculus B7A2

Citing IMGT RPI entry for B7A2

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

B7A2 Gene exon/intron organization

Legend:

Number of alleles: 4

IMGT reference alleles

Allele names Gene functionality Strains IMGT reference sequences
Exons Accession numbers Molecule type
B7A2*01 F 129 EX1 U39456[1] gDNA
EX2 U39457
EX6 U39461
EX7 U39462
EX8 U39463
EX9 U39464
EX10 U39465
EX11 U39466
B7A2*02 F NOD EX4, 6-11 AK172548 cDNA (2) splicing B
B7A2*03 F NOD EX4, 6-11 AK170054 cDNA (3) splicing B
B7A2*04 F CHECHII EX4, 6-11 BC013807 cDNA (4) splicing B

IMGT reference sequences (in FASTA format) for the allele(s): B7A2*01 to B7A2*04

Other sequences from the literature

Allele names Gene functionality Strains IMGT reference sequences
Exons Accession numbers Molecule type
B7A2*01 F C57BL/6J EX3-EX8 AF065898 cDNA splicing B
EX3-EX8 AK079513
B10.S/J EX3-EX8 AF065899
SJL/J EX3-EX8 AF065900
A/J EX3-EX8 AF065897
EX3-EX8 L25606
EX3-EX8 S70108
B7A2*04 F EX3-EX8 NM_019388 cDNA splicing B

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
B7A2*01 U39456 Q64381 356 aa 1
U39457 356 aa 1
U39462 356 aa 1
U39463 356 aa 1
U39464 356 aa 1
U39465 356 aa 1
U39466 356 aa 1
B7A2*02 AK172548 Tr:Q3T9F8 309 aa 2
B7A2*03 AK170054 Tr:Q3TDR5 309 aa 2
B7A2*04 BC013807 Tr:Q91YV7 309 aa 2
NM_019388 NP_062261 309 aa 2
IMGT notes:
  1. (1) Three alternative spliced transcripts are mentioned in PUBMED:7499829. Splicing A (356 aa) has exons EX1,2 and EX6-11. Splicing C (314 aa) has exons EX5 and EX7-11. Splicing B (309 aa) has exons EX4 and EX7-11. No cDNA is available for splicing C.
  2. (2) Splicing B. In EX8 [D2] a79>g; K26>R, positions according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
  3. (3) Splicing B. In EX8 [D2] a288.4>g; K96.4>R, positions according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
  4. (4) Splicing B. Five nucleotide variations in EX7 [D1], EX8 [D2] and EX9.
IMGT references:
  1. [1] Borriello,F. et al. J. Immunol. 155, 5490-5497 (1995). PMID: 7499829

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

B7A2*01: U39456(g) U39457(g) U39461(g) U39462(g) U39463(g) U39464(g) U39465(g) U39466(g)

Nucleotide sequence

1        atggccaaaa ctatccggag actctcggtg gcctttttga cactctcaga caggggaccc

61       cattataaga tcctcctacc tctacctcac aagggctgga ctccaggcct gacccacaat

121      gcctctctct actgtgcctc gatcatttta aaaaacacca tgggcttggc aatccttatc

181      tttgtgacag tcttgctgat ctcagatgct gtttccgtgg agacgcaagc ttatttcaat

241      gggactgcat atctgccgtg cccatttaca aaggctcaaa acataagcct gagtgagctg

301      gtagtatttt ggcaggacca gcaaaagttg gttctgtacg agcactattt gggcacagag

361      aaacttgata gtgtgaatgc caagtacctg ggccgcacga gctttgacag gaacaactgg

421      actctacgac ttcacaatgt tcagatcaag gacatgggct cgtatgattg ttttatacaa

481      aaaaagccac ccacaggatc aattatcctc caacagacat taacagaact gtcagtgatc

541      gccaacttca gtgaacctga aataaaactg gctcagaatg taacaggaaa ttctggcata

601      aatttgacct gcacgtctaa gcaaggtcac ccgaaaccta agaagatgta ttttctgata

661      actaattcaa ctaatgagta tggtgataac atgcagatat cacaagataa tgtcacagaa

721      ctgttcagta tctccaacag cctctctctt tcattcccgg atggtgtgtg gcatatgacc

781      gttgtgtgtg ttctggaaac ggagtcaatg aagatttcct ccaaacctct caatttcact

841      caagagtttc catctcctca aacgtattgg aaggagatta cagcttcagt tactgtggcc

901      ctcctccttg tgatgctgct catcattgta tgtcacaaga agccgaatca gcctagcagg

961      cccagcaaca cagcctctaa gttagagcgg gatagtaacg ctgacagaga gactatcaac

1021     ctgaaggaac ttgaacccca aattgcttca gcaaaaccaa atgcagagtg a
Nucleotide sequence in FASTA format (without gaps) B7A2*01

Amino acid sequence

1        MAKTIRRLSV AFLTLSDRGP HYKILLPLPH KGWTPGLTHN ASLYCASIIL KNTMGLAILI

61       FVTVLLISDA VSVETQAYFN GTAYLPCPFT KAQNISLSEL VVFWQDQQKL VLYEHYLGTE

121      KLDSVNAKYL GRTSFDRNNW TLRLHNVQIK DMGSYDCFIQ KKPPTGSIIL QQTLTELSVI

181      ANFSEPEIKL AQNVTGNSGI NLTCTSKQGH PKPKKMYFLI TNSTNEYGDN MQISQDNVTE

241      LFSISNSLSL SFPDGVWHMT VVCVLETESM KISSKPLNFT QEFPSPQTYW KEITASVTVA

301      LLLVMLLIIV CHKKPNQPSR PSNTASKLER DSNADRETIN LKELEPQIAS AKPNAE*
Amino acid sequence in FASTA format (without gap) B7A2*01

Legend: