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IMGT RPI entry from gene to protein for Mus musculus BTLA

Citing IMGT RPI entry for BTLA

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

BTLA Gene exon/intron organization

Legend:

Number of alleles: 4

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Clones Exons Accession numbers Molecule type
BTLA*01 F EX1-6 AY293285 cDNA
BTLA*02 F MGC:124218 EX1-6 BC108964 cDNA(1)
BTLA*03 F MGC:124217 EX1-6 BC108963 cDNA(2)
BTLA*04 F A630002H24 EX1-6 AK041334 cDNA(3)

IMGT reference sequences (in FASTA format) for the allele(s): BTLA*01 to BTLA*04

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Clones Exons Accession numbers Molecule type
BTLA*01 F EX1-6 NM_001037719 cDNA
BTLA*02 F MGC:155495 EX1-6 NM_177584 cDNA

Corresponding protein database accession numbers

BTLA Accession numbers Number of amino acids Protein isoform
Nucleotide Databases Protein Databases
BTLA*01 AY293285 Q7TSA3 306 aa 1
BTLA*02 BC108964 306 aa 1
BTLA*03 BC108963 305 aa 2
BTLA*04 AK041334 305 aa 2
IMGT notes:
  1. (1) Splicing B lacks the first codon EX4 while preserving the reading frame.
  2. (2) In EX2, a118>c; N40>H numbering according to IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
  3. (3) In EX4, g54>a51; E19>18.
  4. (4) mutations are many.

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

BTLA*01: AY293285(c)

Nucleotide sequence

1        atgaagacag tgcctgccat gcttgggact cctcggttat ttagggaatt cttcatcctc

61       catctgggcc tctggagcat cctttgtgag aaagctacta agaggaatga tgaagagtgt

121      gaagtgcaac ttaatattaa gaggaattcc aaacactctg cctggacagg agagttattt

181      aaaattgaat gtcctgtgaa atactgtgtt catagaccta atgtgacttg gtgtaagcac

241      aatggaacaa tctgggtacc ccttgaagtt ggtcctcagc tatacactag ttgggaagaa

301      aatcgatcag ttccggtttt tgttctccat tttaaaccaa tacatctcag tgataacggg

361      tcgtatagct gttctacaaa cttcaattct caagttatta atagccattc agtaaccatc

421      catgtgagag aaaggactca aaactcttca gaacacccac taataacagt atctgacatc

481      ccagatgcca ccaatgcctc aggaccatcc accatggaag agaggccagg caggacttgg

541      ctgctttaca ccttgcttcc tttgggggca ttgcttctgc tccttgcctg tgtctgcctg

601      ctctgctttc tgaaaaggat ccaagggaaa gaaaagaagc cttctgactt ggcaggaagg

661      gacactaacc tggttgatat tccagccagt tccaggacaa atcaccaagc actgccatca

721      ggaactggaa tttatgataa tgatccctgg tctagcatgc aggatgaatc tgaattgaca

781      attagcttgc aatcagagag aaacaaccag ggcattgttt atgcttcttt gaaccattgt

841      gttattggaa ggaatccaag acaggaaaac aacatgcagg aggcacccac agaatatgca

901      tccatttgtg tgagaagtta a
Nucleotide sequence in FASTA format (without gaps) BTLA*01

Amino acid sequence

1        MKTVPAMLGT PRLFREFFIL HLGLWSILCE KATKRNDEEC EVQLNIKRNS KHSAWTGELF

61       KIECPVKYCV HRPNVTWCKH NGTIWVPLEV GPQLYTSWEE NRSVPVFVLH FKPIHLSDNG

121      SYSCSTNFNS QVINSHSVTI HVRERTQNSS EHPLITVSDI PDATNASGPS TMEERPGRTW

181      LLYTLLPLGA LLLLLACVCL LCFLKRIQGK EKKPSDLAGR DTNLVDIPAS SRTNHQALPS

241      GTGIYDNDPW SSMQDESELT ISLQSERNNQ GIVYASLNHC VIGRNPRQEN NMQEAPTEYA

301      SICVRS*
Amino acid sequence in FASTA format (without gap) BTLA*01

Legend: